Primary Site >> Stomach Cancer
Gene >> NOTCH1
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Ref: Hath1 up-regulates gastric mucin gene expression in gastric cells. PMID: 16647036 |
Ref: Notch signaling in gastrointestinal tract (review). PMID: 17143535 Ref: [Expression and significance of Notch1 and PTEN in gastric cancer]. PMID: 17991315 |
Ref: Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53. PMID: 18813803 |
Ref: Over-activated Notch-1 protects gastric carcinoma BGC-823 cells from TNFalpha-induced apoptosis. PMID: 19403345 Ref: The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. PMID: 19491270 |
Ref: Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers. PMID: 21466361 Ref: Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer. PMID: 22249198 |
Ref: Notch2-induced COX-2 expression enhancing gastric cancer progression. PMID: 21976141 Ref: Combination DLL4 with Jagged1-siRNA can enhance inhibition of the proliferation and invasiveness activity of human gastric carcinoma by Notch1/VEGF pathway. PMID: 22020917 Ref: Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression. PMID: 22581828 Ref: beta,beta-Dimethylacrylshikonin exerts antitumor activity via Notch-1 signaling pathway in vitro and in vivo. PMID: 22634048 Ref: Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression. PMID: 22691042 Ref: ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-kappaB-dependent and Notch-independent mechanism. PMID: 22781708 Ref: Epigenetic silencing of Notch signaling in gastrointestinal cancers. PMID: 23085543 Ref: [Influence of silencing Notch1 on proliferation, migration and invasion of BGC-823 gastric cancer cells]. PMID: 23268281 |
Ref: Aldehyde dehydrogenase high gastric cancer stem cells are resistant to chemotherapy. PMID: 23440340 Ref: Activation of Wnt signaling inhibits the pro-apoptotic role of Notch in gastric cancer cells. PMID: 23563575 Ref: beta -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells. PMID: 23710217 Ref: Role of Notch signaling pathway in gastric cancer pathogenesis. PMID: 23788953 Ref: Combination treatment of PD98059 and DAPT in gastric cancer through induction of apoptosis and downregulation of WNT/beta-catenin. PMID: 23792588 Ref: The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells. PMID: 24113181 |
Ref: RECK inhibits stemness gene expression and tumorigenicity of gastric cancer cells by suppressing ADAM-mediated Notch1 activation. PMID: 23881612 Ref: Differential expression of Notch1 intracellular domain and p21 proteins, and their clinical significance in gastric cancer. PMID: 24396472 Ref: Notch1 silencing inhibits proliferation and invasion in SGC7901 gastric cancer cells. PMID: 24469571 Ref: Notch1 activation is a poor prognostic factor in patients with gastric cancer. PMID: 24642622 Ref: Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions. PMID: 24724606 Ref: Gastric cancer cell growth and epithelial-mesenchymal transition are inhibited by gamma-secretase inhibitor DAPT. PMID: 24932308 Ref: Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits. PMID: 24944018 Ref: [Expression and significance of Beclin-1 in vasculogenic mimicry formation of gastric cancer]. PMID: 25070456 Ref: Novel findings about management of gastric cancer: a summary from 10th IGCC. PMID: 25083072 Ref: Role of Notch signaling pathway in gastric cancer: a meta-analysis of the literature. PMID: 25083094 Ref: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells]. PMID: 25180870 Ref: Xiaotan Sanjie decoction attenuates tumor angiogenesis by manipulating Notch-1-regulated proliferation of gastric cancer stem-like cells. PMID: 25278704 |
Ref: Notch 1 promotes cisplatin-resistant gastric cancer formation by upregulating lncRNA AK022798 expression. PMID: 25763542 Ref: Clinical Significance of NOTCH1 and NOTCH2 Expression in Gastric Carcinomas: An Immunohistochemical Study. PMID: 25954607 Ref: Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. PMID: 25998143 Ref: SIRT3 inhibits cell proliferation in human gastric cancer through down-regulation of Notch-1. PMID: 26131100 Ref: Expression of Jagged1 predicts postoperative clinical outcome of patients with gastric cancer. PMID: 26628960 Ref: Tumor Suppressor Role of miR-363-3p in Gastric Cancer. PMID: 26709677 Ref: Gastric tumor-initiating CD44(+) cells and epithelial-mesenchymal transition are inhibited by gamma-secretase inhibitor DAPT. PMID: 26722328 |
Ref: Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer. PMID: 25823029 Ref: miR-124 interacts with the Notch1 signalling pathway and has therapeutic potential against gastric cancer. PMID: 26612211 Ref: Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. PMID: 26716415 Ref: miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression. PMID: 26742429 Ref: Exome sequencing in one family with gastric- and rectal cancer. PMID: 26872740 Ref: Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis. PMID: 27049350 Ref: Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro. PMID: 27073072 Ref: Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression. PMID: 27191259 Ref: Notch1 directly induced CD133 expression in human diffuse type gastric cancers. PMID: 27489358 Ref: Clinical significance of NOTCH1 intracellular cytoplasmic domain translocation into the nucleus in gastric cancer. PMID: 27602214 Ref: High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway. PMID: 27693038 |
Ref: Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44(+) Gastric Cancer Stem Cells. PMID: 28186678 Ref: Role of human GKN1 on APP processing in gastric cancer. PMID: 28214529 Ref: Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway. PMID: 28241766 Ref: Crocodile choline from Crocodylus siamensis induces apoptosis of human gastric cancer. PMID: 28347224 Ref: AP-2alpha reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. PMID: 28439677 Ref: COX-2 regulates Snail expression in gastric cancer via the Notch1 signaling pathway. PMID: 28586004 Ref: miR-200b inhibits CD133(+) glioma cells by targeting the AKT pathway. PMID: 28599471 Ref: Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK. PMID: 28627671 Ref: Luteolin suppresses angiogenesis and vasculogenic mimicry formation through inhibiting Notch1-VEGF signaling in gastric cancer. PMID: 28655612 Ref: Suppression of midkine gene promotes the antitumoral effect of cisplatin on human gastric cancer cell line AGS in vitro and in vivo via the modulation of Notch signaling pathway. PMID: 28656262 Ref: Inhibition of Hes1 enhances lapatinib sensitivity in gastric cancer sphere-forming cells. PMID: 28959362 |
Ref: First-line treatment of apatinib in elderly patient of advanced gastric carcinoma: A case report of NGS-driven targeted therapy. PMID: 29336669 Ref: Tumor suppressive microRNA-708 targets Notch1 to suppress cell proliferation and invasion in gastric cancer. PMID: 29444743 Ref: Inverse Correlation between Methylation and Expression of the Delta-like Ligand 1 Gene in Gastric Cancer. PMID: 29526075 Ref: The function of Notch1 intracellular domain in the differentiation of gastric cancer. PMID: 29616098 Ref: Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells. PMID: 29781036 Ref: MiR-92 suppresses proliferation and induces apoptosis by targeting EP4/Notch1 axis in gastric cancer. PMID: 29849934 Ref: Autophagy regulates chemoresistance of gastric cancer stem cells via the Notch signaling pathway. PMID: 29917191 Ref: KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer. PMID: 29956735 Ref: Reversing effect of NOTCH1 inhibitor LY3039478 on drug-resistance cells SGC7901/DDP of human gastric cancer and its mechanism. PMID: 30024600 Ref: A systematic analysis of the association between Notch1 expression and the patients with digestive tract cancers. PMID: 30043645 Ref: Doxorubicin combined with Notch1-targeting siRNA for the treatment of gastric cancer. PMID: 30127866 Ref: MicroRNA-133a inhibits gastric cancer cells growth, migration, and epithelial-mesenchymal transition process by targeting presenilin 1. PMID: 30161272 Ref: Landscape of somatic mutations in gastric cancer assessed using next-generation sequencing analysis. PMID: 30250552 |