Primary Site >> Colorectal Cancer
Gene >> MYB
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Ref: Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma. PMID: 6589609 |
Ref: Mapping of amplified c-myb oncogene, sister chromatid exchanges, and karyotypic analysis of the COLO 205 colon carcinoma cell line. PMID: 3863699 |
Ref: Activated N-ras in a human rectal carcinoma cell line associated with clonal homozygosity in myb locus-restriction fragment polymorphism. PMID: 3017909 |
Ref: Protooncogene abnormalities in colon cancers and adenomatous polyps. PMID: 3557013 Ref: Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa. PMID: 3652034 |
Ref: Oncogene expression in adenocarcinomas of the colon and in colon tumor-derived cell lines. PMID: 3282475 Ref: Biological characterization and oncogene expression in human colorectal carcinoma cell lines. PMID: 3338874 |
Ref: Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells. PMID: 2498320 |
Ref: Proto-oncogene allelic variations in human squamous cell carcinomas of the larynx. PMID: 1679639 Ref: Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb. PMID: 2032228 |
Ref: A study of chromosome 6 allele loss in human colorectal carcinomas. PMID: 1332582 Ref: Pattern of growth factor, proto-oncogene and carcinoembryonic antigen gene expression in human colorectal carcinoma cell lines. PMID: 1495747 |
Ref: Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease. PMID: 8674385 Ref: Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo. PMID: 8695353 Ref: Colonic expression of c-myb is initiated in utero and continues throughout adult life. PMID: 8809414 |
Ref: Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines. PMID: 9135073 Ref: An alternative pathway for expression of p56lck from type I promoter transcripts in colon carcinoma. PMID: 9416836 |
Ref: c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression. PMID: 9823328 |
Ref: DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? PMID: 10343605 |
Ref: Cyclooxygenase-2, a colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB. PMID: 10766162 |
Ref: c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings. PMID: 11290547 Ref: Use of c-myb antisense oligonucleotides to increase the sensitivity of human colon cancer cells to cisplatin. PMID: 11410788 Ref: Transcriptional regulation of the vitamin D(3) receptor gene by ZEB. PMID: 11432806 Ref: Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression. PMID: 11848471 |
Ref: Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. PMID: 11927614 |
Ref: Germline hMLH1 promoter mutation in a Newfoundland HNPCC kindred. PMID: 12919137 Ref: Transcriptional regulation of cyclo-oxygenase expression: three pillars of control. PMID: 14552705 Ref: Antisense oligodeoxynucleotide directed against c-myb has anticancer activity and potentiates the antiproliferative effect of conventional anticancer drugs acting by different mechanisms in human colorectal cancer cells. PMID: 15001837 |
Ref: C-MYB, serum P-53M, genetic instability, labeling index and endoscopic findings in patients with adenoma or colorectal cancer. PMID: 15595638 |
Ref: Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS. PMID: 15684716 Ref: Expression of stress response protein glucose regulated protein-78 mediated by c-Myb. PMID: 15778089 Ref: Effect of the farnesyl transferase inhibitor L-744,832 on the colon cancer cell line DLD-1 and its combined use with radiation and 5-FU. PMID: 16224182 |
Ref: Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers. PMID: 16977606 |
Ref: Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genes. PMID: 17504984 Ref: Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. PMID: 17690249 |
Ref: p38MAPK delta controls c-Myb degradation in response to stress. PMID: 18006338 Ref: Induction of T cell-mediated immunity using a c-Myb DNA vaccine in a mouse model of colon cancer. PMID: 18386000 Ref: Acetylcholinesterase supports anchorage independence in colon cancer. PMID: 18612832 |
Ref: Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. PMID: 20027603 Ref: Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. PMID: 20096072 Ref: Estrogen prevents sustained COLO-205 human colon cancer cell growth by inducing apoptosis, decreasing c-myb protein, and decreasing transcription of the anti-apoptotic protein bcl-2. PMID: 20237898 Ref: Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin. PMID: 20622260 |
Ref: Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells. PMID: 21406062 Ref: MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. PMID: 21455217 Ref: Myb controls intestinal stem cell genes and self-renewal. PMID: 21997934 |
Ref: Inhibition of Myb-dependent gene expression by the sesquiterpene lactone mexicanin-I. PMID: 21986841 Ref: Colorectal cancer mouse models: integrating inflammation and the stroma. PMID: 22188027 |
Ref: Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships. PMID: 23501116 Ref: The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis. PMID: 23618903 Ref: Molecular predictors of sensitivity to the insulin-like growth factor 1 receptor inhibitor Figitumumab (CP-751,871). PMID: 24107449 |
Ref: A comprehensive look at transcription factor gene expression changes in colorectal adenomas. PMID: 24472434 Ref: Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction. PMID: 24535227 Ref: miR-150 functions as a tumour suppressor in human colorectal cancer by targeting c-Myb. PMID: 25230975 Ref: Situational awareness: regulation of the myb transcription factor in differentiation, the cell cycle and oncogenesis. PMID: 25279451 Ref: Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis. PMID: 25290188 |
Ref: Therapeutic DNA vaccination against colorectal cancer by targeting the MYB oncoprotein. PMID: 25671128 Ref: Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis. PMID: 25934694 |
Ref: Intestinal-specific activatable Myb initiates colon tumorigenesis in mice. PMID: 26300002 Ref: Overexpression of c-Myb is associated with suppression of distant metastases in colorectal carcinoma. PMID: 26873484 Ref: High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2. PMID: 26934556 Ref: c-Myb regulates NOX1/p38 to control survival of colorectal carcinoma cells. PMID: 27107996 Ref: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing. PMID: 27504909 Ref: Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer. PMID: 27622014 |
Ref: miR-15a-5p, A Novel Prognostic Biomarker, Predicting Recurrent Colorectal Adenocarcinoma. PMID: 28405803 |
Ref: CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7. PMID: 29549306 Ref: Reassessing the Potential of Myb-targeted Anti-cancer Therapy. PMID: 29675107 Ref: MiR-150 suppresses tumor growth in melanoma through downregulation of MYB. PMID: 29690954 |