Primary Site >> Colorectal Cancer
Gene >> PMAIP1
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Ref: Intermittent percutaneous infusion into the hepatic artery of cytotoxic drugs for hepatic tumours. PMID: 7055763 |
Ref: [Amputation of the rectum by the perineosacral approach for anorectal cancer. Indications, results. Apropos of 27 cases]. PMID: 4086522 |
Ref: [Functional preservation in rectal cancer surgery]. PMID: 3067070 |
Ref: [Local excision of rectal tumors: Y. Mason's operation]. PMID: 7788808 Ref: Local excision and postoperative radiation therapy for rectal cancer. PMID: 8092113 |
Ref: Preservation of the anus in the therapy of distal rectal cancers. PMID: 9092118 |
Ref: Preoperative chemoradiation for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, and sphincter preservation. PMID: 9539561 |
Ref: Conservative management of rectal cancer with local excision and postoperative adjuvant therapy. PMID: 10386641 Ref: [Role of curative local excision in rectal cancer]. PMID: 10692792 |
Ref: Rectal cancer: the sphincter-sparing approach. PMID: 12507204 |
Ref: Nationwide decline in annual numbers of abdomino-perineal resections: effect of a successful national trial? PMID: 12780910 Ref: Noxa in colorectal cancer: a study on DNA, mRNA and protein expression. PMID: 12879012 Ref: [Postoperative complications and local recurrence of mid-lower rectal carcinoma treated with neoadjuvant chemoradiotherapy and surgery. Preliminary results]. PMID: 12903576 Ref: Transvaginal local excision of rectal carcinoma. PMID: 14972221 Ref: Evaluation of DOWNSTAGING as leading concept in sphincter-saving surgery for rectal cancer after preoperative radio-chemotherapy (Preop RCT). PMID: 15139712 |
Ref: Plastic and reconstructive surgery approaches in the management of anal cancer. PMID: 15137961 Ref: Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. PMID: 15604280 |
Ref: Treatment of rectal cancer by chemoradiation followed by surgery: analysis and early clinical outcome in 66 patients. PMID: 15984381 Ref: [Indications and prognostic analysis of sphincter preservation operation for rectal cancer]. PMID: 16167243 Ref: Vaginal reconstruction with vertically oriented rectus abdominus myocutaneous (VRAM) flap following APR for locally advanced rectal cancer. PMID: 16341478 |
Ref: [Multivariate prognostic analysis of patients with low and middle rectal cancer after curative resection]. PMID: 16687079 |
Ref: Lymph node clearance after total mesorectal excision for rectal cancer: laparoscopic versus open approach. PMID: 17384514 Ref: The influence of type of operation for distal rectal cancer: survival, outcomes, and recurrence. PMID: 17523284 Ref: Comparative outcome between chemoradiotherapy and lateral pelvic lymph node dissection following total mesorectal excision in rectal cancer. PMID: 17968166 Ref: [The role of neoadjuvant radio-chemotherapy in the treatment of rectal cancer]. PMID: 18510028 Ref: Laparoscopic assisted distal rectal cancer resection with preoperative concurrent chemoradiotherapy. PMID: 19746227 |
Ref: Isolated chemotherapeutic perfusion of pelvis as neoadjuvant or palliative therapy for advanced cancer of the rectum. PMID: 18157578 Ref: The simple "Rectum Catcher" device is a useful tool for laparoscopic-assisted high and lower rectal surgery. PMID: 18461386 Ref: Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis. PMID: 18577376 Ref: Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. PMID: 18607570 Ref: Prognostic impact of bim, puma, and noxa expression in human colon carcinomas. PMID: 18794091 Ref: Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. PMID: 19088028 Ref: Modifiable risk factors in colorectal surgery: central role of surgeon's volume. PMID: 19354037 |
Ref: Neoadjuvant chemoradiation for rectal cancer reduces lymph node harvest in proctectomy specimens. PMID: 18850250 Ref: [Preoperative chemoradiotherapy for resectable lower rectal cancer]. PMID: 20037306 |
Ref: Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. PMID: 20354524 Ref: ACR Appropriateness Criteria: local excision in early-stage rectal cancer. PMID: 20541057 Ref: Preoperative chemoradiotherapy for rectal cancer: a comparison between intravenous 5-fluorouracil and oral capecitabine. PMID: 20618366 |
Ref: Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1. PMID: 20812030 Ref: Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737. PMID: 21468686 |
Ref: Prostatic marker needles to define the anterior dissection planes during APR for rectal cancers in patients with previous radiotherapy for prostate cancer. PMID: 21909846 Ref: Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak. PMID: 22056880 Ref: P53 mediates estradiol induced activation of apoptosis and DNA repair in non-malignant colonocytes. PMID: 22100717 Ref: Abdominoperineal excision: evolution of a centenary operation. PMID: 22810469 Ref: [Research progress of cylindrical abdominoperineal resection/extralevator abdominoperineal excision for advanced low rectal cancer]. PMID: 23099898 Ref: Advanced anal squamous cell carcinoma -- radiotherapy or surgery? PMID: 23116837 |
Ref: Use of the gluteus maximus muscle as the neosphincter for restoration of anal function after abdominoperineal resection. PMID: 23242561 Ref: Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA. PMID: 23499448 Ref: MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death. PMID: 23816886 Ref: Evolving role of neoadjuvant therapy in rectal cancer. PMID: 23828092 Ref: Sphincter-preserving surgery for rectal cancer: a population-based study in Taiwan. PMID: 24046831 Ref: Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue. PMID: 24055891 Ref: [Three major problems and solutions in laparoscopic abdominoperineal resection for rectal carcinoma]. PMID: 24158866 |
Ref: Transanal endoscopic microsurgery after endoscopic resection of malignant rectal polyps: a useful technique for indication to radical treatment. PMID: 24170069 Ref: Anti-tumoral effect of the mitochondrial target domain of Noxa delivered by an engineered Salmonella typhimurium. PMID: 24416126 Ref: Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex. PMID: 24452144 Ref: LincRNA-p21 enhances the sensitivity of radiotherapy for human colorectal cancer by targeting the Wnt/beta-catenin signaling pathway. PMID: 24573322 Ref: Long-term prognostic value of mesorectal grading after neoadjuvant chemoradiotherapy for rectal cancer. PMID: 24581995 Ref: Association between markers of glucose metabolism and risk of colorectal adenoma. PMID: 24632359 Ref: A comparison of the technical and oncologic validity between robot-assisted and conventional open abdominoperineal resection. PMID: 24913254 Ref: Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. PMID: 25285768 Ref: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination. PMID: 25386076 Ref: [Two cases of intrapelvic recurrence after radical resection of rectal cancer, treated with carbon ion radiotherapy]. PMID: 25731303 |
Ref: Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells. PMID: 25548100 Ref: Magnetic resonance imaging based rectal cancer classification: landmarks and technical standardization. PMID: 25593457 Ref: [Appropriate dosing of fosaprepitant for colon cancer patients]. PMID: 25743141 Ref: Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway. PMID: 26028667 Ref: Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer. PMID: 26134786 Ref: Surgical Options in the Treatment of Lower Gastrointestinal Tract Cancers. PMID: 26188639 Ref: PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms. PMID: 26452133 Ref: Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. PMID: 26485768 Ref: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. PMID: 26590805 Ref: Morbidity and Mortality Following Short Course Preoperative Radiotherapy in Rectal Carcinoma. PMID: 26615375 |
Ref: Outcomes in 132 patients following laparoscopic total mesorectal excision (TME) for rectal cancer with greater than 5-year follow-up. PMID: 25907863 Ref: A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation. PMID: 26375985 Ref: Management of postoperative bladder emptying after proctectomy in men for rectal cancer. A retrospective study of 190 consecutive patients. PMID: 26694925 Ref: Predictors of circumferential resection margin involvement in surgically resected rectal cancer: A retrospective review of 23,464 patients in the US National Cancer Database. PMID: 26906328 Ref: Recognition of Anterior Peritoneal Reflections and Their Relationship With Rectal Tumors Using Rectal Magnetic Resonance Imaging. PMID: 26945377 Ref: Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting. PMID: 27083053 Ref: Temporal Trends in Colorectal Cancer Screening among Asian Americans. PMID: 27197273 Ref: Prospective assessment of the quality of life in patients treated surgically for rectal cancer with lower anterior resection and abdominoperineal resection. PMID: 27514720 Ref: Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells. PMID: 27517746 |
Ref: Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains. PMID: 27222126 Ref: TFF3-dependent resistance of human colorectal adenocarcinoma cells HT-29/B6 to apoptosis is mediated by miR-491-5p regulation of lncRNA PRINS. PMID: 28149533 Ref: Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin. PMID: 28284059 Ref: Ileal strangulation by a secondary perineal hernia after laparoscopic abdominoperineal rectal resection: A case report. PMID: 28292663 Ref: In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. PMID: 28573788 Ref: Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer. PMID: 28627647 Ref: The BET-Bromodomain Inhibitor JQ1 synergized ABT-263 against colorectal cancer cells through suppressing c-Myc-induced miR-1271-5p expression. PMID: 28950657 Ref: [Discovery, anatomy and clinical significance of the mesorectal finish line of total mesorectal excision]. PMID: 29130229 Ref: A Prospective Study of Distal Microscopic Spread in Rectal Cancer After Neoadjuvant Chemoradiation in Pinned and Unpinned Specimen. PMID: 29203975 Ref: Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway. PMID: 29254217 |
Ref: CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA. PMID: 28749203 Ref: Resected irradiated rectal cancers: Are twelve lymph nodes really necessary in the era of neoadjuvant therapy? PMID: 28890055 Ref: Outcomes following completion and salvage surgery for early rectal cancer: A systematic review. PMID: 29174708 Ref: Full-thickness neorectal prolapse after transanal transabdominal proctosigmoidectomy for low rectal cancer: a cohort study. PMID: 29363246 Ref: Betulin induces cytochrome c release and apoptosis in colon cancer cells via NOXA. PMID: 29725447 Ref: MRI-based EMVI positivity predicts systemic recurrence in rectal cancer patients with a good tumor response to chemoradiotherapy followed by surgery. PMID: 29790177 Ref: Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins. PMID: 29895675 Ref: Knockdown of Mir-135b Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Apoptosis Through Increase of FOXO1. PMID: 30071508 |