Primary Site >> Colorectal Cancer
Gene >> MUC2
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Ref: Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. PMID: 2703501 |
Ref: Production of MUC1 and MUC2 mucins by human tumor cell lines. PMID: 1713449 Ref: MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism. PMID: 1885763 Ref: The structure of human intestinal apomucins. PMID: 1892319 Ref: Differential mucin gene expression in human pancreatic and colon cancer cells. PMID: 2064602 |
Ref: Expression of MUC1 and MUC2 mucins by human tumor cell lines. PMID: 1283926 Ref: Mucin gene expression in colonic tissues and cell lines. PMID: 1394223 Ref: [Histological localization of mucin core polypeptide MUC-2 in application to the differential diagnosis of adenocarcinoma]. PMID: 1477935 Ref: Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer. PMID: 1569603 Ref: Mucin synthesis and secretion in relation to spontaneous differentiation of colon cancer cells in vitro. PMID: 1728605 |
Ref: Detection of the MUC2 apomucin tandem repeat with a mouse monoclonal antibody. PMID: 7678241 Ref: Heterogeneity of mucin gene expression in normal and neoplastic tissues. PMID: 7678777 Ref: Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells. PMID: 7686147 Ref: cis-Golgi resident proteins and O-glycans are abnormally compartmentalized in the RER of colon cancer cells. PMID: 7691849 Ref: Monoclonal antibodies reacting with the MUC2 mucin core protein. PMID: 8512804 |
Ref: Differential apomucin expression in normal and neoplastic human gastrointestinal tissues. PMID: 8020658 Ref: Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. PMID: 8020672 Ref: Biosynthesis of two distinct types of mucin in HM3 human colon cancer cells. PMID: 8110187 |
Ref: Distribution of sialosyl Tn and Tn antigens within normal and malignant colorectal epithelium. PMID: 7636624 Ref: Patterns of expression of lineage-specific markers during the in vitro-induced differentiation of HT29 colon carcinoma cells. PMID: 7669730 Ref: Characterization of the major sialyl-Lex-positive mucins present in colon, colon carcinoma, and sera of patients with colorectal cancer. PMID: 7850810 Ref: The human MUC2 mucin apoprotein appears to dimerize before O-glycosylation and shares epitopes with the 'insoluble' mucin of rat small intestine. PMID: 8948445 |
Ref: Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma. PMID: 8536891 Ref: Enhanced sialylation of mucin-associated carbohydrate structures in human colon cancer metastasis. PMID: 8613039 Ref: Bile acid-induced alterations of mucin production in differentiated human colon cancer cell lines. PMID: 8729006 Ref: Expression of MUC2 and MUC3 mRNA in human normal, malignant, and inflammatory intestinal tissues. PMID: 8813081 Ref: Significance of MUC1 and MUC2 mucin expression in colorectal cancer. PMID: 8813954 Ref: Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence. PMID: 8859775 Ref: The transcripts of the apomucin genes MUC2, MUC4, and MUC5AC are large and appear as distinct bands. PMID: 8910010 Ref: Alteration in mucin gene expression and biological properties of HT29 colon cancer cell subpopulations. PMID: 8983291 Ref: Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells. PMID: 9035693 Ref: [Anti-tumor activity and immune responses induced by human cancer-associated mucin core peptide]. PMID: 9387291 |
Ref: Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus. PMID: 9065467 Ref: Correlative histochemical study providing evidence for the dual nature of human colorectal cancer mucin. PMID: 9147071 Ref: MUC1 and MUC2 mucins in flat and polypoid colorectal adenomas. PMID: 9215126 Ref: Low O-acetylation of sialyl-Le(x) contributes to its overexpression in colon carcinoma metastases. PMID: 9219830 Ref: Trefoil peptide expression and secretion is regulated by neuropeptides and acetylcholine. PMID: 9277413 Ref: Mucins secreted by cell lines derived from colorectal mucinous carcinoma and adenocarcinoma. PMID: 9291818 Ref: Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. PMID: 9292708 Ref: MUC2 gene suppression in human colorectal carcinomas and their metastases: in vitro evidence of the modulatory role of DNA methylation. PMID: 9426407 Ref: Expression pattern of gastrointestinal markers in native colorectal epithelium, lesions, and carcinomas. PMID: 21590255 |
Ref: Identification of HLA-A2-restricted epitopes of the tumor-associated antigen MUC2 recognized by human cytotoxic T cells. PMID: 9495235 Ref: Coexpression of MUC1 mucin peptide core and the Thomsen-Friedenreich antigen in colorectal neoplasms. PMID: 9506345 Ref: Glycosylation of the tandem repeat unit of the MUC2 polypeptide leading to the synthesis of the Tn antigen. PMID: 9535776 Ref: Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens. PMID: 9829729 Ref: Expression of mucin genes and carbohydrate epitopes in 19 human colon carcinoma cell lines. PMID: 10100757 Ref: [Increased methylation of promotor region suppresses expression of MUC2 gene in colon carcinoma cells]. PMID: 14518264 |
Ref: Liver colonization by human colon cancer cells is reduced by antisense inhibition of MUC2 mucin synthesis. PMID: 9922317 Ref: Human colon adenocarcinomas express a MUC1-associated novel carbohydrate epitope on core mucin glycans defined by a monoclonal antibody (A10) raised against murine Ehrlich tumor cells. PMID: 10070964 Ref: Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation. PMID: 10220499 Ref: Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene. PMID: 10353603 Ref: Serrated adenoma and colorectal cancer. PMID: 10398112 Ref: Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro. PMID: 10411100 Ref: Clinicopathologic and immunohistochemical study of early colorectal cancer with liver metastases. PMID: 10433008 Ref: Separation of distinct MUC2 mucin glycoforms using two anti-peptide monoclonal antibodies. PMID: 10493965 Ref: Modulation of CD4 cell cytokine production by colon cancer-associated mucin. PMID: 10602890 |
Ref: Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue. PMID: 10672055 Ref: Colonic mucin-carbohydrate components in colorectal tumors and their possible relationship to MUC2, p53 and DCC immunoreactivities. PMID: 10729920 Ref: Order and maximum incorporation of N-acetyl-D-galactosamine into threonine residues of MUC2 core peptide with microsome fraction of human-colon-carcinoma LS174T cells. PMID: 10749684 Ref: Evidence for colorectal cancer micrometastases using reverse transcriptase-polymerase chain reaction analysis of MUC2 in lymph nodes. PMID: 10757125 Ref: Clinical significance of MUC1 and MUC2 mucin and p53 protein expression in colorectal carcinoma. PMID: 10768872 Ref: Biological properties and expression of mucins in 5-fluorouracil resistant HT29 human colon cancer cells. PMID: 10853031 Ref: Differential expression of MUC2 and MUC5AC mucin genes in primary ovarian and metastatic colonic carcinoma. PMID: 10872659 Ref: Preliminary study pointing out a significant alteration in the biochemical composition of MUC2 in colorectal mucinous carcinoma. PMID: 10913513 Ref: Phorbol 12-myristate 13-acetate induces alteration in mucin gene expression and biological properties of colon cancer cells. PMID: 10938388 Ref: Alkali-catalyzed beta-elimination of periodate-oxidized glycans: a novel method of chemical deglycosylation of mucin gene products in paraffin embedded sections. PMID: 11425189 |
Ref: Molecular characterization of colorectal neoplasia in translational research. PMID: 11151060 Ref: The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters. PMID: 11212251 Ref: Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation. PMID: 11368880 Ref: Generation of human anti-MUC3 IgG antibodies after in vitro immunization of naive peripheral blood B-lymphocytes. PMID: 11401025 Ref: Comparative study for histology, proliferative activity, glycoproteins, and p53 protein between old and recent colorectal adenomas in Japan. PMID: 11448534 Ref: N-acetylgalactosamine incorporation into a peptide containing consecutive threonine residues by UDP-N-acetyl-D-galactosaminide:polypeptide N-acetylgalactosaminyltransferases. PMID: 11588158 Ref: Differential expression of the chromosome 11 mucin genes in colorectal cancer. PMID: 11673830 Ref: Altered GalNAc-alpha-2,6-sialylation compartments for mucin-associated sialyl-Tn antigen in colorectal adenoma and adenocarcinoma. PMID: 11724906 |
Ref: Immunoreactivity of Lewis blood group and mucin peptide core antigens: correlations with grade of dysplasia and malignant transformation in the colorectal adenoma-carcinoma sequence. PMID: 11813869 Ref: Coexpression of MUC1 with p53 or MUC2 correlates with lymph node metastasis in colorectal carcinomas. PMID: 11850585 Ref: Colorectal cancer in mice genetically deficient in the mucin Muc2. PMID: 11872843 Ref: Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kappa B. PMID: 12077118 Ref: Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer. PMID: 12198708 Ref: Transcriptional activation of the MUC2 gene by p53. PMID: 12374798 Ref: Short chain fatty acids and colon cancer. PMID: 12468628 Ref: [Expression of mucin MUC1 and MUC2 in colorectal carcinoma and their clinical significance]. PMID: 12526222 Ref: Phenotypic expression of gastrointestinal differentiation markers in colorectal adenocarcinomas with liver metastasis. PMID: 12555994 |
Ref: Expression of mucins (MUC1, MUC2, MUC5AC and MUC6) in mucinous carcinoma of the breast: comparison with invasive ductal carcinoma. PMID: 12493022 Ref: The recombinant C-terminus of the human MUC2 mucin forms dimers in Chinese-hamster ovary cells and heterodimers with full-length MUC2 in LS 174T cells. PMID: 12597771 Ref: mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-alpha through a mitogen-activated protein kinase pathway in human colon cancer cells. PMID: 12848848 Ref: Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation. PMID: 12902981 Ref: Phenotypic alteration in malignant transformation of colonic villous tumours: with special reference to a comparison with tubular tumours. PMID: 14511251 Ref: Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. PMID: 14525978 |
Ref: Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone. PMID: 14634802 Ref: Alternative splicing of the human MUC2 gene. PMID: 14678781 Ref: Mucins and mucin binding proteins in colorectal cancer. PMID: 15000151 Ref: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. PMID: 15014022 Ref: Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate. PMID: 15050369 Ref: Mucin core protein expression by colorectal mucinous carcinomas with or without mucus hyperplasia. PMID: 15069618 Ref: Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas. PMID: 15071739 Ref: Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression. PMID: 15087663 Ref: Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon. PMID: 15198362 Ref: Immunophenotypic differences between intestinal-type and low-grade papillary sinonasal adenocarcinomas: an immunohistochemical study of 22 cases utilizing CDX2 and MUC2. PMID: 15252308 Ref: Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells. PMID: 15342386 Ref: The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells. PMID: 15541382 |
Ref: Partial D-amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide. PMID: 15630090 Ref: TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation. PMID: 15665513 Ref: Bile acids induce MUC2 overexpression in human colon carcinoma cells. PMID: 15754327 Ref: Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice. PMID: 15793302 Ref: Overexpression of CD10 and reduced MUC2 expression correlate with the development and progression of colorectal neoplasms. PMID: 15901128 Ref: Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum. PMID: 16142311 Ref: Establishment and characterization of a human colonic mucinous carcinoma cell line with predominant goblet-cell differentiation from liver metastasis. PMID: 16143030 Ref: CD10 expression in colorectal carcinoma correlates with liver metastasis. PMID: 16175325 Ref: Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation. PMID: 16285957 Ref: [A case of anal fistula cancer probably developing from intraluminal dissemination of rectal cancer]. PMID: 16315938 Ref: A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma. PMID: 16382053 |
Ref: Cytokeratin 7/20 and mucin core protein expression in ulcerative colitis-associated colorectal neoplasms. PMID: 16609910 Ref: Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. PMID: 16645863 Ref: Biomarker selection for detection of occult tumour cells in lymph nodes of colorectal cancer patients using real-time quantitative RT-PCR. PMID: 16755296 Ref: Inverse effects of mucin on survival of matched hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer patients. PMID: 16857798 Ref: Sessile serrated adenomas of the large bowel. Clinicopathologic and immunohistochemical study including comparison with common hyperplastic polyps and adenomas. PMID: 16955561 Ref: HATH1 expression in mucinous cancers of the colorectum and related lesions. PMID: 17000673 |
Ref: Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. PMID: 16816167 Ref: Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. PMID: 17163399 Ref: Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats. PMID: 17200374 Ref: Microsatellite-unstable mucinous colorectal carcinoma occurring in the elderly: comparison with medullary type poorly differentiated adenocarcinoma. PMID: 17316416 Ref: The short chain fatty acid, butyrate, stimulates MUC2 mucin production in the human colon cancer cell line, LS174T. PMID: 17374366 Ref: Signet ring cell differentiation in mucinous colorectal carcinoma. PMID: 17471475 Ref: Solution structure of the all L- and D-amino acid-substituted mucin 2 epitope peptides. PMID: 17509526 Ref: Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. PMID: 17517967 Ref: Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer. PMID: 17534889 Ref: [Expression of type 1 and type 2 mucins in colonic epithelial tumors]. PMID: 17642184 Ref: Mucin expression, p53 overexpression, and peritumoral lymphocytic infiltration of advanced colorectal carcinoma with mucus component: is mucinous carcinoma a distinct histological entity? PMID: 17679024 Ref: CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer. PMID: 17906616 Ref: Dietary modulation of colon cancer risk. PMID: 17951506 Ref: Biochemical and immunohistochemical characterisation of mucins in 8 cases of colonic disease--a pilot study. PMID: 17969773 Ref: [Expression and clinical significance of Mucin and E-cadherin in colorectal tumors]. PMID: 17991319 Ref: Mucins in the colorectal neoplastic spectrum with reference to conventional and serrated adenomas. PMID: 18080919 |
Ref: Aberrant expression of SOX2 upregulates MUC5AC gastric foveolar mucin in mucinous cancers of the colorectum and related lesions. PMID: 18027866 Ref: Fhit, Mlh1, P53 and phenotypic expression in the early stage of colorectal neoplasms. PMID: 18097574 Ref: Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer. PMID: 18275842 Ref: Serrated polyps with "intermediate features" of sessile serrated polyp and microvesicular hyperplastic polyp: a practical approach to the classification of nondysplastic serrated polyps. PMID: 18300810 Ref: Clinicopathological analysis of colorectal cancer liver metastasis and intrahepatic cholangiocarcinoma: are they just apples and oranges? PMID: 18329969 Ref: Flat adenoma-carcinoma sequence with high-malignancy potential as demonstrated by CD10 and beta-catenin expression: a different pathway from the polypoid adenoma-carcinoma sequence. PMID: 18370954 Ref: Mucinous colorectal adenocarcinoma: influence of mucin expression (Muc1, 2 and 5) on clinico-pathological features and prognosis. PMID: 18458918 Ref: Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation. PMID: 18690650 Ref: Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. PMID: 18794118 |
Ref: New time-dependent approach to analyse the prognostic significance of immunohistochemical biomarkers in colon cancer and diffuse large B-cell lymphoma. PMID: 18977805 Ref: Differentiating the undifferentiated: immunohistochemical profile of medullary carcinoma of the colon with an emphasis on intestinal differentiation. PMID: 18992917 Ref: The potential of cytokeratin 20 and mucin 2 mRNA as metastasis markers in regional lymph nodes of colon cancer patients investigated by quantitative RT-PCR. PMID: 19119477 Ref: Expression of a core 3 disialyl-Le(x) hexasaccharide in human colorectal cancers: a potential marker of malignant transformation in colon. PMID: 19152289 Ref: Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells. PMID: 19170965 Ref: Macrophage-derived interleukin-6 up-regulates MUC1, but down-regulates MUC2 expression in the human colon cancer HT-29 cell line. PMID: 19201396 Ref: Quantitative RT-PCR detection of tumor cells in sentinel lymph nodes isolated from colon cancer patients with an ex vivo approach. PMID: 19300229 Ref: The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1. PMID: 19328795 Ref: Probiotic-induced changes in the intestinal epithelium: implications in gastrointestinal disease. PMID: 19760989 |
Ref: The role of Reg IV gene and its encoding product in gastric carcinogenesis. PMID: 19740514 Ref: SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. PMID: 19786015 Ref: CK7, CK20, CDX2 and MUC2 Immunohistochemical staining used to distinguish metastatic colorectal carcinoma involving ovary from primary ovarian mucinous adenocarcinoma. PMID: 19926591 Ref: Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer. PMID: 20122155 Ref: NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. PMID: 20145124 Ref: Ampullary cancer. PMID: 20168227 Ref: REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study. PMID: 20183800 Ref: MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues. PMID: 20198318 Ref: Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway. PMID: 20198339 Ref: Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. PMID: 20459814 Ref: Gene expression profiling of colorectal mucinous adenocarcinomas. PMID: 20485009 Ref: [Hath1 gene transfer inhibits the proliferation of colonic cancer cells in vitro]. PMID: 20501407 Ref: Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. PMID: 20532535 Ref: Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma. PMID: 20731025 Ref: Mucin core protein expression in serrated polyps of the large intestine. PMID: 20803031 Ref: Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model. PMID: 20805871 Ref: Immunohistochemical analysis of colorectal cancer with gastric phenotype: claudin-18 is associated with poor prognosis. PMID: 20846265 Ref: Black raspberries inhibit intestinal tumorigenesis in apc1638+/- and Muc2-/- mouse models of colorectal cancer. PMID: 21045162 |
Ref: Primary pulmonary adenocarcinoma with enteric differentiation resembling metastatic colorectal carcinoma: a report of the second case negative for cytokeratin 7. PMID: 20727680 Ref: Loss of E-cadherin and MUC2 expressions correlated with poor survival in patients with stages II and III colorectal carcinoma. PMID: 20865330 Ref: Seromic profiling of colorectal cancer patients with novel glycopeptide microarray. PMID: 21344374 Ref: Immunodiagnostic potential of mucin (MUC2) and Thomsen-Friedenreich (TF) antigens in Egyptian patients with colorectal cancer. PMID: 21381504 Ref: Caco-2 and LS174T cell lines provide different models for studying mucin expression in colon cancer. PMID: 21470648 Ref: Gamma-secretase inhibitor, a potential target therapy for MUC2-positive colorectal carcinoma. PMID: 21520992 Ref: Filiform serrated adenomatous polyposis arising in a diverted rectum of an inflammatory bowel disease patient. PMID: 21569098 Ref: Suppression of mucin 2 enhances the proliferation and invasion of LS174T human colorectal cancer cells. PMID: 21605079 Ref: Keratin 7 expression in colorectal cancer--freak of nature or significant finding? PMID: 21884201 Ref: Expression of adhesion molecules and mucins in human and rhesus macaque gastrointestinal epithelial cells. PMID: 21938678 Ref: [Advanced poorly differentiated adenocarcinoma of the colon with micropapillary carcinoma components except specific cytokeratin expressions, report of a case]. PMID: 22139489 Ref: [Effect of risk factors in colorectal cancer hepatic metastases]. PMID: 22168019 |
Ref: Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer. PMID: 21618511 Ref: MUC2 protein expression status is useful in assessing the effects of hyperthermic intraperitoneal chemotherapy for peritoneal dissemination of colon cancer. PMID: 22266876 Ref: Chronic anti-inflammatory drug therapy inhibits gel-forming mucin production in a murine xenograft model of human pseudomyxoma peritonei. PMID: 22302271 Ref: Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa. PMID: 22556146 Ref: A case of colonic mucinous adenocarcinoma in 19-year-old male patient. PMID: 22741141 Ref: Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients. PMID: 22752373 Ref: Early colorectal carcinomas: CD10 expression, mucin phenotype and submucosal invasion. PMID: 22924846 Ref: Expression of keratin 20 and its clinicopathological significance in intrahepatic cholangiocarcinoma. PMID: 22970052 Ref: Roles of the gel-forming MUC2 mucin and its O-glycosylation in the protection against colitis and colorectal cancer. PMID: 23037153 Ref: MUC5AC/beta-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors. PMID: 23112547 Ref: Clinicopathological Significance of Mucin 2 Immuno-histochemical Expression in Colorectal Cancer: A Meta-Analysis. PMID: 23358901 Ref: Hath1 inhibits proliferation of colon cancer cells probably through up-regulating expression of Muc2 and p27 and down-regulating expression of cyclin D1. PMID: 23464457 |
Ref: Mathematical model of colitis-associated colon cancer. PMID: 23026764 Ref: Loss of MUC2 expression predicts disease recurrence and poor outcome in colorectal carcinoma. PMID: 23179399 Ref: Coordinate regulation of the gel-forming mucin genes at chromosome 11p15.5. PMID: 23303185 Ref: Characterization of PPAR dual ligand MCC-555 in AOM-induced colorectal tumorigenesis. PMID: 23369238 Ref: Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. PMID: 23370770 Ref: Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms. PMID: 23403822 Ref: Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study. PMID: 23409082 Ref: Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo. PMID: 23418447 Ref: Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. PMID: 23474825 Ref: Mutation spectrum in human colorectal cancers and potential functional relevance. PMID: 23497483 Ref: Transmembrane mucin MUC1 overexpression and its association with CD10(+) myeloid cells, transforming growth factor-beta1 expression, and tumor budding grade in colorectal cancer. PMID: 23566254 Ref: Clinical applications of gene expression in colorectal cancer. PMID: 23730510 Ref: Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype. PMID: 23807779 Ref: The cysteinyl leukotriene 2 receptor contributes to all-trans retinoic acid-induced differentiation of colon cancer cells. PMID: 23829413 Ref: Differential mucin phenotypes and their significance in a variation of colorectal carcinoma. PMID: 23840140 Ref: Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy. PMID: 23874993 Ref: Differentiation- and apoptosis-inducing activities of rice bran extracts in a human colon cancer cell line. PMID: 24425959 Ref: Mucinous differentiation in colorectal cancer: molecular, histological and clinical aspects. PMID: 24494463 |
Ref: The role of KCNQ1 in mouse and human gastrointestinal cancers. PMID: 23975432 Ref: Demethylation effect of the antineoplaston AS2-1 on genes in colon cancer cells. PMID: 24213840 Ref: Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer. PMID: 24288256 Ref: High expression of sLex associated with poor survival in Argentinian colorectal cancer patients. PMID: 24425323 Ref: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma. PMID: 24621249 Ref: Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases. PMID: 24696747 Ref: Intestinal type of lung adenocarcinoma in younger adults. PMID: 24782938 Ref: Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies. PMID: 24840470 Ref: Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice. PMID: 24894865 Ref: MicroRNA profiling in Muc2 knockout mice of colitis-associated cancer model reveals epigenetic alterations during chronic colitis malignant transformation. PMID: 24941171 Ref: Predictors of lymph node metastasis in T1 colorectal carcinoma: an immunophenotypic analysis of 265 patients. PMID: 25003285 Ref: Colocalization of beta-catenin with Notch intracellular domain in colon cancer: a possible role of Notch1 signaling in activation of CyclinD1-mediated cell proliferation. PMID: 25073953 Ref: The effect of glycosylation on the antibody recognition of a MUC2 mucin epitope. PMID: 25093517 Ref: Reversed polarity of the glandular epithelial cells in micropapillary carcinoma of the large intestine and the EMA/MUC1 immunostain. PMID: 25158820 Ref: REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PMID: 25295732 Ref: Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model. PMID: 25322805 Ref: Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma. PMID: 25423035 Ref: A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor. PMID: 25551773 |
Ref: Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling. PMID: 25263446 Ref: MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer. PMID: 25403854 Ref: Bile acid induces MUC2 expression and inhibits tumor invasion in gastric carcinomas. PMID: 25475007 Ref: Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells. PMID: 25701318 Ref: Immunohistochemical study of MUC1, MUC2 and MUC5AC in colorectal carcinoma and review of literature. PMID: 25731647 Ref: Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer. PMID: 25826503 Ref: Induction of duodenal mucosal tumors of intestinal epithelial cell origin showing frequent nuclear beta-catenin accumulation similar to the concurrently induced colorectal tumors in rats after treatment with azoxymethane. PMID: 25899166 Ref: Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation. PMID: 26307678 Ref: Mulberry fruit prevents LPS-induced NF-kappaB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. PMID: 26615818 Ref: The molecular background of mucinous carcinoma beyond MUC2. PMID: 27499889 |
Ref: Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer. PMID: 26364605 Ref: The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential. PMID: 26476272 Ref: Early detection of colonic dysplasia by magnetic resonance molecular imaging with a contrast agent raised against the colon cancer marker MUC5AC. PMID: 26762591 Ref: Dietary flaxseed modulates the colonic microenvironment in healthy C57Bl/6 male mice which may alter susceptibility to gut-associated diseases. PMID: 26878783 Ref: Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer. PMID: 26898938 Ref: High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer. PMID: 27033117 Ref: Mucinous Balls Tangled With Mesothelial Cells and MUC2-Positive Cancer Cells in the Ascites of Pseudomyxoma Peritonei. PMID: 27079739 Ref: The Reduction-insensitive Bonds of the MUC2 Mucin Are Isopeptide Bonds. PMID: 27129250 Ref: Can supplementation of phytoestrogens/insoluble fibers help the management of duodenal polyps in familial adenomatous polyposis? PMID: 27207660 Ref: MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer. PMID: 27271572 Ref: MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance. PMID: 27298226 Ref: Differential expression of mucins in Middle Eastern patients with colorectal cancer. PMID: 27347157 Ref: Structural Change in Microbiota by a Probiotic Cocktail Enhances the Gut Barrier and Reduces Cancer via TLR2 Signaling in a Rat Model of Colon Cancer. PMID: 27384052 Ref: Altered expression of Butyrophilin (BTN) and BTN-like (BTNL) genes in intestinal inflammation and colon cancer. PMID: 27957327 Ref: Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment. PMID: 28119740 |
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