Primary Site >> Pancreatic Cancer
Gene >> PHLPP1
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Ref: The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. PMID: 22044669 Ref: FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer. PMID: 22590527 |
Ref: InterAKTions with FKBPs--mutational and pharmacological exploration. PMID: 23469007 |
Ref: PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells. PMID: 26760962 |
Ref: USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling. PMID: 28363942 |