Primary Site >> Pancreatic Cancer

Gene >> PIK3CG

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Ref: Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells.
PMID: 19032736
Ref: Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM).
PMID: 20581473
Ref: Novel agents for the treatment of pancreatic adenocarcinoma. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011.
PMID: 21737890
Ref: Phase I study of Rigosertib, an inhibitor of the phosphatidylinositol 3-kinase and Polo-like kinase 1 pathways, combined with gemcitabine in patients with solid tumors and pancreatic cancer.
PMID: 22338014
Ref: Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.
PMID: 24521981
Ref: Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells.
PMID: 25016056
Ref: Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts.
PMID: 25360116
Ref: Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer.
PMID: 25376606
Ref: Therapeutic Benefit of Selective Inhibition of p110alpha PI3-Kinase in Pancreatic Neuroendocrine Tumors.
PMID: 27225693
Ref: Molecular targeted therapy for pancreatic adenocarcinoma: A review of completed and ongoing late phase clinical trials.
PMID: 27613577
Ref: Clinical significance of Akt2 in advanced pancreatic cancer treated with erlotinib.
PMID: 28440469
Ref: Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis.
PMID: 29434912