Primary Site >> Stomach Cancer

Gene >> MUTYH

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Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion.
PMID: 14518068
Ref: A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.
PMID: 15180946
Ref: Genetic alterations of the MYH gene in gastric cancer.
PMID: 15273732
Ref: MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype.
PMID: 16557584
Ref: Germline mutations and polymorphic variants in MMR, E-cadherin and MYH genes associated with familial gastric cancer in Jiangsu of China.
PMID: 16929514
Ref: OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa.
PMID: 18776649
Ref: A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese.
PMID: 18811933
Ref: Biallelic MYH germline mutations as cause of Muir-Torre syndrome.
PMID: 19998059
Ref: Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.
PMID: 21171015
Ref: Lynch syndrome and MYH-associated polyposis: review and testing strategy.
PMID: 21325953
Ref: Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer.
PMID: 21826668
Ref: AluYb8 insertion in the MUTYH gene and risk of early-onset breast and gastric cancers in the Chinese population.
PMID: 22126480
Ref: Cancer risks for the relatives of colorectal cancer cases with a methylated MLH1 promoter region: data from the Colorectal Cancer Family Registry.
PMID: 22144422
Ref: Detection of APC mosaicism by next-generation sequencing in an FAP patient.
PMID: 25716913
Ref: Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo.
PMID: 27105508
Ref: Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.
PMID: 27194394
Ref: Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
PMID: 27476653
Ref: A Clinicopathologic Evaluation of Incidental Fundic Gland Polyps With Dysplasia: Implications for Clinical Management.
PMID: 28462913
Ref: APC and MUTYH Analysis in FAP Patients: A Novel Mutation in APC Gene and Genotype-Phenotype Correlation.
PMID: 29954149