Primary Site >> Liver Cancer

Gene >> PIK3R1

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Ref: The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
PMID: 20530665
Ref: Various effects of hepatoma-derived growth factor on cell growth, migration and invasion of breast cancer and prostate cancer cells.
PMID: 21567096
Ref: miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma.
PMID: 22684007
Ref: Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma.
PMID: 25120700
Ref: [Roles of PIK3R1 gene in development of hepatocellular carcinoma].
PMID: 25372641
Ref: MicroRNA-486-5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1.
PMID: 25475121
Ref: miR-128-3p suppresses hepatocellular carcinoma proliferation by regulating PIK3R1 and is correlated with the prognosis of HCC patients.
PMID: 25962360
Ref: Interaction of key pathways in sorafenib-treated hepatocellular carcinoma based on a PCR-array.
PMID: 26045814
Ref: Screening for the protective effect target of deproteinized extract of calf blood and its mechanisms in mice with CCl4-induced acute liver injury.
PMID: 28700704