Primary Site >> Colorectal Cancer

Gene >> PLA2G4A

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Ref: Cohorts with familial disposition for colon cancers in chemoprevention trials.
PMID: 9027609
Ref: Gene expression of cyclooxygenase-2, group II and cytosolic phospholipase A2 in human colorectal cancer.
PMID: 9858896
Ref: The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells.
PMID: 10334889
Ref: Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs.
PMID: 10706128
Ref: Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis.
PMID: 11274413
Ref: Expression of cytosolic and group X secretory phospholipase A(2) genes in human colorectal adenocarcinomas.
PMID: 12048163
Ref: Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis.
PMID: 12584182
Ref: Inhibition of cytosolic phospholipase A2 mRNA expression: a novel mechanism for acetylsalicylic acid-mediated growth inhibition and apoptosis in colon cancer cells.
PMID: 12832097
Ref: Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.
PMID: 15073046
Ref: Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis.
PMID: 15788676
Ref: Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis.
PMID: 15805260
Ref: Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells.
PMID: 15975962
Ref: Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production.
PMID: 16458424
Ref: Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells.
PMID: 16467083
Ref: Defective arachidonate release and PGE2 production in Gi alpha2-deficient intestinal and colonic subepithelial myofibroblasts.
PMID: 16534415
Ref: Impacts of cytosolic phospholipase A2, 15-prostaglandin dehydrogenase, and cyclooxygenase-2 expressions on tumor progression in colorectal cancer.
PMID: 20635443
Ref: Prognostic significance of cytosolic phospholipase A2 expression in patients with colorectal cancer.
PMID: 22066066
Ref: PLA2G4A mutants modified protective effect of tea consumption against colorectal cancer.
PMID: 22358383
Ref: Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells.
PMID: 29374817
Ref: Interferon-gamma induces autophagy-associated apoptosis through induction of cPLA2-dependent mitochondrial ROS generation in colorectal cancer cells.
PMID: 29551681