Primary Site >> Liver Cancer
Gene >> PDZD2
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Ref: Interaction of Pin1 with Nek6 and characterization of their expression correlation in Chinese hepatocellular carcinoma patients. PMID: 16476580 |
Ref: Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. PMID: 17383430 Ref: Hepatitis B virus x protein and pin1 in liver cancer: "les liaisons dangereuses". PMID: 17383439 |
Ref: The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. PMID: 19168580 |
Ref: Impairment of the Pin1/E2F1 axis in the anti-proliferative effect of bortezomib in hepatocellular carcinoma cells. PMID: 25742740 Ref: Peptidyl-Prolyl cis/trans Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma. PMID: 26133706 Ref: Prolyl isomerase Pin1 regulates cadmium-induced autophagy via ubiquitin-mediated post-translational stabilization of phospho-Ser GSK3alphabeta in human hepatocellular carcinoma cells. PMID: 26445356 Ref: Pin1 facilitates NF-kappaB activation and promotes tumour progression in human hepatocellular carcinoma. PMID: 26461058 |
Ref: Understanding the role of PIN1 in hepatocellular carcinoma. PMID: 28018099 |
Ref: miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression. PMID: 28076852 Ref: Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways. PMID: 28262728 Ref: MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways. PMID: 28383568 Ref: Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma. PMID: 28404959 Ref: Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. PMID: 29225033 |
Ref: A novel controlled release formulation of the Pin1 inhibitor ATRA to improve liver cancer therapy by simultaneously blocking multiple cancer pathways. PMID: 29170140 Ref: Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development. PMID: 29381806 Ref: Pin1 impairs microRNA biogenesis by mediating conformation change of XPO5 in hepatocellular carcinoma. PMID: 29445125 Ref: Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. PMID: 30093655 |