Primary Site >> Pancreatic Cancer
Gene >> MUC5AC
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Ref: Correlative studies on antigenicity of pancreatic cancer and blood group types. PMID: 3319143 |
Ref: Expression of blood group-related antigens ABH, Lewis A, Lewis B, Lewis X, Lewis Y, and CA 19-9 in pancreatic cancer cells in comparison with the patient's blood group type. PMID: 3166398 |
Ref: [Carbohydrate antigens as a tumor-associated antigen and prognostic indicators in carcinomas of the breast, esophagus, stomach, colorectum, and pancreas]. PMID: 1944163 |
Ref: In situ hybridization shows distinct patterns of mucin gene expression in normal, benign, and malignant pancreas tissues. PMID: 7657125 |
Ref: Expression of MUC apomucins in normal pancreas and pancreatic tumours. PMID: 8976874 |
Ref: Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor. PMID: 10227724 |
Ref: Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. PMID: 11751498 |
Ref: The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas. PMID: 11914624 Ref: Secretion of MUC5AC mucin from pancreatic cancer cells in response to forskolin and VIP. PMID: 12056823 Ref: Biliary papillary neoplasm of the liver. PMID: 12168796 Ref: Cytokeratins 7 and 20, Dpc4, and MUC5AC in the distinction of metastatic mucinous carcinomas in the ovary from primary ovarian mucinous tumors: Dpc4 assists in identifying metastatic pancreatic carcinomas. PMID: 12352188 Ref: Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas. PMID: 12360467 |
Ref: Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells. PMID: 12527922 Ref: A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform. PMID: 12692724 Ref: Expression of mucins and cytokeratins in primary carcinomas of the digestive system. PMID: 12748245 Ref: Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach. PMID: 12833151 Ref: Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray. PMID: 13679454 Ref: Expression of MUC5AC and MUC6 in invasive ductal carcinoma of the pancreas and relationship with prognosis. PMID: 15235131 |
Ref: Expression and localization of MUC1, MUC2, MUC5AC and small intestinal mucin antigen in pancreatic tumors. PMID: 14654947 Ref: Aberrant expression of CDX2 is closely related to the intestinal metaplasia and MUC2 expression in intraductal papillary neoplasm of the liver in hepatolithiasis. PMID: 15048136 |
Ref: Intraductal tubular neoplasms of the pancreas: histogenesis and differentiation. PMID: 15714133 Ref: Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: application of CDX2, CK17, MUC1, and MUC2. PMID: 15725805 Ref: Pancreatic ductal adenocarcinomas with cystic features: neither rare nor uniform. PMID: 15920540 |
Ref: Quantitative analysis of MUC1 and MUC5AC mRNA in pancreatic juice for preoperative diagnosis of pancreatic cancer. PMID: 16052519 Ref: Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intr PMID: 16552336 Ref: Diagnostic utility of mucin profile in fine-needle aspiration specimens of the pancreas: an immunohistochemical study with surgical pathology correlation. PMID: 16628655 Ref: [Diagnosis and differential diagnosis of intraductal papillary mucinous neoplasm of pancreas]. PMID: 16630480 Ref: MUC5AC mucin gene regulation in pancreatic cancer cells. PMID: 16773182 Ref: Immunohistochemical study of the association between the progression of pancreatic ductal lesions and the expression of MUC1, MUC2, MUC5AC, and E-cadherin. PMID: 16789413 Ref: The expression of MUC4 and MUC5AC is related to the biologic malignancy of intraductal papillary mucinous neoplasms of the pancreas. PMID: 17079945 Ref: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas: its histopathologic difference between 2 major types. PMID: 17122512 Ref: A series of 64 cases of pancreatic cystic neoplasia from an institutional study of China. PMID: 17143961 |
Ref: Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. PMID: 17163399 Ref: Mucin expression profile in pancreatic cancer and the precursor lesions. PMID: 17520199 Ref: [Clinicopathologic analysis of 92 cases of pancreatic cystic neoplasm]. PMID: 17535681 Ref: Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas. PMID: 17708554 Ref: Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN. PMID: 17785207 |
Ref: Does ampullary carcinoma arise from distended glands in the papilla of Vater? PMID: 18392709 Ref: MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer. PMID: 18475301 Ref: [Immunohistochemical study of mucins in chronic pancreatitis and ductal adenocarcinoma of the pancreas]. PMID: 18807519 Ref: Precursor lesions of pancreatic cancer. PMID: 20485640 |
Ref: Pancreatic serous microcystic adenoma with extensive oncocytic change. PMID: 19154264 Ref: Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray. PMID: 19276352 Ref: The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays. PMID: 19377061 Ref: Serum and bile biomarkers for cholangiocarcinoma. PMID: 19396965 Ref: Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. PMID: 19440145 Ref: MUC2 but not MUC5 expression correlates with prognosis in radically resected pancreatic cancer patients. PMID: 19587537 Ref: Mucin glycosylation is altered by pro-inflammatory signaling in pancreatic-cancer cells. PMID: 19714813 |
Ref: Combination of MUC5ac and WT-1 immunohistochemistry is useful in distinguishing pancreatic ductal carcinoma from ovarian serous carcinoma in effusion cytology. PMID: 19856421 Ref: Glycosylation variants of mucins and CEACAMs as candidate biomarkers for the diagnosis of pancreatic cystic neoplasms. PMID: 20395854 Ref: RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. PMID: 20492722 Ref: Intraductal tubular neoplasm of the common bile duct. PMID: 20594273 Ref: Predictive factors associated with malignancy of intraductal papillary mucinous pancreatic neoplasms. PMID: 21072900 |
Ref: Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. PMID: 20717734 Ref: GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin. PMID: 20972463 Ref: Invasive ductal carcinoma of the pancreas tail with noninvasive growth through the nondilated main pancreatic duct and macroscopically cystic invasive carcinomatous glands. PMID: 21106422 Ref: Development of a serum biomarker assay that differentiates tumor-associated MUC5AC (NPC-1C ANTIGEN) from normal MUC5AC. PMID: 21197415 Ref: Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer. PMID: 21249315 Ref: Carbohydrate markers of pancreatic cancer. PMID: 21265800 Ref: Similarities and differences between intraductal papillary tumors of the bile duct with and without macroscopically visible mucin secretion. PMID: 21412069 Ref: Identification of HLA-A*0201- and A*2402-restricted epitopes of mucin 5AC expressed in advanced pancreatic cancer. PMID: 21697763 Ref: Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers. PMID: 22220206 |
Ref: The use of specific monoclonal antibodies to target immunogenic tumor membrane proteins in patients with recurrent pancreatic and colon cancer. PMID: 22283657 Ref: Trefoil factor family peptides in normal and diseased human pancreas. PMID: 22286382 Ref: Mucin-based targeted pancreatic cancer therapy. PMID: 22372499 Ref: Genetic markers of malignant transformation in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysis. PMID: 22750975 Ref: Diagnostic challenge: intraductal neoplasms of the pancreatobiliary system. PMID: 23057996 Ref: Intraductal tubular neoplasms of the bile ducts. PMID: 23073323 Ref: Duodenal carcinoma from a duodenal diverticulum mimicking pancreatic carcinoma. PMID: 23093061 Ref: Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy. PMID: 23102107 |
Ref: MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways. PMID: 23292004 Ref: Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms. PMID: 23403822 Ref: Risk factors for pancreatic ductal adenocarcinoma specifically stimulate pancreatic duct glands in mice. PMID: 23438477 Ref: Pathohistological subtype predicts survival in patients with intraductal papillary mucinous neoplasm (IPMN) of the pancreas. PMID: 23532107 Ref: Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype. PMID: 23532108 Ref: Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models. PMID: 23591984 Ref: [Intraductal tubulopapillary neoplasm of the pancreas: a clinicopathologic study of 6 cases]. PMID: 23928532 |
Ref: Is intraductal tubulopapillary neoplasia a new entity in the spectrum of familial pancreatic cancer syndrome? PMID: 24317685 Ref: Intraductal tubulopapillary neoplasm with expansile invasive carcinoma of the pancreas diagnosed by endoscopic ultrasonography-guided fine needle aspiration: a case report. PMID: 24339429 Ref: Case report: Intraductal tubulopapillary neoplasm of the pancreas with unique clear cell phenotype. PMID: 24443801 Ref: Quantitative glycoproteomics analysis reveals changes in N-glycosylation level associated with pancreatic ductal adenocarcinoma. PMID: 24471499 Ref: Novel agents for the treatment of pancreatic cancer. PMID: 24618430 |
Ref: Usefulness of KL-6 in the subtyping of intraductal papillary mucinous neoplasia of the pancreas, including carcinoma, dysplasia, and hyperplasia. PMID: 24908068 Ref: Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: a promising biomarker and therapeutic target for pancreatic cancer. PMID: 25595893 Ref: [The Laparoscopic Enucleation for Branch Duct Type Intraductal Papillary Mucinous Neoplasms Located at the Body of Pancreas: A Case Report]. PMID: 26259409 Ref: A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm? PMID: 26586167 |
Ref: Intraductal tubulopapillary neoplasm of the bile duct: A case report and review of the published work. PMID: 26459784 Ref: [Intraductal papillary mucinous neoplasm of pancreas: analysis of the clinicopathologic features and prognosis]. PMID: 26956959 Ref: Clinicopathological features and surgical outcomes of intraductal tubulopapillary neoplasm of the pancreas: a systematic review. PMID: 27001682 Ref: Semiquantitative immunohistochemistry for mucin (MUC1, MUC2, MUC3, MUC4, MUC5AC, and MUC6) profiling of pancreatic ductal cell adenocarcinoma improves diagnostic and prognostic performance. PMID: 27165582 Ref: A phase 1 dose-escalation study of NEO-102 in patients with refractory colon and pancreatic cancer. PMID: 27449137 Ref: Distinct pathways of pathogenesis of intraductal oncocytic papillary neoplasms and intraductal papillary mucinous neoplasms of the pancreas. PMID: 27591765 Ref: Mucins in neoplasms of pancreas, ampulla of Vater and biliary system. PMID: 27795812 |
Ref: Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinomas. PMID: 27739441 Ref: A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. PMID: 27845339 Ref: Gastric gland mucin-specific O-glycan expression decreases with tumor progression from precursor lesions to pancreatic cancer. PMID: 28685935 Ref: Pancreatic intraductal tubulopapillary neoplasm with associated invasive cancer successfully treated by total pancreatectomy: A case report. PMID: 28693147 Ref: Intraductal tubulopapillary neoplasm (ITPN) of the pancreas associated with an invasive component: a case report with review of the literature. PMID: 29145864 Ref: A Rare Case of Intraductal Tubulopapillary Neoplasm of the Pancreas Rupturing and Causing Acute Peritonitis. PMID: 29282388 |
Ref: Highly Accurate Identification of Cystic Precursor Lesions of Pancreatic Cancer Through Targeted Mass Spectrometry: A Phase IIc Diagnostic Study. PMID: 29166170 Ref: Analysis of sialyl-Lewis x on MUC5AC and MUC1 mucins in pancreatic cancer tissues. PMID: 29408556 Ref: Detection and proteomic characterization of extracellular vesicles in human pancreatic juice. PMID: 29550476 Ref: [A Case of Intraductal Pancreatic Mallignant Tumor with Difficulty in Differentiating between IPMN and ITPN]. PMID: 29650940 Ref: Gastric gland mucin-specific O-glycan expression decreases as tumor cells progress from lobular endocervical gland hyperplasia to cervical mucinous carcinoma, gastric type. PMID: 29845361 Ref: Intrapancreatic recurrence of intraductal tubulopapillary neoplasm (ITPN) 16 years after the initial surgery for noninvasive ITPN: a case report. PMID: 30116990 Ref: Rationale and feasibility of mucin expression profiling by qRT-PCR as diagnostic biomarkers in cytology specimens of pancreatic cancer. PMID: 30268674 Ref: EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma. PMID: 30349952 |