Primary Site >> Colorectal Cancer

Gene >> NME2

  • 1993
  • 1995
  • 1997
  • 2001
  • 2003
  • 2004
  • 2005
  • 2010
  • 2014
  • 2017
  • 2018
Ref: Mutation in the nm23 gene is associated with metastasis in colorectal cancer.
PMID: 7916650
Ref: Localization of a second NM23 gene, NME2, to chromosome 17q21-q22.
PMID: 8406509
Ref: Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
PMID: 8418304
 Ref: [Correlation study of allelic gene deletion of nm23-H1 and human colorectal carcinoma metastasis].
PMID: 7587891
Ref: Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.
PMID: 7734302
Ref: Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages.
PMID: 8549951
 Ref: Isolation and characterization of new microsatellites at the nm23-H1 and nm23-H2 gene loci and application for loss of heterozygosity (LOH) analysis.
PMID: 9341864
 Ref: Overexpression of nm23-H4 RNA in colorectal and renal tumours.
PMID: 11724361
 Ref: Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer.
PMID: 12678475
 Ref: Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue.
PMID: 15079086
 Ref: Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
PMID: 15726650
Ref: Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.
PMID: 15814641
Ref: Identification of proteins from colorectal cancer tissue by two-dimensional gel electrophoresis and SELDI mass spectrometry.
PMID: 15942672
 Ref: Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
PMID: 20841469
 Ref: Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions.
PMID: 24444821
 Ref: Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion.
PMID: 28717007
 Ref: Nucleoside diphosphate kinase 2 confers acquired 5-fluorouracil resistance in colorectal cancer cells.
PMID: 29475390