Primary Site >> Colorectal Cancer

Gene >> PFKFB3

  • 2005
  • 2013
  • 2014
  • 2016
  • 2017
  • 2018
Ref: Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer.
PMID: 16115917
Ref: TNFalpha and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells.
PMID: 23866118
Ref: Astrocyte elevated gene-1 mediates glycolysis and tumorigenesis in colorectal carcinoma cells via AMPK signaling.
PMID: 24829520
Ref: Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer.
PMID: 26530697
Ref: Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.
PMID: 27171439
Ref: Metabolic reprogramming and AMPKalpha1 pathway activation by caulerpin in colorectal cancer cells.
PMID: 27922662
Ref: Discovery and Structure-Activity Relationships of N-Aryl 6-Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors.
PMID: 30378281