Primary Site >> Stomach Cancer
Gene >> NELFCD
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Ref: Augmentation of immune response by an analog of the antigenic peptide in a human T-cell clone recognizing mutated Ras-derived peptides. PMID: 9021406 Ref: Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection. PMID: 9307281 |
Ref: Review article: Immunological determinants that may affect the Helicobacter pylori cancer risk. PMID: 9701006 |
Ref: Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. PMID: 10656672 |
Ref: Preventive and therapeutic vaccines against Helicobacter pylori: current status and future challenges. PMID: 10974152 Ref: Diminished Th1-type cytokine production in gastric mucosa T-lymphocytes after H. pylori eradication in duodenal ulcer patients. PMID: 11005624 Ref: Diminished Th1-type cytokine production in gastric mucosa T lymphocytes after H. pylori eradication in duodenal ulcer patients. PMID: 28008493 |
Ref: Shift of the gastric T-cell response in gastric carcinoma. PMID: 11207893 Ref: Search for immunomodulatory effects of blood transfusion in gastric cancer patients: flow cytometry of Th1/Th2 cells in peripheral blood. PMID: 11337907 Ref: T-cell-mediated mucosal immunity in the absence of antibody: lessons from Helicobacter pylori infection. PMID: 11570524 |
Ref: Germ-line p53-targeted disruption inhibits helicobacter-induced premalignant lesions and invasive gastric carcinoma through down-regulation of Th1 proinflammatory responses. PMID: 11830522 Ref: [Local cytokines profile in gastric cancer lesions]. PMID: 11977627 Ref: PSK, a protein-bound polysaccharide, overcomes defective maturation of dendritic cells exposed to tumor-derived factors in vitro. PMID: 12011998 Ref: Efficacy of intraperitoneal thermochemotherapy and immunotherapy in intraperitoneal recurrence after gastrointestinal cancer resection. PMID: 12439917 |
Ref: Helicobacter pylori-associated gastric cancer in INS-GAS mice is gender specific. PMID: 12615707 Ref: Streptococcal preparation OK432 promotes functional maturation of human monocyte-derived dendritic cells. PMID: 12669245 Ref: Effect of total secondary carotenoids extracts from Chlorococcum sp on Helicobacter pylori-infected BALB/c mice. PMID: 12810355 Ref: Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma. PMID: 12814773 Ref: T lymphocyte subsets and Th1/Th2 balance after laparoscopy-assisted distal gastrectomy. PMID: 12820059 Ref: [Helicobacter pylori, gastric inflammation and its consequences]. PMID: 12843963 Ref: [Tuberculosis in compromised hosts]. PMID: 14672050 Ref: [A case of advanced gastric cancer with multiple liver metastases responding completely to hepatic arterial infusion and systemic chemotherapies]. PMID: 14712772 |
Ref: Gastric mucosal cytokine and epithelial cell responses to Helicobacter pylori infection in Mongolian gerbils. PMID: 14743502 Ref: Th1-mediated pathology in mouse models of human disease is ameliorated by concurrent Th2 responses to parasite antigens. PMID: 14965304 Ref: Locoregional immunotherapy of malignant ascites from gastric cancer using DTH-oriented doses of the streptococcal preparation OK-432: Treatment of Th1 dysfunction in the ascites microenvironment. PMID: 15010836 Ref: Helicobacter pylori infection negatively influences pregnancy outcome in a mouse model. PMID: 15068417 Ref: Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta). PMID: 15210820 Ref: Usefulness of immunomodulators for maturation of dendritic cells. PMID: 15254744 Ref: [The repetitive immune cell transfer therapy combining non-myelosuppressive chemotherapy for patients with advanced and refractory cancer]. PMID: 15553672 Ref: [Influence of chemotherapy on Th1/Th2 cytokine switching in stomach cancer patients]. PMID: 15733391 |
Ref: Interferon gamma induction of gastric mucous neck cell hypertrophy. PMID: 15765119 Ref: Helicobacter pylori, T cells and cytokines: the "dangerous liaisons". PMID: 15866204 Ref: [Clinical evaluation of intrapleural or peritoneal repetitive administration of Lentinan and OK-432 for malignant effusion]. PMID: 16315870 Ref: Helicobacter pylori but not high salt induces gastric intraepithelial neoplasia in B6129 mice. PMID: 16322215 |
Ref: Exploitation of interleukin-18 by gastric cancers for their growth and evasion of host immunity. PMID: 16049975 Ref: [Immunotherapeutic efficacy of both helper T lymphocytes and cytotoxic T lymphocytes epitopes augmented dendritic cells tumor vaccine on gastric cancer]. PMID: 16555158 Ref: Helicobacter pylori lipopolysaccharide promotes a Th1 type immune response in immunized mice. PMID: 16621176 Ref: Peptidome from renal cell carcinoma contains antigens recognized by CD4+ T cells and shared among tumors of different histology. PMID: 16914584 Ref: Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse. PMID: 16961812 |
Ref: Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer. PMID: 16885196 Ref: Relationship between Helicobacter pylori virulence factors and regulatory cytokines as predictors of clinical outcome. PMID: 17336120 Ref: VacA and HP-NAP, Ying and Yang of Helicobacter pylori-associated gastric inflammation. PMID: 17368441 Ref: Helicobacter pylori polyclonally activates murine CD4(+) T cells in the absence of antigen-presenting cells. PMID: 17549800 Ref: CagA+ H pylori infection is associated with polarization of T helper cell immune responses in gastric carcinogenesis. PMID: 17589941 |
Ref: Vitamin C supplementation does not protect L-gulono-gamma-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy. PMID: 17990318 Ref: Effect of Helicobacter pylori eradication on gastric carcinogenesis. PMID: 18180700 Ref: Interleukin-13 mucosal production in Helicobacter pylori-related gastric diseases. PMID: 18243827 Ref: Cytokine response following transthoracic and transhiatal esophagectomy in patients with esophageal cancer. PMID: 18632423 Ref: Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population. PMID: 18687755 Ref: Helicobacter pylori immunology and vaccines. PMID: 18783517 Ref: Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells. PMID: 18946358 Ref: [Pre- and post-chemotherapy expressions of Th1 and Th2 type cytokines and their clinical significance in gastric cancer patients]. PMID: 19173830 |
Ref: Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population. PMID: 19058298 Ref: Characterization of tumor antigen peptide-specific T cells isolated from the neoplastic tissue of patients with gastric adenocarcinoma. PMID: 19319530 Ref: Advanced stomach and pancreas cancer successfully treated with combination chemotherapy with S-1/paclitaxel/lentinan. PMID: 19453038 Ref: Helicobacter pylori induces gastric mucosal intestinal metaplasia through the inhibition of interleukin-4-mediated HMG box protein Sox2 expression. PMID: 19520737 Ref: T-bet knockout prevents Helicobacter felis-induced gastric cancer. PMID: 19535625 Ref: Evaluation of a new tumor necrosis factor-alpha-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen. PMID: 19751439 Ref: [Three patients successfully treated with orthopedic surgery for spinal paralysis due to spine metastasis of gastric cancer]. PMID: 20037416 |
Ref: Molecular detection of host cytokine expression in Helicobacter pylori infected patients via semi-quantitative RT-PCR. PMID: 20061762 Ref: The mutations of Th1 cell-specific T-box transcription factor may be associated with a predominant Th2 phenotype in gastric cancers. PMID: 20193034 Ref: PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients. PMID: 20229169 Ref: Construction and characterization of a novel fusion protein MG7-scFv/SEB against gastric cancer. PMID: 20339532 Ref: Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer. PMID: 20550524 Ref: Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer. PMID: 20811886 Ref: Evaluations of interferon-gamma/interleukin-4 ratio and neutrophil/lymphocyte ratio as prognostic indicators in gastric cancer patients. PMID: 20872813 Ref: Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine-induced protection against Helicobacter pylori in mice. PMID: 21038469 Ref: From gastric inflammation to gastric cancer. PMID: 21088411 Ref: NOD1-Mediated Mucosal Host Defense against Helicobacter pylori. PMID: 21152124 |
Ref: Immunogenicity of attenuated measles virus engineered to express Helicobacter pylori neutrophil-activating protein. PMID: 21182995 Ref: Tumor-infiltrating CD4+ Th17 cells produce IL-17 in tumor microenvironment and promote tumor progression in human gastric cancer. PMID: 21369705 Ref: Role of RANTES and its receptor in gastric cancer metastasis. PMID: 21671175 Ref: Environmental and lifestyle influences on disorders of the large and small intestine: implications for treatment. PMID: 21734392 Ref: Relationship between cytokine levels and clinical classification of gastric cancer. PMID: 22126569 Ref: Contribution of gut microbiota to colonic and extracolonic cancer development. PMID: 22179211 |
Ref: Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro. PMID: 22245858 Ref: Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1beta and IL-18. PMID: 22403439 Ref: Serologic evidence that ascaris and toxoplasma infections impact inflammatory responses to Helicobacter pylori in Colombians. PMID: 22404440 Ref: IgG subclasses against Helicobacter pylori isolates: an important tool for disease characterization. PMID: 22686508 Ref: [Association of T helper cell 1 cytokines expressions with prognosis of gastric cancer patients]. PMID: 22736136 Ref: Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer. PMID: 22760549 Ref: Immunotherapy for gastric premalignant lesions and cancer. PMID: 22788127 Ref: Prevalence and clinical relevance of Th17 cells in patients with gastric cancer. PMID: 22940035 Ref: Downregulation of Hlx closely related to the decreased expressions of T-bet and Runx3 in patients with gastric cancer may be associated with a pathological event leading to the imbalance of Th1/Th2. PMID: 23243425 |
Ref: A frequent Toll-like receptor 1 gene polymorphism affects NK- and T-cell IFN-gamma production and is associated with Helicobacter pylori-induced gastric disease. PMID: 23067142 Ref: SLC gene-modified dendritic cells mediate T cell-dependent anti-gastric cancer immune responses in vitro. PMID: 23229068 Ref: CCR3, CCR4, CCR5, and CXCR3 expression in peripheral blood CD4+ lymphocytes in gastric cancer patients. PMID: 23977659 Ref: Golgi phosphoprotein 2 down-regulates the Th1 response in human gastric cancer cells by suppressing IL-12A. PMID: 24289573 |
Ref: Is Helicobacter pylori always a "bad guy"? PMID: 24180409 Ref: Role of DC-SIGN in Helicobacter pylori infection of gastrointestinal cells. PMID: 24389227 Ref: Th17 cell expansion in gastric cancer may contribute to cancer development and metastasis. PMID: 24402773 Ref: Anti-tumor and immunomodulatory activity of peptide fraction from the larvae of Musca domestica. PMID: 24690776 Ref: Inflammation-related factors predicting prognosis of gastric cancer. PMID: 24782611 Ref: Cytokines, cytokine gene polymorphisms and Helicobacter pylori infection: friend or foe? PMID: 24833853 Ref: Systems modeling of the role of interleukin-21 in the maintenance of effector CD4+ T cell responses during chronic Helicobacter pylori infection. PMID: 25053783 Ref: Pattern-recognition receptors and gastric cancer. PMID: 25101079 Ref: Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori. PMID: 25108023 Ref: Helicobacter pylori infection in pediatrics. PMID: 25167945 Ref: Downregulation of Runx3 is closely related to the decreased Th1-associated factors in patients with gastric carcinoma. PMID: 25270738 |
Ref: An integrative approach identified genes associated with drug response in gastric cancer. PMID: 25742747 Ref: Protection against Helicobacter pylori infection in BALB/c mice by oral administration of multi-epitope vaccine of CTB-UreI-UreB. PMID: 25846576 Ref: Significant Association of Interleukin4 Intron 3 VNTR Polymorphism with Susceptibility to Gastric Cancer in a South Indian Population from Telangana. PMID: 26383107 Ref: Immunodominant epitope-specific Th1 but not Th17 responses mediate protection against Helicobacter pylori infection following UreB vaccination of BALB/c mice. PMID: 26434384 Ref: Immunological adjuvant effect of the peptide fraction from the larvae of Musca domestica. PMID: 26630909 |
Ref: Lnc-SGK1 induced by Helicobacter pylori infection and highsalt diet promote Th2 and Th17 differentiation in human gastric cancer by SGK1/Jun B signaling. PMID: 26942879 Ref: Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression. PMID: 26974160 Ref: Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients. PMID: 27057426 Ref: Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis. PMID: 27259856 Ref: Genetically engineered Newcastle disease virus expressing human interferon-lambda1 induces apoptosis in gastric adenocarcinoma cells and modulates the Th1/Th2 immune response. PMID: 27430534 Ref: EGFR regulates macrophage activation and function in bacterial infection. PMID: 27482886 Ref: Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and Prevention. PMID: 27766079 |
Ref: Designing an efficient multi-epitope oral vaccine against Helicobacter pylori using immunoinformatics and structural vaccinology approaches. PMID: 28194462 Ref: Immunochemotherapy benefits in gastric cancer patients stratified by programmed death-1 ligand-1. PMID: 28501128 Ref: Proinflammatory follicular helper T cells promote immunoglobulin G secretion, suppress regulatory B cell development, and correlate with worse clinical outcomes in gastric cancer. PMID: 28631561 Ref: Upregulation of bacterial-specific Th1 and Th17 responses that are enriched in CXCR5(+)CD4(+) T cells in non-small cell lung cancer. PMID: 28982050 |
Ref: Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines. PMID: 29374027 Ref: T cell subsets play an important role in the determination of the clinical outcome of Helicobacter pylori infection. PMID: 29407232 Ref: Antitumor effects and persistence of a novel HER2 CAR T cells directed to gastric cancer in preclinical models. PMID: 29416924 Ref: Immunodominant antigens that induce Th1 and Th17 responses protect mice against Helicobacter pylori infection. PMID: 29552292 Ref: New insights into the inflamed tumor immune microenvironment of gastric cancer with lymphoid stroma: from morphology and digital analysis to gene expression. PMID: 29779068 Ref: The role of T helper 1-cell response in Helicobacter pylori-infection. PMID: 29936093 |