Primary Site >> Pancreatic Cancer

Gene >> NRG1

  • 2003
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  • 2007
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  • 2015
  • 2017
  • 2018
Ref: A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
PMID: 12800145
Ref: Chromosome arm 8p and cancer: a fragile hypothesis.
PMID: 14554243
Ref: High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation.
PMID: 16636668
Ref: Expression and differential signaling of heregulins in pancreatic cancer cells.
PMID: 17096356
Ref: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.
PMID: 24521357
Ref: Prognosis Relevance of Serum Cytokines in Pancreatic Cancer.
PMID: 26346854
Ref: Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.
PMID: 28507002
Ref: NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer.
PMID: 29802158
Ref: Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer.
PMID: 29935372