Primary Site >> Colorectal Cancer

Gene >> PIDD1

  • 2006
  • 2010
  • 2016
Ref: Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage.
PMID: 16652156
Ref: Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer.
PMID: 17090686
Ref: Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.
PMID: 21078189
Ref: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
PMID: 27622714