Primary Site >> Colorectal Cancer
Gene >> POU5F1
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Ref: A vasoactive intestinal peptide receptor analog alters the expression of homeobox genes. PMID: 12270759 |
Ref: Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene. PMID: 17322106 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. PMID: 17611704 Ref: Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells. PMID: 17671748 |
Ref: Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines. PMID: 18508032 Ref: Significance of organic cation transporter 3 (SLC22A3) expression for the cytotoxic effect of oxaliplatin in colorectal cancer. PMID: 18710896 Ref: The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. PMID: 18949397 |
Ref: Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells. PMID: 19554373 Ref: Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. PMID: 19657699 Ref: [Cultivation and characterization of tumor spheres generated from human colorectal cancer cell lines]. PMID: 19950614 |
Ref: Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. PMID: 20176655 Ref: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. PMID: 20630067 |
Ref: MicroRNA expression profile of colon cancer stem-like cells in HT29 adenocarcinoma cell line. PMID: 21130073 Ref: Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells. PMID: 21435460 Ref: LIN28B promotes colon cancer progression and metastasis. PMID: 21512136 Ref: [Expressions of OCT4 and CD133 and their correlation in colonic cancer]. PMID: 21868340 Ref: Oct4-related cytokine effects regulate tumorigenic properties of colorectal cancer cells. PMID: 22037460 Ref: CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer. PMID: 22848268 |
Ref: OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer. PMID: 21480394 Ref: Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells. PMID: 22205615 Ref: Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells. PMID: 22384170 Ref: Dicer 1, ribonuclease type III modulates a reprogramming effect in colorectal cancer cells. PMID: 22446887 Ref: Genetic variations in stem cell-related genes and colorectal cancer prognosis. PMID: 22528324 Ref: Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy. PMID: 22711167 Ref: Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells. PMID: 22902753 Ref: Epithelial cell adhesion molecule regulates tumor initiation and tumorigenesis via activating reprogramming factors and epithelial-mesenchymal transition gene expression in colon cancer. PMID: 22989882 |
Ref: OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. PMID: 23076549 Ref: NANOG modulates stemness in human colorectal cancer. PMID: 23085761 Ref: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers. PMID: 23175153 Ref: Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells. PMID: 23245395 Ref: A signature for induced pluripotent stem cell-associated genes in colorectal cancer. PMID: 23307247 Ref: Oct-4 is required for an antiapoptotic behavior of chemoresistant colorectal cancer cells enriched for cancer stem cells: effects associated with STAT3/Survivin. PMID: 23340171 Ref: Excellence in cell signaling research recognized with major new award. PMID: 23497077 Ref: Prognostic value of changes in the expression of stem cell markers in the peripheral blood of patients with colon cancer. PMID: 23545848 Ref: MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells. PMID: 23619912 Ref: Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. PMID: 23677573 Ref: Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs. PMID: 23736004 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. PMID: 24023739 Ref: In vitro characterization of stem cell-like properties of drug-resistant colon cancer subline. PMID: 24330852 Ref: AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas. PMID: 24396595 Ref: [In vitro derivation and characterization of a colorectal cancer stem cell subpopulation]. PMID: 24592739 Ref: [A comparative analysis of colorectal carcinoma cell lines that differ in metastatic potential]. PMID: 25509104 |
Ref: HIF-1alpha activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells. PMID: 24718784 Ref: IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. PMID: 24816405 Ref: ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer. PMID: 24838609 Ref: Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PMID: 24921652 Ref: Expression of hippo pathway in colorectal cancer. PMID: 24976283 Ref: beta1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells. PMID: 25003232 Ref: Induction of cancer stem cell properties in colon cancer cells by defined factors. PMID: 25006808 Ref: Potential role for the Metnase transposase fusion gene in colon cancer through the regulation of key genes. PMID: 25333365 Ref: Preoperative low dose NSAID treatment influences the genes for stemness, growth, invasion and metastasis in colorectal cancer. PMID: 25340937 Ref: Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling. PMID: 25396735 Ref: High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients. PMID: 25500546 |
Ref: Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a. PMID: 24837369 Ref: A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer: Research for Reprogramming of Cancer Cells by MicroRNAs. PMID: 25384704 Ref: Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells. PMID: 25404486 Ref: Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer. PMID: 25497006 Ref: The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells. PMID: 25625841 Ref: Lithium chloride induces mesenchymaltoepithelial reverting transition in primary colon cancer cell cultures. PMID: 25738332 Ref: Pluripotency transcription factors in the pathogenesis of colorectal cancer and implications for prognosis. PMID: 25808439 Ref: The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers. PMID: 25906747 Ref: MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells. PMID: 25970424 Ref: Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer. PMID: 26020117 Ref: Correlation of HIWI and HILI Expression with Cancer Stem Cell Markers in Colorectal Cancer. PMID: 26026091 Ref: Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer. PMID: 26106421 Ref: Simultaneous inhibition of EGFR/VEGFR and cyclooxygenase-2 targets stemness-related pathways in colorectal cancer cells. PMID: 26107817 Ref: Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells. PMID: 26185996 Ref: Inhibition of CD147 expression by RNA interference reduces proliferation, invasion and increases chemosensitivity in cancer stem cell-like HT-29 cells. PMID: 26316167 Ref: [SUPPRESSION OF TUMOR GROWTH AFTER XENOGRAFTING OF HUMAN COLORECTAL CARCINOMA CELLS]. PMID: 26349245 Ref: OCT4B1 promotes cell growth, migration and invasion suppressing sensitivity to omicronxaliplatin in colon cancer. PMID: 26398480 Ref: Verification of ALDH Activity as a Biomarker in Colon Cancer Stem Cells-Derived HT-29 Cell Line. PMID: 26634106 Ref: Comparison of gene expression of SOX2 and OCT4 in normal tissue, polyps, and colon adenocarcinoma using immunohistochemical staining. PMID: 26645019 |
Ref: Isolation of colorectal cancer stem-like cells. PMID: 25535115 Ref: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases. PMID: 26031752 Ref: What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue. PMID: 26745821 Ref: Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells. PMID: 26752044 Ref: MACC1 Induces Tumor Progression in Transgenic Mice and Colorectal Cancer Patients via Increased Pluripotency Markers Nanog and Oct4. PMID: 26758557 Ref: Assessment of the Relation between the Expression of Oxaliplatin Transporters in Colorectal Cancer and Response to FOLFOX-4 Adjuvant Chemotherapy: A Case Control Study. PMID: 26859833 Ref: GeneGazer: A Toolkit Integrating Two Pipelines for Personalized Profiling and Biosignature Identification. PMID: 26912804 Ref: Increased chemoresistance via Snail-Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative. PMID: 26992205 Ref: CCL21 Facilitates Chemoresistance and Cancer Stem Cell-Like Properties of Colorectal Cancer Cells through AKT/GSK-3beta/Snail Signals. PMID: 27057280 Ref: The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer. PMID: 27145365 Ref: Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. PMID: 27225481 Ref: The Effect of Analogues of 1alpha,25-Dihydroxyvitamin D(2) on the Regrowth and Gene Expression of Human Colon Cancer Cells Refractory to 5-Fluorouracil. PMID: 27314328 Ref: Primary cultures of human colon cancer as a model to study cancer stem cells. PMID: 27449036 Ref: Apoptotic pathways and stemness in the colorectal epithelium and lamina propria mucosae during the human embryogenesis and carcinogenesis. PMID: 27612611 Ref: A comparison of cancer stem cell markers and nonclassical major histocompatibility complex antigens in colorectal tumor and noncancerous tissues. PMID: 27806848 |
Ref: Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells. PMID: 27832659 Ref: Expression of the cancer stem cell markers ABCG2 and OCT-4 in right-sided colon cancer predicts recurrence and poor outcomes. PMID: 28212529 Ref: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer. PMID: 28237538 Ref: IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment. PMID: 28249897 Ref: Chitosan promotes cancer progression and stem cell properties in association with Wnt signaling in colon and hepatocellular carcinoma cells. PMID: 28367998 Ref: Targeting colon cancer stem cells with novel blood cholesterol drug pitavastatin. PMID: 28387909 Ref: Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion. PMID: 28453235 Ref: Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model. PMID: 28545668 Ref: Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue. PMID: 28596815 Ref: Cholesterol Enhances Colorectal Cancer Progression via ROS Elevation and MAPK Signaling Pathway Activation. PMID: 28618417 Ref: Proinflammatory Cytokines IL-6 and TNF-alpha Increased Telomerase Activity through NF-kappaB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells. PMID: 28676732 Ref: The Tissue-Reconstructing Ability of Colon CSCs Is Enhanced by FK506 and Suppressed by GSK3 Inhibition. PMID: 28710230 Ref: Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. PMID: 28833104 Ref: Clinical significance of Fusobacterium nucleatum, epithelial-mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients. PMID: 29081665 Ref: Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer. PMID: 29179207 Ref: An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer. PMID: 29196508 Ref: Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis. PMID: 29254234 Ref: Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver. PMID: 29404335 |
Ref: Correlation of Cancer Stem-Cell Markers OCT4, SOX2, and NANOG with Clinicopathological Features and Prognosis in Operative Patients with Rectal Cancer. PMID: 29214774 Ref: Relevance of copper transporter 1 and organic cation transporters 1-3 for oxaliplatin uptake and drug resistance in colorectal cancer cells. PMID: 29417972 Ref: Ectopic expression of miR-147 inhibits stem cell marker and epithelial-mesenchymal transition (EMT)-related protein expression in colon cancer cells. PMID: 29426374 Ref: New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells. PMID: 29439916 Ref: High RAC3 expression levels are required for induction and maintaining of cancer cell stemness. PMID: 29464039 Ref: The POU5F1 gene expression in colorectal cancer: a novel prognostic marker. PMID: 29488015 Ref: Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells. PMID: 29568348 Ref: Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways. PMID: 29568377 Ref: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer. PMID: 29627827 Ref: High Oct4 predicted worse prognosis of right-sided colon cancer patients. PMID: 29656661 Ref: [LincRNA-ROR functions as a ceRNA to regulate Oct4, Sox2, and Nanog expression by sponging miR-145 and its effect on biologic characteristics of colonic cancer stem cells]. PMID: 29690669 Ref: Protein arginine methyltransferase 8 gene enhances the colon cancer stem cell (CSC) function by upregulating the pluripotency transcription factor. PMID: 29721049 Ref: Renal Cell Carcinoma, Unclassified with Medullary Phenotype and Synchronous Renal Clear Cell Carcinoma Present in a Patient with No Sickle Cell Trait/Disease: Diagnostic and Therapeutic Challenges. PMID: 29848739 Ref: R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells. PMID: 29886802 Ref: The pluripotency network in colorectal cancer pathogenesis and prognosis: an update. PMID: 29944017 Ref: miR-106a Reduces 5-Fluorouracil (5-FU) Sensitivity of Colorectal Cancer by Targeting Dual-Specificity Phosphatases 2 (DUSP2). PMID: 30011263 Ref: Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis. PMID: 30091203 Ref: OCT4 Potentiates Radio-Resistance and Migration Activity of Rectal Cancer Cells by Improving Epithelial-Mesenchymal Transition in a ZEB1 Dependent Manner. PMID: 30112378 Ref: Three-Dimensional Ameliorated Biologics Elicit Thymic Renewal in Tumor-Bearing Hosts. PMID: 30150284 Ref: Hypomethylation of NANOG promoter in colonic mucosal cells of obese patients: a possible role of NF-kappaB. PMID: 30157990 Ref: Effect of Cinnamic acid and FOLFOX in diminishing side population and downregulating cancer stem cell markers in colon cancer cell line HT-29. PMID: 30209760 Ref: Solasodine reverses stemness and epithelial-mesenchymal transition in human colorectal cancer. PMID: 30268504 Ref: Using of keratin substrate for enrichment of HT29 colorectal cancer stem-like cells. PMID: 30281900 Ref: Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture. PMID: 30284085 |