Primary Site >> Pancreatic Cancer

Gene >> P2RX7

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Ref: Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease.
PMID: 16920697
Ref: Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells.
PMID: 19540829
Ref: Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
PMID: 22287227
Ref: The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells.
PMID: 26607222
Ref: Targeting of the P2X7 receptor in pancreatic cancer and stellate cells.
PMID: 27513892
Ref: Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer.
PMID: 29228654
Ref: Activating P2X7 Receptors Increases Proliferation of Human Pancreatic Cancer Cells via ERK1/2 and JNK.
PMID: 29683976