Primary Site >> Pancreatic Cancer
Gene >> NOX4
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Ref: Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. PMID: 15155719 |
Ref: Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. PMID: 16037546 |
Ref: Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells. PMID: 16532036 |
Ref: NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases. PMID: 17983808 |
Ref: NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox. PMID: 21118808 |
Ref: The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. PMID: 22044669 |
Ref: Nox4-derived ROS signaling contributes to TGF-beta-induced epithelial-mesenchymal transition in pancreatic cancer cells. PMID: 24123012 |
Ref: Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation. PMID: 24583638 |
Ref: NADPH oxidases and cancer. PMID: 25818486 Ref: Metformin decreases growth of pancreatic cancer cells by decreasing reactive oxygen species: Role of NOX4. PMID: 26225747 |
Ref: TGF-beta1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK. PMID: 29039574 |
Ref: NOX4, A New Genetic Target for Anti-cancer Therapy in Digestive System Cancer. PMID: 30058122 |