Primary Site >> Stomach Cancer

Gene >> PINX1

  • 2005
  • 2009
  • 2010
  • 2011
  • 2017
Ref: Loss of heterozygosity and histone hypoacetylation of the PINX1 gene are associated with reduced expression in gastric carcinoma.
PMID: 15637589
Ref: The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population.
PMID: 18784941
Ref: PinX1 inhibits telomerase activity in gastric cancer cells through Mad1/c-Myc pathway.
PMID: 20544396
Ref: PinX1 gene transfection enhances the sensitivity of gastric carcinoma cell line to 5-fluorouracil.
PMID: 21661452
Ref: Silencing of the hPOT1 gene by RNA inference promotes apoptosis and inhibits proliferation and aggressive phenotype of gastric cancer cells, likely through up-regulating PinX1 expression.
PMID: 21778296
Ref: REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype.
PMID: 27212034