Primary Site >> Colorectal Cancer
Gene >> PARG
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Ref: Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFkappa-B pathway. PMID: 21713600 Ref: RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway. PMID: 22508044 Ref: Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation. PMID: 22918473 |
Ref: Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets. PMID: 23949281 |