Primary Site >> Colorectal Cancer
Gene >> NME1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma. PMID: 1679868 Ref: A genetic basis for metastasis. PMID: 1802402 Ref: Somatic allelic deletion of nm23 in human cancer. PMID: 2015608 Ref: Induction of nm23 gene expression in human colonic neoplasms and equal expression in colon tumors of high and low metastatic potential. PMID: 2023273 |
Ref: Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms. PMID: 1394207 |
Ref: Mutation in the nm23 gene is associated with metastasis in colorectal cancer. PMID: 7916650 Ref: Reduced expression of nm23 protein is associated with advanced tumor stage and distant metastases in human colorectal carcinomas. PMID: 8099459 Ref: Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis. PMID: 8217591 Ref: Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer. PMID: 8297127 Ref: High levels of Nm23 gene expression in advanced stage of thyroid carcinomas. PMID: 8394105 Ref: Localization of a second NM23 gene, NME2, to chromosome 17q21-q22. PMID: 8406509 Ref: Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential. PMID: 8418304 |
Ref: [Metastasis-related genes]. PMID: 7526801 Ref: Positive relationship between expression of CD44 and hepatic metastases in colorectal cancer. PMID: 7537507 Ref: Dinucleotide repeat polymorphisms at nine loci in sporadic colorectal cancer. PMID: 7787886 Ref: The role of nm23 in transforming growth factor beta 1-mediated adherence and growth arrest. PMID: 7819128 Ref: High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases. PMID: 7947079 Ref: Frequency of allele loss of DCC, p53, RBI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. PMID: 7947085 Ref: Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer. PMID: 7981087 Ref: Isolation of human nm23 genomes and analysis of loss of heterozygosity in primary colorectal carcinomas using a specific genomic probe. PMID: 8033126 Ref: Loss of heterozygosity of tumour suppressor gene loci in human colorectal carcinoma. PMID: 8080684 Ref: Isolation and characterization of the promoter region of human nm23-H1, a metastasis suppressor gene. PMID: 8084595 Ref: Nm23 'anti-metastatic' gene product expression in colorectal carcinoma. PMID: 8195929 Ref: Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas. PMID: 8199988 Ref: Expression of nm23 H-1 RNA levels in human gastric cancer tissues. A negative correlation with nodal metastasis. PMID: 8293386 Ref: The Nm23 gene and colorectal cancer. PMID: 8307441 |
Ref: Colon carcinoma cells with inactive nm23 show increased motility and response to motility factors. PMID: 7554087 Ref: [Correlation study of allelic gene deletion of nm23-H1 and human colorectal carcinoma metastasis]. PMID: 7587891 Ref: Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region. PMID: 7734302 Ref: Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma. PMID: 7774480 Ref: Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages. PMID: 8549951 Ref: Overexpression of NDP kinase nm23 associated with ploidy image analysis in colorectal cancer. PMID: 8572601 Ref: [nm23 gene product/NDPK expression and its clinical significance in human colorectal carcinoma]. PMID: 8732091 |
Ref: Allelic imbalance at NME1 in microdissected primary and metastatic human colorectal carcinomas is frequent but not associated with metastasis to lymph nodes or liver. PMID: 8631033 Ref: nm23 expression in advanced and borderline ovarian carcinoma. PMID: 8702236 Ref: Increased levels of nm23 H1/nucleoside diphosphate kinase A mRNA associated with adenocarcinoma of the prostate. PMID: 8738406 Ref: [Principles of lymphogenic and hematogenous metastasis and metastasis classification]. PMID: 8767327 Ref: NM-23 H1 immunohistochemistry is not useful as predictor of metastatic potential of colorectal cancer. PMID: 8912537 |
Ref: The significance of allelic deletions and aneuploidy in colorectal carcinoma. Results of a 5-year follow-up study. PMID: 9010096 Ref: Early stage human colorectal cancer: prognostic value of nm23-H1 protein overexpression. PMID: 9022121 Ref: Assessment of microsatellite alterations in young patients with gastric adenocarcinoma. PMID: 9024705 Ref: The prediction of lymph node metastases in colorectal cancer by expression of the nucleoside diphosphate kinase/nm23-H1 and histopathological variables. PMID: 9219795 Ref: Isolation and characterization of new microsatellites at the nm23-H1 and nm23-H2 gene loci and application for loss of heterozygosity (LOH) analysis. PMID: 9341864 Ref: [The role of nm23 protein in progression of sporadic adenocarcinoma of the large intestine]. PMID: 9446409 |
Ref: NM23 gene product expression does not predict lymph node metastases or survival in young patients with colorectal cancer. PMID: 9538187 Ref: Nm23 gene expression in gastric carcinoma: an immunohistochemical study. PMID: 9563444 Ref: Overexpression of nm23 protein assessed by color video image analysis in metastatic colorectal cancer: correlation with reduced patient survival. PMID: 9564293 Ref: NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas. PMID: 9569056 Ref: Correlates of urokinase-type plasminogen activator in colorectal cancer: positive relationship with nm23 and c-erbB-2 protein expression. PMID: 9613457 Ref: Genetic instability, p53 and nm23 mutation and clinicopathological features in rectal carcinoma. PMID: 9615752 Ref: Expression of nm23 in gastric carcinoma: association with tumor progression and poor prognosis. PMID: 9874452 |
Ref: Protein markers in colorectal cancer: predictors of liver metastasis. PMID: 10450731 Ref: p27(kipl) protein expression: an independent prognostic factor in rectal carcinoma stages I-III. PMID: 23574593 |
Ref: Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma. PMID: 10664249 Ref: Genomic alterations (LOH, MI) on chromosome 17q21-23 and prognosis of sporadic colorectal cancer. PMID: 10719723 Ref: Use of crypt isolation to determine loss of heterozygosity of multiple tumor suppressor genes in colorectal carcinoma. PMID: 10729918 Ref: [Expression of nm23 protein and estrogen receptor and prognosis of colorectal cancers]. PMID: 11832096 |
Ref: Reappraisal of the role of NM23-H1 in colorectal cancers. PMID: 11223826 Ref: nm23 protein expression in colorectal carcinoma metastasis in regional lymph nodes and the liver. PMID: 11289754 Ref: nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression. PMID: 11337376 Ref: Application of the National Cancer Institute international criteria for determination of microsatellite instability in ovarian cancer. PMID: 11389062 Ref: Overexpression of nm23-H4 RNA in colorectal and renal tumours. PMID: 11724361 Ref: [Expression of cytokeratin 7 and 20 in ovarian metastatic carcinomas]. PMID: 11866966 |
Ref: Prediction of distant metastases after curative surgery for rectal cancer. PMID: 11855920 Ref: RER and LOH association with sporadic colorectal cancer in Taiwanese patients. PMID: 12063967 Ref: NM23 expression as prognostic factor in colorectal carcinoma. PMID: 12109225 Ref: Prognostic implication of nm23-H1 expression in colorectal carcinomas. PMID: 12408341 Ref: DNA ploidy and S-phase fraction, but not p53 or NM23-H1 expression, predict outcome in colorectal cancer patients. Result of a 5-year prospective study. PMID: 12474051 Ref: [Prognostic markers of the epithelial tumors of the large intestine]. PMID: 12820582 |
Ref: Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer. PMID: 12678475 Ref: [Overexpression of c-erbB-2 and hypoexpression of nm23 relating to poor prognosis of colorectal carcinoma]. PMID: 12839671 Ref: CD44v6 and Nm23-H1 protein expression related to clinico pathological parameters in colorectal cancer. PMID: 12870281 Ref: Nm23-H1 expression does not predict clinical survival in colorectal cancer patients. PMID: 12883690 Ref: Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2. PMID: 12922171 Ref: [Expression of nm23 and c-erbB-2 proteins in cells of primary colorectal cancer and its metastases]. PMID: 14664140 |
Ref: nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation. PMID: 14639604 Ref: Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. PMID: 14973550 Ref: The replication error phenotype is associated with the development of distant metastases in hormonally treated patients with breast carcinoma. PMID: 14983485 Ref: Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue. PMID: 15079086 Ref: Targets of 17beta-oestradiol-induced apoptosis in colon cancer cells: a mechanism for the protective effects of hormone replacement therapy? PMID: 15128281 Ref: Prognostic significance of nm23 gene product expression in patients with colorectal carcinoma treated with radical intent. PMID: 15138555 Ref: Systematic review of genetic influences on the prognosis of colorectal cancer. PMID: 15382104 Ref: APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia. PMID: 15507235 Ref: nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma. PMID: 15563674 |
Ref: Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer. PMID: 15726650 Ref: Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. PMID: 15814641 Ref: [Study on the prognostic factors of colorectal cancer after radical resection and on suggested model for prediction]. PMID: 15941514 Ref: [Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]. PMID: 16078572 Ref: Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. PMID: 16166432 |
Ref: Findings on 18F-FDG PET scans after neoadjuvant chemoradiation provides prognostic stratification in patients with locally advanced rectal carcinoma subsequently treated by radical surgery. PMID: 16391182 Ref: The intratumoral microvessel density and expression of bFGF and nm23-H1 in colorectal cancer. PMID: 16554912 Ref: [Lymph node micrometastases and expression of metastasis-related gene proteins in patients with colorectal cancer]. PMID: 16635348 Ref: Influence of the c-erb B-2, nm23, bcl-2 and p53 protein markers on colorectal cancer. PMID: 16830272 |
Ref: Does immunostaining effectively upstage colorectal cancer by identifying micrometastatic nodal disease? PMID: 16528541 Ref: Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray. PMID: 17278192 Ref: Clinical significance of nm23 gene expression in gastric cancer. PMID: 17695492 Ref: Identification of gene signatures for invasive colorectal tumor cells. PMID: 17936523 Ref: Understanding h-prune biology in the fight against cancer. PMID: 17952613 |
Ref: Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry. PMID: 18575723 |
Ref: Identification of S100A8 and S100A9 as serological markers for colorectal cancer. PMID: 19186948 Ref: [Effects of allicin on invasion and metastasis of colon cancer LoVo cell line in vitro]. PMID: 19671326 |
Ref: Maspin and Nm23-H1 expression in colorectal cancer. PMID: 20099971 Ref: Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. PMID: 20841469 Ref: NM23 protein expression in colorectal carcinoma using TMA (tissue microarray): association with metastases and survival. PMID: 21225146 Ref: [Adenovirus-mediated delivery of nm23-H1 gene inhibits growth of colorectal carcinoma cell line Lovo]. PMID: 21374989 |
Ref: Identification of potential pharmacogenomic markers of clinical efficacy of 5-fluorouracil in colorectal cancer. PMID: 20560137 Ref: Tissue microarrays in Chinese human rectal cancer: study of expressions of the tumor-associated genes. PMID: 22024062 Ref: Influences of laparoscopic resection on expressions of metastasis genes in colorectal cancer: report of microarray analysis and literature review. PMID: 22024071 |
Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. PMID: 22240480 Ref: [NM23, an example of a metastasis suppressor gene]. PMID: 22429909 Ref: The role of nm23 gene in colorectal carcinogenesis. PMID: 22920000 Ref: Multivariate analysis of molecular indicators for postoperative liver metastasis in colorectal cancer cases. PMID: 23098501 |
Ref: Immunohistochemical expression and significance of NM23 suppressor protein in primary gastric adenocarcinoma. PMID: 23725501 Ref: Spinophilin loss correlates with poor patient prognosis in advanced stages of colon carcinoma. PMID: 23729363 Ref: [Expression and clinical significance of vascular endothelial growth factor-C and nm23-H1 in stage II and III colorectal carcinomas]. PMID: 24119904 |
Ref: Correlation between non-metastatic protein 23 expression and clinicopathological features of colorectal cancer in Asians. PMID: 26634527 |
Ref: Reduced NM23 Protein Level Correlates With Worse Clinicopathologic Features in Colorectal Cancers: A Meta-Analysis of Pooled Data. PMID: 26825905 Ref: Evaluation of serum nucleoside diphosphate kinase A for the detection of colorectal cancer. PMID: 27222072 Ref: Insights into the potential of picoplanktonic marine cyanobacteria strains for cancer therapies - Cytotoxic mechanisms against the RKO colon cancer cell line. PMID: 27242042 Ref: Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma. PMID: 27330777 Ref: Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein. PMID: 27449069 |
Ref: Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma. PMID: 27888614 Ref: The role of NM23 in patients with colorectal cancer: A systematic review and meta-analysis. PMID: 28224416 Ref: A transcriptome-based protein network that identifies new therapeutic targets in colorectal cancer. PMID: 28962550 |
Ref: Proteomic Profiling for Colorectal Cancer Biomarker Discovery. PMID: 29589313 |