Primary Site >> Colorectal Cancer

Gene >> PARG

  • 2012
  • 2013
Ref: Silencing Poly (ADP-Ribose) glycohydrolase (PARG) expression inhibits growth of human colon cancer cells in vitro via PI3K/Akt/NFkappa-B pathway.
PMID: 21713600
Ref: RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway.
PMID: 22508044
Ref: Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation.
PMID: 22918473
Ref: Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets.
PMID: 23949281