Primary Site >> Biliary tract Cancer

Gene >> PBRM1

  • 2014
  • 2015
  • 2016
  • 2017
  • 2018
Ref: Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.
PMID: 25536104
 Ref: Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.
PMID: 25636086
Ref: Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways.
PMID: 25966424
 Ref: Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.
PMID: 26717940
Ref: Genomics of gallbladder cancer: the case for biomarker-driven clinical trial design.
PMID: 26857926
 Ref: Intrahepatic cholangiocarcinoma frequently shows loss of BAP1 and PBRM1 expression, and demonstrates specific clinicopathological and genetic characteristics with BAP1 loss.
PMID: 27864835
Ref: PBRM1 loss is a late event during the development of cholangiocarcinoma.
PMID: 28394406
 Ref: MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma.
PMID: 29113809
Ref: Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.
PMID: 29360550
Ref: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity.
PMID: 29408647
Ref: Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma.
PMID: 29551704