Primary Site >> Colorectal Cancer
Gene >> NEDD4
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Ref: Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas. PMID: 19024597 |
Ref: NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway. PMID: 22974840 Ref: NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling. PMID: 24312311 |
Ref: p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN. PMID: 24141722 |
Ref: Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy. PMID: 25809873 |
Ref: Intestinal knockout of Nedd4 enhances growth of Apc(min) tumors. PMID: 27086928 |
Ref: MCPIP3 as a Potential Metastasis Suppressor Gene in Human Colorectal Cancer. PMID: 29751537 |