Primary Site >> Colorectal Cancer
Gene >> NANOG
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Ref: Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene. PMID: 17322106 Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. PMID: 17611704 Ref: Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells. PMID: 17671748 |
Ref: Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells. PMID: 19554373 |
Ref: Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer. PMID: 20026903 Ref: Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties. PMID: 20587145 Ref: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. PMID: 20630067 |
Ref: Hedgehog signaling and the Gli code in stem cells, cancer, and metastases. PMID: 22114144 Ref: CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer. PMID: 22848268 |
Ref: BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells. PMID: 21365650 Ref: OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer. PMID: 21480394 Ref: Differential expression of nanog1 and nanogp8 in colon cancer cells. PMID: 22079639 Ref: Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells. PMID: 22205615 Ref: Nanog: a potential biomarker for liver metastasis of colorectal cancer. PMID: 22562535 Ref: MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. PMID: 22641368 Ref: Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms. PMID: 22851508 Ref: Epithelial cell adhesion molecule regulates tumor initiation and tumorigenesis via activating reprogramming factors and epithelial-mesenchymal transition gene expression in colon cancer. PMID: 22989882 Ref: Nanog signaling in cancer promotes stem-like phenotype and immune evasion. PMID: 23093782 |
Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer. PMID: 23055106 Ref: NANOG modulates stemness in human colorectal cancer. PMID: 23085761 Ref: Differential localization of LGR5 and Nanog in clusters of colon cancer stem cells. PMID: 23098761 Ref: Up-regulation of microRNA-1290 impairs cytokinesis and affects the reprogramming of colon cancer cells. PMID: 23142292 Ref: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers. PMID: 23175153 Ref: A signature for induced pluripotent stem cell-associated genes in colorectal cancer. PMID: 23307247 Ref: Association of gankyrin and stemness factor expression in human colorectal cancer. PMID: 23508981 Ref: Re: (1) "differential localization of LGR5 and Nanog in clusters of colon cancer stem cells" by Amsterdam A, Raanan C, Schreiber L, Freyhan O, Fabrikant Y, Melzer E, Givol D [Acta Histochem. (2012, October 23), pii: S0065-1281(12)00112-2] and (2) "localiz PMID: 23522104 Ref: Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs. PMID: 23736004 Ref: JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells. PMID: 23911788 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. PMID: 24023739 Ref: AP-1 Gene Expression Levels May Be Correlated with Changes in Gene Expression of Some Stemness Factors in Colon Carcinomas. PMID: 24396595 |
Ref: Prognostic value of stem cell quantification in stage II colon cancer. PMID: 24586330 Ref: Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA. PMID: 24626093 Ref: IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. PMID: 24816405 Ref: ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer. PMID: 24838609 Ref: Characterization of side population cells isolated from the colon cancer cell line SW480. PMID: 24926880 Ref: beta1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells. PMID: 25003232 Ref: Inhibition of NANOG/NANOGP8 downregulates MCL-1 in colorectal cancer cells and enhances the therapeutic efficacy of BH3 mimetics. PMID: 25208882 Ref: Potential role for the Metnase transposase fusion gene in colon cancer through the regulation of key genes. PMID: 25333365 Ref: High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients. PMID: 25500546 |
Ref: Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a. PMID: 24837369 Ref: A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer: Research for Reprogramming of Cancer Cells by MicroRNAs. PMID: 25384704 Ref: Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells. PMID: 25404486 Ref: Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer. PMID: 25497006 Ref: Lithium chloride induces mesenchymaltoepithelial reverting transition in primary colon cancer cell cultures. PMID: 25738332 Ref: Metastatic colon cancer cell populations contain more cancer stem-like cells with a higher susceptibility to natural killer cell-mediated lysis compared with primary colon cancer cells. PMID: 25789015 Ref: Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer. PMID: 26020117 Ref: Simultaneous inhibition of EGFR/VEGFR and cyclooxygenase-2 targets stemness-related pathways in colorectal cancer cells. PMID: 26107817 Ref: Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells. PMID: 26185996 Ref: Verification of ALDH Activity as a Biomarker in Colon Cancer Stem Cells-Derived HT-29 Cell Line. PMID: 26634106 |
Ref: Isolation of colorectal cancer stem-like cells. PMID: 25535115 Ref: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases. PMID: 26031752 Ref: What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue. PMID: 26745821 Ref: MACC1 Induces Tumor Progression in Transgenic Mice and Colorectal Cancer Patients via Increased Pluripotency Markers Nanog and Oct4. PMID: 26758557 Ref: IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer. PMID: 26840943 Ref: Target beta-catenin/CD44/Nanog axis in colon cancer cells by certain N'-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides. PMID: 26944615 Ref: Increased chemoresistance via Snail-Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative. PMID: 26992205 Ref: CCL21 Facilitates Chemoresistance and Cancer Stem Cell-Like Properties of Colorectal Cancer Cells through AKT/GSK-3beta/Snail Signals. PMID: 27057280 Ref: Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer. PMID: 27207017 Ref: Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. PMID: 27225481 Ref: Up-regulation of stem cell markers by P21-activated kinase 1 contributes to 5-fluorouracil resistance of colorectal cancer. PMID: 27260988 Ref: The Effect of Analogues of 1alpha,25-Dihydroxyvitamin D(2) on the Regrowth and Gene Expression of Human Colon Cancer Cells Refractory to 5-Fluorouracil. PMID: 27314328 Ref: IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells. PMID: 27533463 Ref: Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line. PMID: 27746118 Ref: Special AT-rich sequence-binding protein 2 acts as a negative regulator of stemness in colorectal cancer cells. PMID: 27784965 Ref: A comparison of cancer stem cell markers and nonclassical major histocompatibility complex antigens in colorectal tumor and noncancerous tissues. PMID: 27806848 |
Ref: Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice. PMID: 28030837 Ref: Transcriptional repression of miR-200 family members by Nanog in colon cancer cells induces epithelial-mesenchymal transition (EMT). PMID: 28163188 Ref: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer. PMID: 28237538 Ref: IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment. PMID: 28249897 Ref: Chitosan promotes cancer progression and stem cell properties in association with Wnt signaling in colon and hepatocellular carcinoma cells. PMID: 28367998 Ref: Targeting colon cancer stem cells with novel blood cholesterol drug pitavastatin. PMID: 28387909 Ref: Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion. PMID: 28453235 Ref: Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model. PMID: 28545668 Ref: Cholesterol Enhances Colorectal Cancer Progression via ROS Elevation and MAPK Signaling Pathway Activation. PMID: 28618417 Ref: Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. PMID: 28833104 Ref: Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model. PMID: 28881767 Ref: SATB2/beta-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer. PMID: 28887549 Ref: MACC1 facilitates chemoresistance and cancer stem celllike properties of colon cancer cells through the PI3K/AKT signaling pathway. PMID: 28990068 Ref: Clinical significance of Fusobacterium nucleatum, epithelial-mesenchymal transition, and cancer stem cell markers in stage III/IV colorectal cancer patients. PMID: 29081665 Ref: Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer. PMID: 29179207 Ref: Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver. PMID: 29404335 |
Ref: Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features. PMID: 29053388 Ref: Correlation of Cancer Stem-Cell Markers OCT4, SOX2, and NANOG with Clinicopathological Features and Prognosis in Operative Patients with Rectal Cancer. PMID: 29214774 Ref: Ectopic expression of miR-147 inhibits stem cell marker and epithelial-mesenchymal transition (EMT)-related protein expression in colon cancer cells. PMID: 29426374 Ref: High RAC3 expression levels are required for induction and maintaining of cancer cell stemness. PMID: 29464039 Ref: miR-145 Antagonizes SNAI1-Mediated Stemness and Radiation Resistance in Colorectal Cancer. PMID: 29475734 Ref: Pro-metastatic signaling of the trans fatty acid elaidic acid is associated with lipid rafts. PMID: 29556289 Ref: Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells. PMID: 29568348 Ref: Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression. PMID: 29627822 Ref: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer. PMID: 29627827 Ref: Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture. PMID: 29642386 Ref: [LincRNA-ROR functions as a ceRNA to regulate Oct4, Sox2, and Nanog expression by sponging miR-145 and its effect on biologic characteristics of colonic cancer stem cells]. PMID: 29690669 Ref: Protein arginine methyltransferase 8 gene enhances the colon cancer stem cell (CSC) function by upregulating the pluripotency transcription factor. PMID: 29721049 Ref: Ecadherin regulates proliferation of colorectal cancer stem cells through NANOG. PMID: 29845283 Ref: R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells. PMID: 29886802 Ref: Cancer Stemness, Immune Cells, and Epithelial-Mesenchymal Transition Cooperatively Predict Prognosis in Colorectal Carcinoma. PMID: 29921496 Ref: IL-1beta promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem-like properties through PI3K pathway. PMID: 29932233 Ref: The pluripotency network in colorectal cancer pathogenesis and prognosis: an update. PMID: 29944017 Ref: Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis. PMID: 30091203 Ref: Three-Dimensional Ameliorated Biologics Elicit Thymic Renewal in Tumor-Bearing Hosts. PMID: 30150284 Ref: Hypomethylation of NANOG promoter in colonic mucosal cells of obese patients: a possible role of NF-kappaB. PMID: 30157990 Ref: miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. PMID: 30171794 Ref: LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/beta-catenin pathway and predicts poor survival of glioma patients. PMID: 30208924 Ref: Effect of Cinnamic acid and FOLFOX in diminishing side population and downregulating cancer stem cell markers in colon cancer cell line HT-29. PMID: 30209760 Ref: Solasodine reverses stemness and epithelial-mesenchymal transition in human colorectal cancer. PMID: 30268504 Ref: Using of keratin substrate for enrichment of HT29 colorectal cancer stem-like cells. PMID: 30281900 |