Primary Site >> Pancreatic Cancer

Gene >> PENK

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Ref: Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.
PMID: 12000709
Ref: Preproenkephalin hypermethylation in the pure pancreatic juice compared with p53 mutation in the diagnosis of pancreatic carcinoma.
PMID: 16988769
Ref: K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.
PMID: 17198183
Ref: Gene therapy for pancreatitis pain.
PMID: 19262610
Ref: ppENK Gene Methylation Status in the Development of Pancreatic Carcinoma.
PMID: 23781238
Ref: MiR-377 reverses cancerous phenotypes of pancreatic cells via suppressing DNMT1 and demethylating tumor suppressor genes.
PMID: 28758420
Ref: Nicotine induces aberrant hypermethylation of tumor suppressor genes in pancreatic epithelial ductal cells.
PMID: 29626481
Ref: The interaction between miR148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer.
PMID: 30226601