Primary Site >> Colorectal Cancer

Gene >> NOXA1

  • 2008
  • 2009
  • 2010
  • 2013
  • 2016
  • 2017
  • 2018
Ref: The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.
PMID: 18463161
Ref: Activation of NADPH oxidase 1 in tumour colon epithelial cells.
PMID: 18518859
Ref: Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity.
PMID: 19755710
Ref: c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells.
PMID: 20943948
Ref: Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.
PMID: 24187133
Ref: NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells.
PMID: 26781991
Ref: Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion.
PMID: 27743884
Ref: Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway.
PMID: 29262595
Ref: Identification and Characterization of a Novel NADPH Oxidase 1 (Nox1) Inhibitor That Suppresses Proliferation of Colon and Stomach Cancer Cells.
PMID: 29269607