Primary Site >> Colorectal Cancer

Gene >> PBX2

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Ref: Inhibitory effects of the gastrin receptor antagonist (L-365,260) on gastrointestinal tumor cells.
PMID: 1873778
Ref: Gastrin receptor antagonist CI-988 inhibits growth of human colon cancer in vivo and in vitro.
PMID: 8611133
Ref: [Gastrin-17 and G17-gly induce proliferation of LoVo cells through the CCK B/gastrin receptor].
PMID: 9762332
Ref: Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer.
PMID: 11156225
Ref: Glycine-extended gastrin promotes the invasiveness of human colon cancer cells.
PMID: 11437383
Ref: CCK-B/gastrin receptors in human colorectal cancer.
PMID: 11589724
Ref: Gastrin 17 vaccine--Aphton: Anti-gastrin 17 immunogen, G17DT.
PMID: 12749761
Ref: Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells.
PMID: 14667936
Ref: High and low affinity receptors mediate growth effects of gastrin and gastrin-Gly on DLD-1 human colonic carcinoma cells.
PMID: 14706850
Ref: Importance of N- and C-terminal regions of gastrin-Gly for preferential binding to high and low affinity gastrin-Gly receptors.
PMID: 15949639
Ref: Gastrin 1-6 promotes growth of colon cancer cells through non-CCK receptors.
PMID: 17126952
Ref: Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.
PMID: 17188424
Ref: The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition.
PMID: 17704804
Ref: Phage display selection of fully human antibody fragments to inhibit growth-promoting effects of glycine-extended gastrin 17 on human colorectal cancer cells.
PMID: 29886758