Primary Site >> Colorectal Cancer

Gene >> PF4

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Ref: Hemostasis following inoculation and during spreading of colon carcinoma in the rat.
PMID: 3756913
Ref: Growth inhibition of murine melanoma and human colon carcinoma by recombinant human platelet factor 4.
PMID: 1692094
Ref: Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity.
PMID: 1706960
Ref: Continuing the fight against advanced colorectal cancer: new and future treatment options.
PMID: 9491788
Ref: [Does colorectal cancer clinical advancement and surgical treatment affect platelet factor 4 concentration].
PMID: 15771125
Ref: Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
PMID: 20334899
Ref: Novel multiplex method to assess insulin, leptin and adiponectin regulation of inflammatory cytokines associated with colon cancer.
PMID: 22193626
Ref: VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients.
PMID: 22402885
Ref: CXCL4 mediates tumor regrowth after chemotherapy by suppression of antitumor immunity.
PMID: 26479470
Ref: Angiodrastic Chemokines in Colorectal Cancer: Clinicopathological Correlations.
PMID: 29850390
Ref: Surgical trauma contributes to progression of colon cancer by downregulating CXCL4 and recruiting MDSCs.
PMID: 30055136
Ref: GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF-kappaB signaling pathway in colorectal cancer cells.
PMID: 30267476