Primary Site >> Colorectal Cancer
Gene >> NOS2
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Ref: Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation. PMID: 7524602 Ref: Aberrant expression of nitric oxide synthase in human polyps, neoplastic colonic mucosa and surrounding peritumoral normal mucosa. PMID: 7525094 |
Ref: High nitric oxide synthase activity in endothelial cells in ulcerative colitis. PMID: 7550872 Ref: Involvement of a transforming-growth-factor-beta-like molecule in tumor-cell-derived inhibition of nitric-oxide synthesis in cerebral endothelial cells. PMID: 7558424 |
Ref: Nitric oxide synthase activity and expression in human colorectal cancer. PMID: 8640931 |
Ref: Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane. PMID: 9102204 Ref: Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo. PMID: 9252519 |
Ref: Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. PMID: 9443414 |
Ref: Expression of inducible nitric oxide synthase in human thyroid papillary carcinomas. PMID: 10090309 Ref: Nitric oxide synthase expression and nitric oxide production in human colon carcinoma tissue. PMID: 10219017 Ref: Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. PMID: 10223193 Ref: Expression of inducible nitric oxide synthase in tumors in relation with their regression induced by lipid A in rats. PMID: 10328229 Ref: Demonstration of iNOS-mRNA and iNOS in human monocytes stimulated with cancer cells in vitro. PMID: 10331487 Ref: Reactive nitrogen species in colon carcinogenesis. PMID: 11233144 |
Ref: Increased in situ expression of nitric oxide synthase in human colorectal cancer. PMID: 10755599 Ref: Expression of prostaglandin endoperoxide H synthase-2 induced by nitric oxide in conditionally immortalized murine colonic epithelial cells. PMID: 10834941 Ref: Intensified regression of colon cancer liver metastases in mice treated with irinotecan and the immunomodulator JBT 3002. PMID: 10838661 Ref: Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. PMID: 10910033 Ref: Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): in vitro antiproliferative effects of a COX-2 inhibitor. PMID: 10919635 Ref: Preventive potential of wheat bran fractions against experimental colon carcinogenesis: implications for human colon cancer prevention. PMID: 10987288 Ref: Cytokines secreted by lymphokine-activated killer cells induce endogenous nitric oxide synthesis and apoptosis in DLD-1 colon cancer cells. PMID: 11006006 Ref: Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression by interleukin 1beta is mediated by nitric oxide-related signalings in human colorectal cancer cells. PMID: 11025451 Ref: Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells. PMID: 11114180 Ref: Expression of inducible nitric oxide synthase in colorectal cancer and its association with prognosis. PMID: 11145294 Ref: COX-2 and iNOS, good targets for chemoprevention of colon cancer. PMID: 11216473 Ref: Recent studies on the biofunctions and biotransformations of curcumin. PMID: 11237176 |
Ref: Modulation of inducible nitric oxide synthase expression in rat intestinal cells by colon tumor promoters. PMID: 11115551 Ref: The physiological expression of inducible nitric oxide synthase (iNOS) in the human colon. PMID: 11304846 Ref: Mechanisms of cancer chemoprevention by curcumin. PMID: 11370761 Ref: Nitric oxide synthase as a marker in colorectal carcinoma. PMID: 11450795 Ref: Influence of the ward colon tumor on the innate and endotoxin-induced inflammatory response of the rat. PMID: 11577811 Ref: Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer. PMID: 11705852 Ref: Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status. PMID: 11713587 |
Ref: Microencapsulated iNOS-expressing cells cause tumor suppression in mice. PMID: 11772948 Ref: Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor. PMID: 11782374 Ref: Suppression of promoter-dependent transcriptional activity of inducible nitric oxide synthase by sodium butyrate in colon cancer cells. PMID: 11825662 Ref: Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver. PMID: 11880186 Ref: Immunohistochemical expression of cytokine induced nitric oxide synthase in colorectal carcinoma. PMID: 11956620 Ref: Red wine and black tea polyphenols modulate the expression of cycloxygenase-2, inducible nitric oxide synthase and glutathione-related enzymes in azoxymethane-induced f344 rat colon tumors. PMID: 12042461 Ref: Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis. PMID: 12064512 Ref: Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine. PMID: 12082021 Ref: Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells. PMID: 12415733 Ref: Modulation of CYP3A4 expression by ceramide in human colon carcinoma HT-29 cells. PMID: 12419308 Ref: Doxorubicin inhibits the production of nitric oxide by colorectal cancer cells. PMID: 12433207 Ref: Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. PMID: 12496057 |
Ref: Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis. PMID: 12598314 Ref: Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. PMID: 12615711 Ref: Overexpression of the human inducible nitric oxide synthase gene enhances radiation-induced apoptosis in colorectal cancer cells via a caspase-dependent mechanism. PMID: 12620375 Ref: Chemoprevention of colon cancer by Korean food plant components. PMID: 12628507 Ref: Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. PMID: 12684662 Ref: Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. PMID: 12702049 Ref: Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines. PMID: 12727790 Ref: Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence. PMID: 12800233 Ref: Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice. PMID: 14524534 Ref: Transfection of K-rasAsp12 cDNA markedly elevates IL-1beta- and lipopolysaccharide-mediated inducible nitric oxide synthase expression in rat intestinal epithelial cells. PMID: 14576830 Ref: A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. PMID: 14611673 Ref: Aberrant crypt foci as microscopic precursors of colorectal cancer. PMID: 14669304 |
Ref: S-Nitrosation regulates the activation of endogenous procaspase-9 in HT-29 human colon carcinoma cells. PMID: 14701803 Ref: Expression of beta-catenin, COX-2 and iNOS in colorectal cancer: relevance of COX-2 adn iNOS inhibitors for treatment in Malaysia. PMID: 14719508 Ref: Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity. PMID: 14973054 Ref: Nitric oxide differentially regulates pro- and anti-angiogenic markers in DLD-1 colon carcinoma cells. PMID: 15063730 Ref: [Influence of sodium butyrate on growth of HT-29 colon carcinoma cells and expression of inducible nitric oxide synthase (iNOS)]. PMID: 15087030 Ref: Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer. PMID: 15102673 Ref: Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. PMID: 15132774 Ref: Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents. PMID: 15182426 Ref: Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease. PMID: 15199542 Ref: Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention. PMID: 15199544 Ref: Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway. PMID: 15314290 Ref: Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide. PMID: 15476266 Ref: Nitric oxide signaling in colon cancer chemoprevention. PMID: 15476855 Ref: Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53. PMID: 15520210 Ref: Carcinoembryonic antigen promotes tumor cell survival in liver through an IL-10-dependent pathway. PMID: 16035616 |
Ref: Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cycloox PMID: 15459021 Ref: Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis. PMID: 15695237 Ref: Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor. PMID: 15713431 Ref: Hemin potentiates nitric oxide-mediated nitrosation of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) to 2-nitrosoamino-3-methylimidazo[4,5-f]quinoline. PMID: 15777093 Ref: Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis. PMID: 15785755 Ref: Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. PMID: 15892897 Ref: Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans. PMID: 15905073 Ref: Nitric oxide synthase 2 (NOS2) promoter polymorphisms in colorectal cancer. PMID: 15922861 Ref: Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis. PMID: 16049281 Ref: NO-donating aspirin inhibits both the expression and catalytic activity of inducible nitric oxide synthase in HT-29 human colon cancer cells. PMID: 16105666 Ref: The RNA binding protein TIAR is involved in the regulation of human iNOS expression. PMID: 16191398 Ref: Impact of Mycoplasma hyorhinis infection on L-arginine metabolism: differential regulation of the human and murine iNOS gene. PMID: 16218877 Ref: Effect of a nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on invasion of human colorectal cancer cell line SL-174T. PMID: 16419170 |
Ref: Suppressive effect of an inducible nitric oxide inhibitor, ONO-1714, on AOM-induced rat colon carcinogenesis. PMID: 16122953 Ref: Increased protein expression of both inducible nitric oxide synthase and cyclooxygenase-2 in human colon cancers. PMID: 16216410 Ref: The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis. PMID: 16329147 Ref: Suppression of colon carcinogenesis by bioactive compounds in grapefruit. PMID: 16387741 Ref: Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. PMID: 16395701 Ref: Aberrant crypt foci. PMID: 16475686 Ref: Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets. PMID: 16818512 Ref: Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation. PMID: 16904962 Ref: Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation. PMID: 16928387 Ref: Expression of NOS and HIF-1alpha in human colorectal carcinoma and implication in tumor angiogenesis. PMID: 16937436 Ref: Effects of quercetin and beta-carotene supplementation on azoxymethane-induced colon carcinogenesis and inflammatory responses in rats fed with high-fat diet rich in omega-6 fatty acids. PMID: 17012770 Ref: Polymorphisms within inflammatory genes and colorectal cancer. PMID: 17062130 Ref: Mild inflammation accelerates colon carcinogenesis in Mlh1-deficient mice. PMID: 17347588 |
Ref: Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival. PMID: 17096347 Ref: The use of nitric oxide-donating nonsteroidal anti-inflammatory drugs in the chemoprevention of colorectal neoplasia. PMID: 17133086 Ref: Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. PMID: 17178380 Ref: Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats. PMID: 17200374 Ref: Colorectal carcinoma development in inducible nitric oxide synthase-deficient mice with dextran sulfate sodium-induced ulcerative colitis. PMID: 17219424 Ref: Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells. PMID: 17277882 Ref: Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models. PMID: 17371270 Ref: A specific inducible nitric oxide synthase inhibitor, ONO-1714 attenuates inflammation-related large bowel carcinogenesis in male Apc(Min/+) mice. PMID: 17417780 Ref: The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells. PMID: 17438334 Ref: Human osteocalcin: a strong promoter for nitric oxide synthase gene therapy, with specificity for hormone refractory prostate cancer. PMID: 17471586 Ref: Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo. PMID: 17699720 Ref: Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. PMID: 17721042 Ref: Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions. PMID: 17723178 Ref: Inhibitory effect of phytoglycoprotein on tumor necrosis factor-alpha and interleukin-6 at initiation stage of colon cancer in 1,2-dimethylhydrazine-treated ICR mice. PMID: 17868752 Ref: Novel agents for cancer prevention based on nitric oxide. PMID: 17956352 Ref: Inhibition of proinflammatory cytokine-induced invasiveness of HT-29 cells by chitosan oligosaccharide. PMID: 18167453 |
Ref: PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor. PMID: 17637826 Ref: Chemopreventive effect of plant originated glycoprotein on colitis-mediated colorectal cancer in A/J mice. PMID: 17657586 Ref: Protective effects of vanadium against DMH-induced genotoxicity and carcinogenesis in rat colon: removal of O(6)-methylguanine DNA adducts, p53 expression, inducible nitric oxide synthase downregulation and apoptotic induction. PMID: 18155637 Ref: The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary tumor t PMID: 18321443 Ref: Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. PMID: 18339887 Ref: Chemoprevention of colon carcinogenesis by oleanolic acid and its analog in male F344 rats and modulation of COX-2 and apoptosis in human colon HT-29 cancer cells. PMID: 18408893 Ref: [Effect of a selective inducible nitric oxide synthase inhibitor on cell growth in human colorectal cancer Lovo cell line]. PMID: 18478477 Ref: Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase. PMID: 18485715 Ref: Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. PMID: 18567620 |
Ref: Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer. PMID: 19005184 Ref: Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis. PMID: 19056647 Ref: Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice. PMID: 19164562 Ref: Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells. PMID: 19383900 Ref: [The design, synthesis and anticancer activity of 4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS]. PMID: 19449526 Ref: Anti-inflammatory effect of coumarins isolated from Corydalis heterocarpa in HT-29 human colon carcinoma cells. PMID: 19500635 Ref: Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. PMID: 19737943 Ref: iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells. PMID: 19925669 Ref: Xanthorrhizol, a natural sesquiterpenoid, induces apoptosis and growth arrest in HCT116 human colon cancer cells. PMID: 19926935 Ref: Quercetin Suppresses Early Colon Carcinogenesis Partly through Inhibition of Inflammatory Mediators. PMID: 20396589 |
Ref: Heterogeneous expression of cyclooxygenase-2 and inducible nitric oxide synthase within colorectal tumors: correlation with tumor angiogenesis. PMID: 19497798 Ref: Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. PMID: 20027603 Ref: Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice. PMID: 20072658 Ref: Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. PMID: 20096072 Ref: Inducible nitric oxide synthase expression and its prognostic significance in colorectal cancer. PMID: 20132175 Ref: Inhibition of TNFalpha-induced iNOS expression in HSV-tk transduced 9L glioblastoma cell lines by Marasmius oreades substances through NF-kappaB- and MAPK-dependent mechanisms. PMID: 20224909 Ref: Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. PMID: 20360625 Ref: Antitumor and antimetastatic effects of licochalcone A in mouse models. PMID: 20383690 Ref: Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. PMID: 20406206 Ref: Extra-virgin olive oil-enriched diet modulates DSS-colitis-associated colon carcinogenesis in mice. PMID: 20427102 Ref: Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. PMID: 20459814 Ref: Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats. PMID: 20511675 Ref: Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract. PMID: 20522643 Ref: Substance P and vasoactive intestinal peptide are reduced in right transverse colon in pediatric slow-transit constipation. PMID: 20529207 Ref: Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction. PMID: 20542496 Ref: Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats. PMID: 20564341 Ref: Regular exercise reduces colon tumorigenesis associated with suppression of iNOS. PMID: 20633535 Ref: Role of phenolic compounds in nitric oxide synthase activity in colon and breast adenocarcinoma. PMID: 20874429 |
Ref: Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis. PMID: 20722052 Ref: Anti-inflammatory/Anti-oxidative stress activities and differential regulation of Nrf2-mediated genes by non-polar fractions of tea Chrysanthemum zawadskii and licorice Glycyrrhiza uralensis. PMID: 20967519 Ref: p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells. PMID: 21353507 Ref: Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway. PMID: 21355597 Ref: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity. PMID: 21586136 Ref: Nitric Oxide (NO) and Cyclooxygenase-2 (COX-2) Cross-Talk in Co-Cultures of Tumor Spheroids with Normal Cells. PMID: 21909878 |
Ref: A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. PMID: 21919080 Ref: Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice. PMID: 22159228 Ref: Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. PMID: 22231745 Ref: Anti-inflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-kappaB activation in Caco-2 and SW480 human colon cancer cells. PMID: 22251620 Ref: Thrombospondin-1 and VEGF in inflammatory bowel disease. PMID: 22299021 Ref: Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/beta-catenin signaling. PMID: 22397759 Ref: The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans. PMID: 22417974 Ref: Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways. PMID: 22419013 Ref: Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. PMID: 22517765 Ref: Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes. PMID: 22531693 Ref: IL1beta-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells. PMID: 22884582 Ref: Dietary administration of scallion extract effectively inhibits colorectal tumor growth: cellular and molecular mechanisms in mice. PMID: 23024755 Ref: The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer. PMID: 23077543 Ref: Amelioration of 1,2 Dimethylhydrazine (DMH) induced colon oxidative stress, inflammation and tumor promotion response by tannic acid in Wistar rats. PMID: 23167349 Ref: Inhibitory effects of meju prepared with mixed starter cultures on azoxymethane and dextran sulfate sodium-induced colon carcinogenesis in mice. PMID: 23230391 Ref: Molecular docking studies of quercetin and its analogues against human inducible nitric oxide synthase. PMID: 23556141 Ref: Chemoprevention of Colon Cancer by iNOS-Selective Inhibitors. PMID: 23678395 |
Ref: Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-kappaB signaling. PMID: 22086675 Ref: IFNalpha converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets. PMID: 23153456 Ref: Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis. PMID: 23233214 Ref: Bamboo salt has in vitro anticancer activity in HCT-116 cells and exerts anti-metastatic effects in vivo. PMID: 23256441 Ref: Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells. PMID: 23348408 Ref: Natural antisense transcript-targeted regulation of inducible nitric oxide synthase mRNA levels. PMID: 23348570 Ref: Hesperidin alleviates oxidative stress and downregulates the expressions of proliferative and inflammatory markers in azoxymethane-induced experimental colon carcinogenesis in mice. PMID: 23377175 Ref: Antioxidant rich Morus alba leaf extract induces apoptosis in human colon and breast cancer cells by the downregulation of nitric oxide produced by inducible nitric oxide synthase. PMID: 23441618 Ref: Identification of patients with developing ulcerative colitis-associated neoplasia by nitrative DNA damage marker 8-nitroguanin expression in rectal mucosa. PMID: 23632356 Ref: Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. PMID: 23639480 Ref: Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats. PMID: 23708609 Ref: Elevated incidence of polyp formation in APC(Min/(+))Msh2(-)/(-) mice is independent of nitric oxide-induced DNA mutations. PMID: 23741483 Ref: Ilex kudingcha C.J. Tseng (Kudingcha) has in vitro anticancer activities in MCF-7 human breast adenocarcinoma cells and exerts anti-metastatic effects in vivo. PMID: 23760150 Ref: Bimodal role of Kupffer cells during colorectal cancer liver metastasis. PMID: 23792646 Ref: Anti-inflammatory effects of kudingcha methanol extract (Ilex kudingcha C.J. Tseng) in dextran sulfate sodium-induced ulcerative colitis. PMID: 23969782 Ref: Protection from inflammatory bowel disease and colitis-associated carcinogenesis with 4-vinyl-2,6-dimethoxyphenol (canolol) involves suppression of oxidative stress and inflammatory cytokines. PMID: 24064222 Ref: Dietary non-nutritive factors in targeting of regulatory molecules in colorectal cancer: an update. PMID: 24289544 Ref: [Physical activity in prevention and treatment of colon cancer]. PMID: 24697040 |
Ref: iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells. PMID: 24420967 Ref: Raloxifene and antiestrogenic gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem-like cells. PMID: 24431404 Ref: Changes chemopreventive markers in colorectal cancer development after inulin supplementation. PMID: 24601699 Ref: Demethoxycurcumin from Curcuma longa rhizome suppresses iNOS induction in an in vitro inflamed human intestinal mucosa model. PMID: 24641413 Ref: Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. PMID: 24837432 Ref: Exercise effects on polyp burden and immune markers in the ApcMin/+ mouse model of intestinal tumorigenesis. PMID: 24859893 Ref: Anti-inflammatory effects of betaine on AOM/DSSinduced colon tumorigenesis in ICR male mice. PMID: 24969167 Ref: Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2. PMID: 24991108 Ref: [Chemo-preventive effect of Angelica sinensis' supercritical extracts on AOM/DSS-induced mouse colorectal carcinoma associated with inflammation]. PMID: 25011266 Ref: Decoding the s-nitrosoproteomic atlas in individualized human colorectal cancer tissues using a label-free quantitation strategy. PMID: 25040305 Ref: Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice. PMID: 25218594 Ref: D. candidum has in vitro anticancer effects in HCT-116 cancer cells and exerts in vivo anti-metastatic effects in mice. PMID: 25324926 Ref: Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils. PMID: 25347345 Ref: The influence of the CHIEF pathway on colorectal cancer-specific mortality. PMID: 25541970 |
Ref: Targeting colon cancer cell NF-kappaB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis. PMID: 24704833 Ref: Utility of Apc-mutant rats with a colitis-associated colon carcinogenesis model for chemoprevention studies. PMID: 25222193 Ref: Helicobacter cinaedi induced typhlocolitis in Rag-2-deficient mice. PMID: 25381744 Ref: Effect of Cnidii Rhizoma on nitric oxide production and invasion of human colorectal adenocarcinoma HT-29 cells. PMID: 25436013 Ref: Loss of p53 in stromal fibroblasts enhances tumor cell proliferation through nitric-oxide-mediated cyclooxygenase 2 activation. PMID: 25511472 Ref: Dietary cocoa protects against colitis-associated cancer by activating the Nrf2/Keap1 pathway. PMID: 25545372 Ref: Advances in radiotherapy delivery for rectal cancer: a European perspective. PMID: 25644307 Ref: Poly-gamma-glutamic acid induces apoptosis via reduction of COX-2 expression in TPA-induced HT-29 human colorectal cancer cells. PMID: 25854428 Ref: Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer. PMID: 25869209 Ref: High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells. PMID: 25875314 Ref: Carvacrol exhibits anti-oxidant and anti-inflammatory effects against 1, 2-dimethyl hydrazine plus dextran sodium sulfate induced inflammation associated carcinogenicity in the colon of Fischer 344 rats. PMID: 25881504 Ref: P53-dependent miRNAs mediate nitric oxide-induced apoptosis in colonic carcinogenesis. PMID: 25912478 Ref: Curcumin ameliorates the tumor-enhancing effects of a high-protein diet in an azoxymethane-induced mouse model of colon carcinogenesis. PMID: 26094212 Ref: Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice. PMID: 26196182 Ref: Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer. PMID: 26205949 Ref: Brewers' rice modulates oxidative stress in azoxymethane-mediated colon carcinogenesis in rats. PMID: 26269672 Ref: Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms. PMID: 26319951 Ref: Dual biological functions of the apoptotic activity and anti-inflammatory effect by alcyonolide congeners from the Okinawan soft coral, Cespitularia sp. PMID: 26351041 Ref: The NF-kappaB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription. PMID: 26497740 Ref: Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions. PMID: 26503803 Ref: Mulberry fruit prevents LPS-induced NF-kappaB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. PMID: 26615818 Ref: DOWN-REGULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION BY INOSITOL HEXAPHOSPHATE IN HUMAN COLON CANCER CELLS. PMID: 26647627 Ref: Effect of camptothecin on inducible nitric oxide synthase expression in the colon cancer SW480 cell line. PMID: 26722304 Ref: Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition. PMID: 26793111 |
Ref: Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells. PMID: 26259065 Ref: Quantitative measurement of iNOS expression in melanoma, nasopharyngeal, colorectal, and breast tumors of Tunisian patients: comparative study and clinical significance. PMID: 26547585 Ref: Regulation of colorectal cancer cell epithelial to mesenchymal transition by the renin angiotensin system. PMID: 26849969 Ref: Paricalcitol Enhances the Chemopreventive Efficacy of 5-Fluorouracil on an Intermediate-Term Model of Azoxymethane-Induced Colorectal Tumors in Rats. PMID: 27020656 Ref: The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice. PMID: 27207670 Ref: Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties. PMID: 27447967 Ref: Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats. PMID: 27468227 Ref: T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells. PMID: 27622331 Ref: Different Susceptibilities between Apoe- and Ldlr-Deficient Mice to Inflammation-Associated Colorectal Carcinogenesis. PMID: 27801847 Ref: Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation. PMID: 27876107 Ref: Colorectal cancer in Iran: Epidemiology and morphology trends. PMID: 28337105 |
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