Primary Site >> Liver Cancer

Gene >> NR4A1

  • 1987
  • 2001
  • 2007
  • 2011
  • 2014
  • 2015
  • 2016
  • 2017
Ref: Recent preclinical and clinical studies with the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB 3717).
PMID: 3431591
Ref: Hepatitis B virus X protein induced expression of the Nur77 gene.
PMID: 11700033
Ref: Hydroxymatairesinol and its mammalian metabolite enterolactone reduce the growth and metastasis of subcutaneous AH109A hepatomas in rats.
PMID: 17571967
Ref: Enrichment of Nur77 mediated by retinoic acid receptor beta leads to apoptosis of human hepatocellular carcinoma cells induced by fenretinide and histone deacetylase inhibitors.
PMID: 21319187
Ref: Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling.
PMID: 24646661
Ref: Bile acids regulate nuclear receptor (Nur77) expression and intracellular location to control proliferation and apoptosis.
PMID: 25232032
Ref: Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study.
PMID: 25666192
Ref: Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation.
PMID: 28240261
Ref: Orphan Nuclear Receptor TR3/Nur77 is a Specific Therapeutic Target for Hepatic Cancers.
PMID: 28798939
Ref: Expressions of Orphan Nuclear Receptor TR3/Nur77 in Chronic Hepatopathy and Its Clinical Significance.
PMID: 28856167