Primary Site >> Biliary tract Cancer

Gene >> NOTCH2

  • 2010
  • 2012
  • 2013
  • 2014
  • 2015
  • 2017
  • 2018
Ref: Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling.
PMID: 20347808
 Ref: Expression and clinicopathological significance of notch signaling and cell-fate genes in biliary tract cancer.
PMID: 21931375
 Ref: Constitutive Notch2 signaling induces hepatic tumors in mice.
PMID: 23175466
 Ref: Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.
PMID: 25031748
 Ref: miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells.
PMID: 25769721
 Ref: Epigenetic Silencing of miRNA-34a in Human Cholangiocarcinoma via EZH2 and DNA Methylation: Impact on Regulation of Notch Pathway.
PMID: 28923203
Ref: Kras(G12D) upregulates Notch signaling to induce gallbladder tumorigenesis in mice.
PMID: 29142904
 Ref: Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans.
PMID: 29378174
Ref: Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
PMID: 29545603