Primary Site >> Colorectal Cancer

Gene >> PIGR

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Ref: Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor.
PMID: 8227356
 Ref: Dimeric recombinant IgA directed against carcino-embryonic antigen, a novel tool for carcinoma localization.
PMID: 7997243
Ref: Inhibition of IFN-gamma activity in supernatants from stimulated human intestinal mononuclear cells prevents up-regulation of the polymeric Ig receptor in an intestinal epithelial cell line.
PMID: 8021503
 Ref: Secretory component mRNA and protein expression in colorectal adenomas and carcinomas.
PMID: 8664120
 Ref: Transcriptional regulation of the human polymeric immunoglobulin receptor gene by interferon-gamma.
PMID: 9182878
 Ref: Cutting edge: coordinate regulation of IFN regulatory factor-1 and the polymeric Ig receptor by proinflammatory cytokines.
PMID: 9973374
 Ref: Human intestinal epithelial cells express a novel receptor for IgA.
PMID: 10799857
 Ref: Characterization of the human polymeric immunoglobulin receptor (PIGR) 3'UTR and differential expression of PIGR mRNA during colon tumorigenesis.
PMID: 14631119
 Ref: Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene.
PMID: 14644095
 Ref: Long-term exposure of the HT-29 human intestinal epithelial cell line to TNF causes sustained up-regulation of the polymeric Ig receptor and proinflammatory genes through transcriptional and posttranscriptional mechanisms.
PMID: 15905574
 Ref: Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.
PMID: 21262260
 Ref: ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis.
PMID: 22213796
 Ref: COLORECTAL Polymeric Immunoglobulin Receptor Expression is Correlated with Hepatic Metastasis and Poor Prognosis in Colon Carcinoma Patients with Hepatic Metastasis.
PMID: 26176052