Primary Site >> Colorectal Cancer

Gene >> NTHL1

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Ref: Human DNA glycosylases involved in the repair of oxidatively damaged DNA.
PMID: 15056851
Ref: Expression of DNA repair protein: MYH, NTH1, and MTH1 in colorectal cancer.
PMID: 15143881
Ref: Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition.
PMID: 17029639
Ref: Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3.
PMID: 18515411
Ref: Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
PMID: 18948225
Ref: A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer.
PMID: 25938944
Ref: The Mendelian colorectal cancer syndromes.
PMID: 26169059
Ref: Inherited predisposition to colorectal cancer: towards a more complete picture.
PMID: 26297796
Ref: Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
PMID: 27476653
Ref: Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
PMID: 27713038
Ref: The genetic basis of colonic adenomatous polyposis syndromes.
PMID: 28331556
Ref: A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients.
PMID: 28445943
Ref: Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort.
PMID: 28533537
Ref: Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.
PMID: 28912133
Ref: NTHL1 and MUTYH polyposis syndromes: two sides of the same coin?
PMID: 29105096
Ref: Rare loss of function variants in candidate genes and risk of colorectal cancer.
PMID: 30267214