Primary Site >> Biliary tract Cancer

Gene >> PARP1

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Ref: Binding of tumour necrosis factor-alpha (TNF-alpha) to TNF-RI induces caspase(s)-dependent apoptosis in human cholangiocarcinoma cell lines.
PMID: 10209503
Ref: TNF-alpha induces caspase 3 (CPP 32) dependent apoptosis in human cholangiocarcinoma cell line.
PMID: 11414450
Ref: Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.
PMID: 12587840
Ref: Inhibition of histone deacetylase for the treatment of biliary tract cancer: a new effective pharmacological approach.
PMID: 17729398
Ref: Arsenic trioxide inhibits cholangiocarcinoma cell growth and induces apoptosis.
PMID: 20012722
Ref: Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma.
PMID: 20691980
Ref: The BH3-mimetic ABT-737 targets the apoptotic machinery in cholangiocarcinoma cell lines resulting in synergistic interactions with zoledronic acid.
PMID: 20473610
Ref: Lobaplatin induces apoptosis and arrests cell cycle progression in human cholangiocarcinoma cell line RBE.
PMID: 22425181
Ref: Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition.
PMID: 24360936
Ref: XIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells.
PMID: 24603802
Ref: Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway.
PMID: 24655726
Ref: Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells.
PMID: 25383044
Ref: Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway.
PMID: 26592508
Ref: Proteasome inhibitor MG132 potentiates TRAIL-induced apoptosis in gallbladder carcinoma GBC-SD cells via DR5-dependent pathway.
PMID: 27277541