Primary Site >> Colorectal Cancer
Gene >> PBK
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Ref: Effects of specific active immunization on tumor recurrence following primary tumor resection in WF rats with 1,2-dimethylhydrazine-induced bowel cancer. PMID: 6590917 |
Ref: Suppression of tumor growth through introduction of an antisense plasmid of macrophage migration inhibitory factor. PMID: 12373295 Ref: [Expression of Fas genes transduced into colorectal cancer cells]. PMID: 12376253 |
Ref: Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer. PMID: 15297402 |
Ref: Serological identification of tumor antigens of esophageal squamous cell carcinoma. PMID: 15586227 |
Ref: Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells. PMID: 17631144 |
Ref: Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients. PMID: 19935791 Ref: PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21. PMID: 20622899 Ref: Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles. PMID: 20664940 |
Ref: Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. PMID: 21317303 |
Ref: Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. PMID: 22523035 |
Ref: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma. PMID: 24621249 |
Ref: CXCL8, overexpressed in colorectal cancer, enhances the resistance of colorectal cancer cells to anoikis. PMID: 25687885 |
Ref: PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth. PMID: 26936995 Ref: Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase. PMID: 26967058 Ref: Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon. PMID: 27016416 Ref: Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase. PMID: 27746693 |
Ref: miR-216b promotes cell growth and enhances chemosensitivity of colorectal cancer by suppressing PDZ-binding kinase. PMID: 28373071 Ref: Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. PMID: 28388576 Ref: The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis. PMID: 28412249 |
Ref: Targeting PRPK Function Blocks Colon Cancer Metastasis. PMID: 29483219 Ref: Cytoplasmic, nuclear, and total PBK/TOPK expression is associated with prognosis in colorectal cancer patients: A retrospective analysis based on immunohistochemistry stain of tissue microarrays. PMID: 30286126 |