Primary Site >> Colorectal Cancer

Gene >> PINX1

  • 2014
  • 2015
  • 2016
  • 2017
  • 2018
Ref: PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells.
PMID: 24839934
Ref: Decreased expression of PinX1 protein predicts poor prognosis of colorectal cancer patients receiving 5-FU adjuvant chemotherapy.
PMID: 26211574
Ref: PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis.
PMID: 27536146
Ref: NF-kappaB potentiates tumor growth by suppressing a novel target LPTS.
PMID: 29017500
Ref: Pin2/TRF1binding protein X1 inhibits colorectal cancer cell migration and invasion in vitro and metastasis in vivo via the nuclear factorkappaB signaling pathway.
PMID: 30015978
Ref: Impact of the Localization of the Primary Tumor and RAS/BRAF Mutational Status on Maintenance Strategies After First-line Oxaliplatin, Fluoropyrimidine, and Bevacizumab in Metastatic Colorectal Cancer: Results From the AIO 0207 Trial.
PMID: 30145148