Primary Site >> Stomach Cancer
Gene >> PARP1
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Ref: Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. PMID: 11146441 Ref: Inhibition of proteasome function induced apoptosis in gastric cancer. PMID: 11477551 Ref: Regulation of the new coexpressed CD55 (decay-accelerating factor) receptor on stomach carcinoma cells involved in antibody SC-1-induced apoptosis. PMID: 11706063 |
Ref: [Synergistic cytotoxic effect of immunotoxin HEL-PE38KDEL and cis-platin against tumor cells]. PMID: 12452011 Ref: Retinoic Acid Enhances Drug-Induced Cell Death in Anticancer Drug-Resistant Cell Lines. PMID: 26680865 |
Ref: Induction mechanism of apoptosis by troglitazone through peroxisome proliferator-activated receptor-gamma in gastric carcinoma cells. PMID: 12680223 |
Ref: Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis. PMID: 14604899 Ref: Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway. PMID: 14747535 Ref: Synthetic CDCA derivatives-induced apoptosis of stomach cancer cell line SNU-1 cells. PMID: 20396553 |
Ref: Modulation of anti-apoptosis by endogenous IAP expression in MKN45 human gastric cancer cells. PMID: 16080516 Ref: Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human gastric cancer (AGS) cells. PMID: 16393120 Ref: Effect of pseudolaric acid B on gastric cancer cells: inhibition of proliferation and induction of apoptosis. PMID: 16437677 Ref: Characterization of RhoA-mediated chemoresistance in gastric cancer cells. PMID: 19956523 |
Ref: [Correlation of genetic polymorphisms in DNA repair genes ADPRT and XRCC1 to risk of gastric cancer]. PMID: 16405741 Ref: Proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression. PMID: 16699947 Ref: Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus verniciflua Stokes in AGS gastric cancer cells. PMID: 16786174 Ref: Porphyran induces apoptosis related signal pathway in AGS gastric cancer cell lines. PMID: 16876203 |
Ref: Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell. PMID: 18167185 |
Ref: The effect of polysaccharide extracted from the marine alga Capsosiphon fulvescens on ethanol administration. PMID: 18524446 |
Ref: Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer. PMID: 19672268 |
Ref: Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors. PMID: 20811689 |
Ref: (-)-Epigallocatechin-3-gallate induces apoptosis in gastric cancer cell lines by down-regulating survivin expression. PMID: 21344159 Ref: Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells. PMID: 21443732 Ref: Lymph node metastasis of gastric cancer is associated with the interaction between poly (ADP-ribose) polymerase 1 and matrix metallopeptidase 2. PMID: 21612407 Ref: Protective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells. PMID: 21718595 Ref: Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways. PMID: 21786165 Ref: A novel compound, L34, induced apoptosis in human gastric cancer cells. PMID: 21897022 |
Ref: Galangin induces apoptosis in gastric cancer cells via regulation of ubiquitin carboxy-terminal hydrolase isozyme L1 and glutathione S-transferase P. PMID: 22142694 Ref: PARP1 polymorphisms increase the risk of gastric cancer in a Chinese population. PMID: 22221038 Ref: Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo. PMID: 22306340 Ref: Helicobacter pylori genotype and polymorphisms in DNA repair enzymes: where do they correlate in gastric cancer? PMID: 22374853 Ref: Overexpression of interferon regulatory factor 1 enhances chemosensitivity to 5-fluorouracil in gastric cancer cells. PMID: 22531515 Ref: Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification. PMID: 22614071 Ref: Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting betacatenin signaling. PMID: 22710759 Ref: beta,beta-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells. PMID: 22848597 Ref: ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. PMID: 22901183 Ref: Cochinchina momordica seed extract induces apoptosis and cell cycle arrest in human gastric cancer cells via PARP and p53 signal pathways. PMID: 23020228 Ref: Racial and tissue-specific cancer risk associated with PARP1 (ADPRT) Val762Ala polymorphism: a meta-analysis. PMID: 23073772 Ref: Polymorphisms of XRCC1 and ADPRT genes and risk of noncardia gastric cancer in a Chinese population: a case-control study. PMID: 23317230 |
Ref: FoxP3 inhibits proliferation and induces apoptosis of gastric cancer cells by activating the apoptotic signaling pathway. PMID: 23201402 Ref: Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines. PMID: 23206866 Ref: KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer. PMID: 23348694 Ref: Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. PMID: 23415900 Ref: Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells. PMID: 23441616 Ref: Superior antitumor activity of nanoparticle albumin-bound paclitaxel in experimental gastric cancer. PMID: 23460921 Ref: Transcriptional and post-translational regulation of Bim is essential for TGF-beta and TNF-alpha-induced apoptosis of gastric cancer cell. PMID: 23500081 Ref: RAD51C-deficient cancer cells are highly sensitive to the PARP inhibitor olaparib. PMID: 23512992 Ref: In silico identification of poly(ADP-ribose)polymerase-1 inhibitors and their chemosensitizing effects against cisplatin-resistant human gastric cancer cells. PMID: 23522835 Ref: Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress. PMID: 23536831 Ref: Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut. PMID: 23805780 Ref: Raddeanin A induces human gastric cancer cells apoptosis and inhibits their invasion in vitro. PMID: 23988447 Ref: The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer. PMID: 24042258 |
Ref: Antiinflammatory and antiproliferative effects of Rhus verniciflua Stokes in RAW264.7 cells. PMID: 24190230 Ref: Two DNA repair gene polymorphisms on the risk of gastrointestinal cancers: a meta-analysis. PMID: 24203816 Ref: Association between the PARP1 Val762Ala polymorphism and cancer risk: evidence from 43 studies. PMID: 24489833 Ref: 1,25-Dihydroxyvitamin D(3) and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells. PMID: 24573222 Ref: p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis. PMID: 24636898 Ref: Flavonoids identified from Korean Scutellaria baicalensis induce apoptosis by ROS generation and caspase activation on human fibrosarcoma cells. PMID: 24707875 Ref: Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis. PMID: 24742622 Ref: [Effect of Actinidia chinensis planch polysaccharide on the growth and apoptosis, and p-p38 expression in human gastric cancer SGC-7901 cells]. PMID: 24758086 Ref: Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines. PMID: 24841718 Ref: RRR-alpha-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-kappaB signaling pathway. PMID: 24970592 Ref: Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis. PMID: 24975047 Ref: A triterpenoid saponin from Adenophora triphylla var. japonica suppresses the growth of human gastric cancer cells via regulation of apoptosis and autophagy. PMID: 25146681 Ref: Suberoylanilide hydroxamic acid enhances the antitumor activity of oxaliplatin by reversing the oxaliplatininduced Src activation in gastric cancer cells. PMID: 25199623 Ref: PARP inhibitors target ATM+p53-defective gastric cancer. PMID: 25485492 Ref: Lobaplatin inhibits growth of gastric cancer cells by inducing apoptosis. PMID: 25516654 |
Ref: AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cell. PMID: 25456211 Ref: The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. PMID: 25521558 Ref: 3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade. PMID: 25633416 Ref: Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. PMID: 25638174 Ref: Dialysate Lavage: An Alternative Solution for Reducing the Peritoneal Implantation of Poorly Differentiated Gastric Cancer Cells. PMID: 25766749 Ref: Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells. PMID: 25767076 Ref: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. PMID: 25981581 Ref: MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells. PMID: 25998412 Ref: MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells. PMID: 26043797 Ref: Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks. PMID: 26090616 Ref: Antiproliferative activity of rosamultic acid is associated with induction of apoptosis, cell cycle arrest, inhibition of cell migration and caspase activation in human gastric cancer (SGC-7901) cells. PMID: 26220626 Ref: Design, synthesis, and anticancer evaluation of long-chain alkoxylated mono-carbonyl analogues of curcumin. PMID: 26318057 Ref: Auraptene, a Major Compound of Supercritical Fluid Extract of Phalsak (Citrus Hassaku Hort ex Tanaka), Induces Apoptosis through the Suppression of mTOR Pathways in Human Gastric Cancer SNU-1 Cells. PMID: 26351512 Ref: Esculetin induces apoptosis in human gastric cancer cells through a cyclophilin D-mediated mitochondrial permeability transition pore associated with ROS. PMID: 26388407 Ref: Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand. PMID: 26393583 Ref: Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications. PMID: 26540566 Ref: [Effect of Jianpi Yangzheng Xiaozheng Recipe on Apoptosis and Autophagy of Subcutaneous Transplanted Tumor in Nude Mice: an Experimental Study on Mechanism]. PMID: 26591369 Ref: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway. PMID: 26592508 |
Ref: The alpha7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes. PMID: 26499946 Ref: Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. PMID: 26612919 Ref: Platinum-zoledronate complex blocks gastric cancer cell proliferation by inducing cell cycle arrest and apoptosis. PMID: 26891667 Ref: Lentivirus-mediated inhibition of USP39 suppresses the growth of gastric cancer cells via PARP activation. PMID: 27175747 Ref: URI promotes gastric cancer cell motility, survival, and resistance to adriamycin in vitro. PMID: 27429854 Ref: T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death. PMID: 27537872 Ref: Active Components of Fungus Shiraia bambusiscola Can Specifically Induce BGC823 Gastric Cancer Cell Apoptosis. PMID: 27540519 Ref: Actinomycin D enhances killing of cancer cells by immunotoxin RG7787 through activation of the extrinsic pathway of apoptosis. PMID: 27601652 Ref: ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis. PMID: 27638859 Ref: Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells. PMID: 27695262 Ref: Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer. PMID: 27738318 Ref: High PARP-1 expression is associated with tumor invasion and poor prognosis in gastric cancer. PMID: 27895737 Ref: MiR-99a and MiR-491 Regulate Cisplatin Resistance in Human Gastric Cancer Cells by Targeting CAPNS1. PMID: 27994509 Ref: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines. PMID: 28459519 |
Ref: Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells. PMID: 27254419 Ref: Fas expression is downregulated in gastric cancer. PMID: 28000850 Ref: Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma. PMID: 28188923 Ref: Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice. PMID: 28374157 Ref: Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer. PMID: 28401005 Ref: Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer. PMID: 28407749 Ref: w09, a novel autophagy enhancer, induces autophagy-dependent cell apoptosis via activation of the EGFR-mediated RAS-RAF1-MAP2K-MAPK1/3 pathway. PMID: 28513279 Ref: Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment. PMID: 28736628 Ref: [Quinalizarin induces apoptosis in gastric cancer AGS cells via MAPK and Akt signaling pathway]. PMID: 28801290 Ref: Inhibition of PARP1 activity enhances chemotherapeutic efficiency in cisplatin-resistant gastric cancer cells. PMID: 28827033 Ref: Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death. PMID: 28860714 Ref: Co-targeting c-Met and DNA double-strand breaks (DSBs): Therapeutic strategies in BRCA-mutated gastric carcinomas. PMID: 28890386 Ref: Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo. PMID: 29048624 Ref: Inhibition of Topoisomerase IIalpha and Induction of Apoptosis in Gastric Cancer Cells by 19-Triisopropyl Andrographolide PMID: 29072435 |
Ref: Curcuzedoalide contributes to the cytotoxicity of Curcuma zedoaria rhizomes against human gastric cancer AGS cells through induction of apoptosis. PMID: 29102767 Ref: Peiminine serves as an adriamycin chemosensitizer in gastric cancer by modulating the EGFR/FAK pathway. PMID: 29328433 Ref: Usnic Acid Induces Cycle Arrest, Apoptosis, and Autophagy in Gastric Cancer Cells In Vitro and In Vivo. PMID: 29374767 Ref: Inhibition of CREPT restrains gastric cancer growth by regulation of cycle arrest, migration and apoptosis via ROS-regulated p53 pathway. PMID: 29402413 Ref: Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/beta-catenin/c-Myc signaling pathway in human gastric cancer cell. PMID: 29475060 Ref: Avicularin reversed multidrug-resistance in human gastric cancer through enhancing Bax and BOK expressions. PMID: 29635130 Ref: Combined treatment with PI3K inhibitor BKM120 and PARP inhibitor olaparib is effective in inhibiting the gastric cancer cells with ARID1A deficiency. PMID: 29767248 Ref: Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells. PMID: 29770446 Ref: Antitumor effects of seleno-beta-lactoglobulin (Se-beta-Lg) against human gastric cancer MGC-803 cells. PMID: 29859147 Ref: Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice. PMID: 29864961 Ref: Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint. PMID: 29954437 Ref: SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling. PMID: 29959912 Ref: Corosolic acid reduces 5FU chemoresistance in human gastric cancer cells by activating AMPK. PMID: 30015846 Ref: Rottlerin promotes autophagy and apoptosis in gastric cancer cell lines. PMID: 30015872 Ref: Dowregulation of OTX1 attenuates gastric cancer cell proliferation, migration and invasion. PMID: 30066897 Ref: Celastrus Orbiculatus Extract Potentiates The Sensitivity Of Cisplatin Via Caspase-Depenent Apoptosis In Gastric Cancer. PMID: 30205802 Ref: Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer. PMID: 30217218 Ref: Induction of apoptosis and G1 phase cell cycle arrest by Aster incisus in AGS gastric adenocarcinoma cells. PMID: 30226597 Ref: What Will We Expect From Novel Therapies to Esophageal and Gastric Malignancies? PMID: 30231398 Ref: Induction of ER Stress-Mediated Apoptosis by the Major Component 5,7,4'-Trimethoxyflavone Isolated from Kaempferia parviflora Tea Infusion. PMID: 30273054 Ref: Knockdown of RNF6 inhibits gastric cancer cell growth by suppressing STAT3 signaling. PMID: 30323630 Ref: [Aloin induces apoptosis via regulating the activation of MAPKs signaling pathway in human gastric cancer cells in vitro]. PMID: 30377097 |