Primary Site >> Colorectal Cancer
Gene >> NEU3
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Ref: Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression. PMID: 12149448 |
Ref: Colon cancer: genomics and apoptotic events. PMID: 15255176 |
Ref: Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling. PMID: 16241905 |
Ref: Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers. PMID: 17270019 |
Ref: Protein sialylation by sialyltransferase involves radiation resistance. PMID: 18708363 |
Ref: Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice. PMID: 19215228 |
Ref: Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides. PMID: 21895867 |
Ref: Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase. PMID: 22815940 |
Ref: Sialidase NEU3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating Wnt signaling. PMID: 25810027 Ref: NEU3 activity enhances EGFR activation without affecting EGFR expression and acts on its sialylation levels. PMID: 25922362 Ref: Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease. PMID: 26401073 |
Ref: Deregulation of sialidases in human normal and tumor tissues. PMID: 29278877 |