Primary Site >> Liver Cancer
Gene >> PI3
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Ref: Proteomic analysis of cholangiocarcinoma cell line. PMID: 15048994 |
Ref: Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. PMID: 16036916 Ref: Proteomic analysis of differentially expressed proteins in hepatocellular carcinoma developed in patients with chronic viral hepatitis C. PMID: 16097030 Ref: Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells. PMID: 16139919 |
Ref: Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma. PMID: 16327976 Ref: Proteome analysis of hepatocellular carcinoma by laser capture microdissection. PMID: 16342242 Ref: Expressed proteome analysis of human hepatocellular carcinoma in nude mice (LCI-D20) with high metastasis potential. PMID: 16372266 Ref: Novel cisplatin-type platinum complexes and their cytotoxic activity. PMID: 16554155 Ref: Cytotoxicity of bioactive polymeric fractions from grape cell culture on human hepatocellular carcinoma, murine leukemia and non-cancerous PK15 kidney cells. PMID: 16828532 Ref: Identification of metastasis candidate proteins among HCC cell lines by comparative proteome and biological function analysis of S100A4 in metastasis in vitro. PMID: 17051636 |
Ref: Comparative proteomics of rat liver and Morris hepatoma 7777 plasma membranes. PMID: 16987716 Ref: Identification of human hepatocellular carcinoma-related proteins by proteomic approaches. PMID: 17447055 Ref: Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. PMID: 17626077 Ref: [Identification of a naturally presented MAGE-A3 epitope on the surface of HLE cell line by mass spectrometry]. PMID: 17688791 |
Ref: Transgenic overexpression of insulin receptor substrate 1 in hepatocytes enhances hepatocellular proliferation in young mice only. PMID: 18631251 |
Ref: Identification of N-glycosylation sites on secreted proteins of human hepatocellular carcinoma cells with a complementary proteomics approach. PMID: 19196183 Ref: Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae). PMID: 19379837 Ref: Lignan constituents from Chloranthus japonicus Sieb. PMID: 19387574 Ref: Expression of phospho-ERK1/2 and PI3-K in benign and malignant gallbladder lesions and its clinical and pathological correlations. PMID: 19445727 Ref: Two new biphenanthrenes with cytotoxic activity from Bulbophyllum odoratissimum. PMID: 19446615 Ref: Identification of replication-competent HSV-1 Cgal+ strain targets in a mouse model of human hepatocarcinoma xenograft. PMID: 19540947 Ref: Nanozeolite-driven approach for enrichment of secretory proteins in human hepatocellular carcinoma cells. PMID: 19743415 Ref: Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin. PMID: 19830248 |
Ref: Coronin-1C is a novel biomarker for hepatocellular carcinoma invasive progression identified by proteomics analysis and clinical validation. PMID: 20181269 Ref: Evaluation of plasma carcinogenic markers in rat hepatic tumors models induced by rat hepatoma N1-S1 cells and benzo[a]pyrene. PMID: 20195826 Ref: Characterisation and biological activities of proanthocyanidins from the barks of Pinus massonian and Acacia mearnsii. PMID: 20397109 Ref: Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells. PMID: 20657414 Ref: [Increased coronin-1C expression is related to hepatocellular carcinoma invasion and metastasis]. PMID: 20678442 |
Ref: Bevacizumab enhances chemosensitivity of hepatocellular carcinoma to adriamycin related to inhibition of survivin expression. PMID: 20490863 Ref: Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. PMID: 21220499 Ref: Triterpenes and steroids from the roots of Scorzonera austriaca. PMID: 21238545 Ref: Aspirin reduces the apoptotic effect of etoposide via Akt activation and up-regulation of p21(cip). PMID: 21617849 Ref: Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways. PMID: 21786165 Ref: Identification of transaldolase as a novel serum biomarker for hepatocellular carcinoma metastasis using xenografted mouse model and clinic samples. PMID: 22023829 |
Ref: In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma. PMID: 22245841 Ref: Two new saponins from Thalictrum fortunei. PMID: 22375870 Ref: Spectroscopic identification of new ellagitannins and a trigalloyl-glucosylkaempferol from an extract of Euphorbia cotinifolia L. with antitumour and antioxidant activity. PMID: 22624331 Ref: Heterocycle-functional gramine analogues: solvent- and catalyst-free synthesis and their inhibition activities against cell proliferation. PMID: 22647218 Ref: Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: design, synthesis and biological evaluation. PMID: 22727445 Ref: Tumor-derived secretory clusterin induces epithelial-mesenchymal transition and facilitates hepatocellular carcinoma metastasis. PMID: 23010347 Ref: Anticancer constituents and cytotoxic activity of methanol-water extract of Polygonum bistorta L. PMID: 24082326 |
Ref: Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma. PMID: 23232767 Ref: Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma. PMID: 23489999 Ref: Identification of histone deacetylase 1 protein complexes in liver cancer cells. PMID: 23621261 Ref: Two new vinblastine-type N-oxide alkaloids from Catharanthus roseus. PMID: 23621523 Ref: Protein expression profiling of nuclear membrane protein reveals potential biomarker of human hepatocellular carcinoma. PMID: 23724895 Ref: PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation. PMID: 23769634 Ref: PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma. PMID: 24176221 Ref: Insulin resistance: mechanism and implications for carcinogenesis and hepatocellular carcinoma in NASH. PMID: 26202296 |
Ref: Chemical profiles and anticancer effects of saponin fractions of different polarity from the leaves of Panax notoginseng. PMID: 24484594 Ref: Over-expressed Testis-specific Protein Y-encoded 1 as a novel biomarker for male hepatocellular carcinoma. PMID: 24586606 Ref: Thiosemicarbazone Cu(II) and Zn(II) complexes as potential anticancer agents: syntheses, crystal structure, DNA cleavage, cytotoxicity and apoptosis induction activity. PMID: 24690556 |
Ref: Two new triterpenoid saponins obtained by microbial hydrolysis with Alternaria alternata AS 3.6872. PMID: 25421632 Ref: Synthesis and characterization of Schiff base octaazamacrocyclic complexes and their biological studies. PMID: 25490374 Ref: Biotransformation on the triterpenoid saponin of Ardisia gigantifolia by Aspergillus avenaceus AS 3.4454. PMID: 25494647 Ref: PTPN11/Shp2 overexpression enhances liver cancer progression and predicts poor prognosis of patients. PMID: 25865556 Ref: psi-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling. PMID: 25890498 Ref: Secondary metabolites from the root of Lindera reflexa Hemsl. PMID: 26176582 Ref: Dihydrochalcone Compounds Isolated from Crabapple Leaves Showed Anticancer Effects on Human Cancer Cell Lines. PMID: 26633321 |
Ref: Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy. PMID: 26175166 Ref: Potential Molecular Targeted Therapeutics: Role of PI3-K/Akt/mTOR Inhibition in Cancer. PMID: 26179270 Ref: Two novel prenylated kaempferol derivatives from fresh bud's fur of Platanus acerifolia and their anti-proliferative activities. PMID: 26736086 Ref: Role of Akt inhibition on Notch1 expression in hepatocellular carcinoma: potential role for dual targeted therapy. PMID: 26850133 Ref: Synthesis, characterization of alpha-amino acid Schiff base derived Ru/Pt complexes: Induces cytotoxicity in HepG2 cell via protein binding and ROS generation. PMID: 27002605 Ref: Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entry. PMID: 27012176 Ref: New ent-kaurane diterpenoid dimer from Pulicaria inuloides. PMID: 27348493 Ref: Volatile oil from Saussurea lappa exerts antitumor efficacy by inhibiting epithelial growth factor receptor tyrosine kinase-mediated signaling pathway in hepatocellular carcinoma. PMID: 27806329 |
Ref: Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV. PMID: 27809417 Ref: Cytotoxic clerodane diterpenoids from Croton crassifolius. PMID: 28174107 Ref: Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal. PMID: 28178217 Ref: Hormonemate Derivatives from Dothiora sp., an Endophytic Fungus. PMID: 28277681 Ref: Screening and identification of the tumor-associated antigen CK10, a novel potential liver cancer marker. PMID: 28469975 Ref: The role of miR-130a in cancer. PMID: 28477068 |
Ref: Balanochalcone, a new chalcone from Balanophora laxiflora Hemsl. PMID: 28778140 Ref: LC-ESI-MS/MS and cytotoxic activity of three Pistacia species. PMID: 29376415 Ref: A pair of cyclopeptide epimers from the seeds of Celosia argentea. PMID: 29425591 Ref: HBX protein promotes LASP-1 expression through activation of c-Jun in human hepatoma cells. PMID: 29600594 Ref: C-Phycocyanin inhibits hepatic gluconeogenesis and increases glycogen synthesis via activating Akt and AMPK in insulin resistance hepatocytes. PMID: 29693104 Ref: Effects of COL8A1 on the proliferation of muscle-derived satellite cells. PMID: 29696735 Ref: Two new 18, 19-seco Triterpenoids from Ilex asprella (Hook. et Arn.) Champ. ex Benth. PMID: 29698682 Ref: Long non-coding RNA THOR promotes cell proliferation and metastasis in hepatocellular carcinoma. PMID: 30098425 Ref: Purification, characterization and fine sugar specificity of a N-Acetylgalactosamine specific lectin from Adenia hondala. PMID: 30306293 |