Primary Site >> Pancreatic Cancer

Gene >> NOTCH3

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Ref: The Notch signaling pathway is related to neurovascular progression of pancreatic cancer.
PMID: 16327489
Ref: Inhibition of Notch3 enhances sensitivity to gemcitabine in pancreatic cancer through an inactivation of PI3K/Akt-dependent pathway.
PMID: 19816816
Ref: Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
PMID: 22074495
Ref: Notch3 and HEY-1 as prognostic biomarkers in pancreatic adenocarcinoma.
PMID: 23226563
Ref: Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice.
PMID: 23684930
Ref: Anti-tumor effect of the extract from qingyihuaji formula on pancreatic cancer by down-regulating Notch-4 and Jagged-1.
PMID: 25842732
Ref: Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
PMID: 25934888
Ref: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
PMID: 26279302
Ref: Transcriptomic changes associated with DKK4 overexpression in pancreatic cancer cells detected by RNA-Seq.
PMID: 26880586
Ref: The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer.
PMID: 27287498
Ref: DLL4 expression is a prognostic marker and may predict gemcitabine benefit in resected pancreatic cancer.
PMID: 27755532
Ref: LncRNA HOTAIR acts a competing endogenous RNA to control the expression of notch3 via sponging miR-613 in pancreatic cancer.
PMID: 28415631
Ref: Regulation of pancreatic stellate cell activation by Notch3.
PMID: 29304760
Ref: Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis.
PMID: 29434912
Ref: Expression of Notch receptors and their ligands in pancreatic ductal adenocarcinoma.
PMID: 29896227