Primary Site >> Colorectal Cancer
Gene >> PHGDH
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Ref: Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice. PMID: 17283118 Ref: 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. PMID: 17707368 |
Ref: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis. PMID: 22438825 |
Ref: Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer. PMID: 26439504 |
Ref: Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition. PMID: 26716648 Ref: Increased Expression of PHGDH and Prognostic Significance in Colorectal Cancer. PMID: 27267836 Ref: High Expression of PHGDH Predicts Poor Prognosis in Non-Small Cell Lung Cancer. PMID: 27916294 |