Primary Site >> Colorectal Cancer
Gene >> MUC1
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Ref: Adenocarcinoid tumor of the colon arising in preexisting ulcerative colitis. PMID: 7248910 |
Ref: Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin. PMID: 6193872 Ref: Carcinoma of the colon and rectum in patients less than 40 years of age. PMID: 6623323 Ref: Gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein. PMID: 6883374 |
Ref: Carcinoma in anorectal fistula of rectal mucosal origin. PMID: 6087605 Ref: Immunoreactive secretory component of IgA in human tissues and tumors. PMID: 6391147 |
Ref: A prospective study of dysplasia and carcinoma in the rectal biopsies and rectal stump of eight patients following ileorectal anastomosis in ulcerative colitis. PMID: 4085981 |
Ref: Monoclonal antibodies reacting with colorectal tumours. PMID: 2428281 Ref: The occurrence and clinicopathological significance of serotonin immunoreactive cells in large bowel carcinoma. PMID: 3525789 |
Ref: Comparison of phenotypic and genotypic features in human primary large bowel carcinomas and lymph node metastases. PMID: 3475170 |
Ref: A comparison of carcinoembryonic antigen (CEA) and epithelial membrane antigen (EMA) in human colorectal cancer. PMID: 3209300 Ref: Expression of a high molecular weight mucin-type glycoprotein in human colon cancer as defined by monoclonal antibody 1D3. PMID: 3286482 |
Ref: [Clinical relevance of tumor markers]. PMID: 2672606 Ref: Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer. PMID: 2908846 |
Ref: Epithelial markers in pancreatic carcinoma: immunoperoxidase localisation of DD9, CEA, EMA and CAM 5.2. PMID: 1696288 Ref: The adenoma to carcinoma sequence. PMID: 2163117 Ref: Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients. PMID: 2224793 |
Ref: Production of MUC1 and MUC2 mucins by human tumor cell lines. PMID: 1713449 Ref: Purification and characterization of a membrane-bound and a secreted mucin-type glycoprotein carrying the carcinoma-associated sialyl-Lea epitope on distinct core proteins. PMID: 1718981 Ref: Characterization of mucin antigens recognized by monoclonal antibodies raised against human colon cancer cells. PMID: 1988095 Ref: Differential mucin gene expression in human pancreatic and colon cancer cells. PMID: 2064602 Ref: Intraoperative localization of colorectal cancers using radiolabelled monoclonal antibodies. PMID: 2070229 |
Ref: Expression of MUC1 and MUC2 mucins by human tumor cell lines. PMID: 1283926 Ref: Second generation anti-MUC1 peptide monoclonal antibodies. PMID: 1373108 Ref: Mucin gene expression in colonic tissues and cell lines. PMID: 1394223 Ref: Differences in expression of SPan-1 and CA15-3 antigens in blood and tissues. PMID: 1428228 Ref: Patterns of growth and differentiation in the colon carcinoma cell line LIM 1863. PMID: 1544710 Ref: Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer. PMID: 1569603 Ref: Mucin associated Tn and sialosyl-Tn antigen expression in colorectal polyps. PMID: 1582597 |
Ref: [Preparation and identification of monoclonal antibodies against different epitopes on TAG-72 antigen]. PMID: 7515344 Ref: Heterogeneity of mucin gene expression in normal and neoplastic tissues. PMID: 7678777 Ref: Discrimination of MUC1 mucins from other sialyl-Le(a)-carrying glycoproteins produced by colon carcinoma cells using a novel monoclonal antibody. PMID: 7679050 Ref: 11q deletions in human colorectal carcinomas: cytogenetics and restriction fragment length polymorphism analysis. PMID: 7680221 Ref: Hyperplastic polyps: a cell lineage which both synthesizes and secretes trefoil-peptides and has phenotypic similarity with the ulcer-associated cell lineage. PMID: 7681255 Ref: Altered glycosylation of the MUC-1 protein core contributes to the colon carcinoma-associated increase of mucin-bound sialyl-Lewis(x) expression. PMID: 7689422 Ref: Reactivity of monoclonal antibodies directed against lung cancer antigens with human lung, breast and colon cancer cell lines. PMID: 8082312 Ref: Regulation of sialomucin production in colon carcinoma cells. PMID: 8098036 Ref: Monoclonal antibodies reacting with the MUC2 mucin core protein. PMID: 8512804 |
Ref: Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients. PMID: 7514493 Ref: Adenocarcinoma in the rectum of a capped langur (Presbytis pileata). PMID: 7537336 Ref: Differential apomucin expression in normal and neoplastic human gastrointestinal tissues. PMID: 8020658 Ref: Transcriptional regulation of the MUC1 mucin gene in colon carcinoma cells by a soluble factor. Identification of a regulatory element. PMID: 8195140 Ref: Localization of tumor-reactive lymph node lymphocytes in vivo using radiolabeled monoclonal antibody. PMID: 8299079 Ref: [Molecular biological analyses of mucin core proteins and their clinical application]. PMID: 8311484 Ref: Lack of tissue-specificity of mucin markers in a lung-cancer model - biochemical approach. PMID: 21559722 |
Ref: Immunomagnetic purification of human breast carcinoma cells allows tumor-specific detection of multidrug resistance gene 1-mRNA by reverse transcriptase polymerase chain reaction in fine-needle aspirates. PMID: 7540237 Ref: Distribution of sialosyl Tn and Tn antigens within normal and malignant colorectal epithelium. PMID: 7636624 Ref: Studies on the order and site specificity of GalNAc transfer to MUC1 tandem repeats by UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase from milk or mammary carcinoma cells. PMID: 7744025 Ref: Characterization of the major sialyl-Lex-positive mucins present in colon, colon carcinoma, and sera of patients with colorectal cancer. PMID: 7850810 |
Ref: Effect of MUC1 mucin, an anti-adhesion molecule, on tumor cell growth. PMID: 8641988 Ref: [Growth patterns of colorectal carcinoma and mucin property of transitional mucosa]. PMID: 8642752 Ref: Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumor cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte adhesion to E-selectin-expressing endothelial cells. PMID: 8707893 Ref: Significance of MUC1 and MUC2 mucin expression in colorectal cancer. PMID: 8813954 Ref: Mucin-1-related T cell infiltration in colorectal carcinoma. PMID: 8830738 Ref: Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence. PMID: 8859775 Ref: Specificity analysis of murine monoclonal antibodies reactive with Tn, sialylated Tn, T, and monosialylated (2-->6) T antigens. PMID: 8985750 Ref: Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells. PMID: 9035693 Ref: Antigen heterogeneity in advanced colorectal and breast cancer. PMID: 21541535 |
Ref: A MUC1 mucin secreted from a colon carcinoma cell line inhibits target cell lysis by natural killer cells. PMID: 9073389 Ref: Prognostic significance of preimmunotherapy serum CA27.29 (MUC-1) mucin level after active specific immunotherapy of metastatic adenocarcinoma patients. PMID: 9101416 Ref: Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucins secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion. PMID: 9143414 Ref: Correlative histochemical study providing evidence for the dual nature of human colorectal cancer mucin. PMID: 9147071 Ref: Cytokeratins, CEA, and mucin histochemistry in the diagnosis and characterization of extramammary Paget's disease. PMID: 9208972 Ref: MUC1 and MUC2 mucins in flat and polypoid colorectal adenomas. PMID: 9215126 Ref: Low O-acetylation of sialyl-Le(x) contributes to its overexpression in colon carcinoma metastases. PMID: 9219830 Ref: Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation. PMID: 9246205 Ref: Breast cancer associated mucin: a review. PMID: 9269507 Ref: [Micrometastasis of colorectal carcinoma in bone marrow with immunohistochemical staining]. PMID: 10678046 Ref: Expression pattern of gastrointestinal markers in native colorectal epithelium, lesions, and carcinomas. PMID: 21590255 |
Ref: Immunohistochemical detection of the MUC1 gene product in human cancers grown in scid mice. PMID: 9405502 Ref: A microsatellite within the MUC1 locus at 1q21 is altered in the neoplastic cells of breast cancer patients. PMID: 9406583 Ref: Reactivity of antibodies with highly glycosylated MUC1 mucins from colon carcinoma cells and bile. PMID: 9422097 Ref: Resistance of the human colon carcinoma cell line HCT-8 to methotrexate results in selection of cells with features of enterocytic differentiation. PMID: 9495241 Ref: Coexpression of MUC1 mucin peptide core and the Thomsen-Friedenreich antigen in colorectal neoplasms. PMID: 9506345 Ref: Detection of circulating anti-MUC1 mucin core protein antibodies in patients with colorectal cancer. PMID: 9658314 Ref: Immunoreactive MUC1 expression at the deepest invasive portion correlates with prognosis of colorectal cancer. PMID: 9663420 Ref: Orthotopic xenografts of human melanoma and colonic and ovarian carcinoma in sheep to evaluate radioimmunotherapy. PMID: 9716032 Ref: Purification of nuclear proteins that potentially regulate transcription of the MUC1 mucin gene induced by a soluble factor. PMID: 9722669 Ref: Selection of tumor antigens as targets for immune attack using immunohistochemistry: protein antigens. PMID: 9829729 Ref: Expression of mucin genes and carbohydrate epitopes in 19 human colon carcinoma cell lines. PMID: 10100757 |
Ref: Breast cancer imaging with radiolabeled antibodies. PMID: 9990682 Ref: Human colon adenocarcinomas express a MUC1-associated novel carbohydrate epitope on core mucin glycans defined by a monoclonal antibody (A10) raised against murine Ehrlich tumor cells. PMID: 10070964 Ref: CFTR expression does not influence glycosylation of an epitope-tagged MUC1 mucin in colon carcinoma cell lines. PMID: 10089213 Ref: An atraumatic method to establish human colon carcinoma in long-term culture. PMID: 10090822 Ref: MUC1 expression in intramucosal colorectal neoplasms. Possible involvement in histogenesis and progression. PMID: 10202278 Ref: Follicle-like structures formed by intestinal cell lines derived from the HT29-D4 adenocarcinoma cell line: morphological and functional characterization. PMID: 10399829 Ref: Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro. PMID: 10411100 Ref: Modulation of CD4 cell cytokine production by colon cancer-associated mucin. PMID: 10602890 Ref: [Tumor genesis and prognostic factors in colorectal carcinoma with special consideration of tumor localization]. PMID: 10670092 |
Ref: Clinical significance of MUC1 and E-cadherin expression, cellular proliferation, and angiogenesis at the deepest invasive portion of colorectal cancer. PMID: 10601549 Ref: pS2 expression as a possible diagnostic marker of colorectal carcinoma in ulcerative colitis. PMID: 10671663 Ref: Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue. PMID: 10672055 Ref: Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer. PMID: 10706135 Ref: Molecular detection of blood-borne epithelial cells in colorectal cancer patients and in patients with benign bowel disease. PMID: 10719724 Ref: Thomsen-Friedenreich antigen presents as a prognostic factor in colorectal carcinoma: A clinicopathologic study of 264 patients. PMID: 10738210 Ref: Immunodiscrimination of colorectal neoplasia using MUC1 antibodies: discrepant findings in tissue versus stool. PMID: 10749323 Ref: Increased expression after X-irradiation of MUC1 in cultured human colon carcinoma HT-29 cells. PMID: 10760692 Ref: Clinical significance of MUC1 and MUC2 mucin and p53 protein expression in colorectal carcinoma. PMID: 10768872 Ref: Vital immunostaining of human gastric and colorectal cancers grafted into nude mice: a preclinical assessment of a potential adjunct to videoendoscopy. PMID: 11063218 Ref: T cell responses in colorectal cancer patients: evidence for class II HLA-restricted recognition of shared tumor-associated antigens. PMID: 11093821 Ref: Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer. PMID: 11103784 Ref: Alkali-catalyzed beta-elimination of periodate-oxidized glycans: a novel method of chemical deglycosylation of mucin gene products in paraffin embedded sections. PMID: 11425189 |
Ref: Molecular characterization of colorectal neoplasia in translational research. PMID: 11151060 Ref: CA19-9 epitope a possible marker for MUC-1/Y protein. PMID: 11295060 Ref: Generation of human anti-MUC3 IgG antibodies after in vitro immunization of naive peripheral blood B-lymphocytes. PMID: 11401025 Ref: MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern. PMID: 11562739 Ref: Pretargeting of human mammary carcinoma xenografts with bispecific anti-MUC1/anti-Ga chelate antibodies and immunoscintigraphy with PET. PMID: 11578904 Ref: Sialosyl Le(a)-carrying gangliosides present on the surface of colon carcinoma cells are not directly involved in adhesion to E-selectin. PMID: 11831392 Ref: A rat model to study the role of STn antigen in colon cancer. PMID: 12820721 Ref: Tumor cell MUC1 and CD43 are glycosylated differently with sialyl-Lewis a and x epitopes and show variable interactions with E-selectin under physiological flow conditions. PMID: 12820726 |
Ref: Immunoreactivity of Lewis blood group and mucin peptide core antigens: correlations with grade of dysplasia and malignant transformation in the colorectal adenoma-carcinoma sequence. PMID: 11813869 Ref: Beta-catenin--a linchpin in colorectal carcinogenesis? PMID: 11839557 Ref: Coexpression of MUC1 with p53 or MUC2 correlates with lymph node metastasis in colorectal carcinomas. PMID: 11850585 Ref: Basic studies on a labeled anti-mucin antibody detectable by infrared-fluorescence endoscopy. PMID: 11993509 Ref: A human immunoglobulin G1 antibody originating from an in vitro-selected Fab phage antibody binds avidly to tumor-associated MUC1 and is efficiently internalized. PMID: 12000712 Ref: Current concepts in immunotherapy for the treatment of colorectal cancer. PMID: 12018689 Ref: Antigenic and immunologic characterization of an allogeneic colon carcinoma vaccine. PMID: 12100028 Ref: [Expression of mucin MUC1 and MUC2 in colorectal carcinoma and their clinical significance]. PMID: 12526222 Ref: Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors. PMID: 12530077 Ref: The expression of human FUT1 in HT-29/M3 colon cancer cells instructs the glycosylation of MUC1 and MUC5AC apomucins. PMID: 12652076 Ref: In vivo glycosylation of MUC1 in airway epithelial cells. PMID: 14707484 |
Ref: Expression of mucins (MUC1, MUC2, MUC5AC and MUC6) in mucinous carcinoma of the breast: comparison with invasive ductal carcinoma. PMID: 12493022 Ref: The contribution of tandem repeat number to the O-glycosylation of mucins. PMID: 12626424 Ref: Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells. PMID: 12640674 Ref: Modulation of mucin synthesis by gamma-interferon in human colon adenocarcinoma cells. PMID: 12743441 Ref: Infusion of unpulsed dendritic cells derived from granulocyte/macrophage colony-stimulating factor-mobilized peripheral blood CD34+ cells and monocytes in patients with advanced carcinoma. PMID: 12857369 Ref: Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat. PMID: 14636048 |
Ref: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. PMID: 14998492 Ref: Mucins and mucin binding proteins in colorectal cancer. PMID: 15000151 Ref: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. PMID: 15014022 Ref: MUC1 can interact with adenomatous polyposis coli in breast cancer. PMID: 15020226 Ref: Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate. PMID: 15050369 Ref: Mucin core protein expression by colorectal mucinous carcinomas with or without mucus hyperplasia. PMID: 15069618 Ref: Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas. PMID: 15071739 Ref: MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis. PMID: 15102686 Ref: Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon. PMID: 15198362 Ref: Spread of prostate carcinoma to the perirectal lymph node basin: analysis of 112 rectal resections over a 10-year span for primary rectal adenocarcinoma. PMID: 15316314 Ref: MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. PMID: 15322085 Ref: Expression of the cell surface mucin gene family in adenocarcinomas. PMID: 15375564 Ref: Expression of MUC1 recognized by monoclonal antibody MY.1E12 is a useful biomarker for tumor aggressiveness of advanced colon carcinoma. PMID: 15554388 |
Ref: Induction of antigen-specific CD4- and CD8-mediated T-cell responses by fusions of autologous dendritic cells and metastatic colorectal cancer cells. PMID: 15945098 Ref: Primary invasive micropapillary carcinoma of the colon. PMID: 16241995 Ref: Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells. PMID: 16278414 |
Ref: New MUC1 serum immunoassay differentiates pancreatic cancer from pancreatitis. PMID: 16344318 Ref: N-Glycosylation of the MUC1 mucin in epithelial cells and secretions. PMID: 16585136 Ref: Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. PMID: 16645863 Ref: MUC1 cytoplasmic tail detection using CT33 polyclonal and CT2 monoclonal antibodies in breast and colorectal tissue. PMID: 16691537 Ref: A mucoadhesive in situ gel delivery system for paclitaxel. PMID: 16796370 Ref: Inverse effects of mucin on survival of matched hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer patients. PMID: 16857798 |
Ref: Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. PMID: 16816167 Ref: MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model. PMID: 17166639 Ref: Streptococcal preparation OK-432 promotes fusion efficiency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells. PMID: 17182602 Ref: The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma. PMID: 17195076 Ref: Downregulated P1 promoter-driven hepatocyte nuclear factor-4alpha expression in human colorectal carcinoma is a new prognostic factor against liver metastasis. PMID: 17300672 Ref: In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression. PMID: 17311291 Ref: The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer. PMID: 17349047 Ref: Subcellular localization of KL-6 mucin in colorectal carcinoma cell lines: association with metastatic potential and cell morphology. PMID: 17390044 Ref: Cutting edge: transgenic expression of human MUC1 in IL-10-/- mice accelerates inflammatory bowel disease and progression to colon cancer. PMID: 17617560 Ref: [Expression of type 1 and type 2 mucins in colonic epithelial tumors]. PMID: 17642184 Ref: Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer. PMID: 17657837 Ref: Mucin expression, p53 overexpression, and peritumoral lymphocytic infiltration of advanced colorectal carcinoma with mucus component: is mucinous carcinoma a distinct histological entity? PMID: 17679024 Ref: Clear cell adenocarcinoma of colorectum: a case report and review of the literature. PMID: 17715642 Ref: Biochemical and immunohistochemical characterisation of mucins in 8 cases of colonic disease--a pilot study. PMID: 17969773 Ref: [Expression and clinical significance of Mucin and E-cadherin in colorectal tumors]. PMID: 17991319 Ref: Mucins in the colorectal neoplastic spectrum with reference to conventional and serrated adenomas. PMID: 18080919 |
Ref: MUC1 and colorectal cancer pathophysiology considerations. PMID: 18407586 Ref: Mucinous colorectal adenocarcinoma: influence of mucin expression (Muc1, 2 and 5) on clinico-pathological features and prognosis. PMID: 18458918 Ref: Positive KL-6 mucin expression combined with decreased membranous beta-catenin expression indicates worse prognosis in colorectal carcinoma. PMID: 18949395 Ref: Differential effector mechanisms induced by vaccination with MUC1 DNA in the rejection of colon carcinoma growth at orthotopic sites and metastases. PMID: 19018774 Ref: Lectin-epithelial interactions in the human colon. PMID: 19021580 |
Ref: Differentiating the undifferentiated: immunohistochemical profile of medullary carcinoma of the colon with an emphasis on intestinal differentiation. PMID: 18992917 Ref: Apical membrane localization of glycogen synthase kinase 3beta protein in normal colon epithelium and aberrant distribution in colorectal cancer. PMID: 19022564 Ref: Macrophage-derived interleukin-6 up-regulates MUC1, but down-regulates MUC2 expression in the human colon cancer HT-29 cell line. PMID: 19201396 Ref: Humoral immune response to abnormal MUC1 in subjects with colorectal adenoma and cancer. PMID: 19217667 Ref: Cyclin D1 negatively regulates the expression of differentiation genes in HT-29 M6 mucus-secreting colon cancer cells. PMID: 19303206 Ref: Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. PMID: 19417139 Ref: KL-6 is another useful marker in assessing a micropapillary pattern in carcinomas of the breast and urinary bladder, but not the colon. PMID: 19536620 Ref: Pedunculated polyp of early sigmoid colon cancer with invasive micropapillary carcinoma. PMID: 19561116 Ref: KL-6 mucin in metastatic liver cancer tissues from primary colorectal carcinoma. PMID: 19760920 Ref: Colonic carcinoma with a pancreatic acinar cell differentiation. A case report. PMID: 19908063 |
Ref: Aberrant expression of MUC1 mucin in pediatric inflammatory bowel disease. PMID: 19025220 Ref: Ampullary cancer. PMID: 20168227 Ref: Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer. PMID: 20332301 Ref: MUC1 regulates nuclear localization and function of the epidermal growth factor receptor. PMID: 20406885 Ref: Mucinous adenocarcinoma showing different clinicopathological and molecular characteristics in relation to different colorectal cancer subgroups. PMID: 20532535 Ref: Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases. PMID: 20572035 Ref: Organ microenvironment plays significant roles through Fas ligand in vaccine-induced CD4(+) T cell dependent suppression of tumor growth at the orthotopic site. PMID: 20637014 Ref: Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer. PMID: 20716165 Ref: Neutralization of interleukin (IL)-10 released by monocytes/macrophages enhances the up-regulatory effect of monocyte/macrophage-derived IL-6 on expressions of IL-6 and MUC1, and migration in HT-29 colon cancer cells. PMID: 20851386 |
Ref: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating beta-galactoside:alpha2,3-sialyltransferase 6 gene. PMID: 21168523 Ref: Loss of E-cadherin independently predicts the lymph node status in colorectal cancer. PMID: 21233674 Ref: Clinicopathological and molecular characterization of colorectal micropapillary carcinoma. PMID: 21336262 Ref: Seromic profiling of colorectal cancer patients with novel glycopeptide microarray. PMID: 21344374 Ref: Immunodiagnostic potential of mucin (MUC2) and Thomsen-Friedenreich (TF) antigens in Egyptian patients with colorectal cancer. PMID: 21381504 Ref: Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1, trefoil factor-3, and tumor necrosis factor-alpha in colon of dextran sodium sulfate-treated C57BL/6 mice. PMID: 21593350 Ref: Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer. PMID: 21664646 Ref: Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium. PMID: 21933892 Ref: Expression of adhesion molecules and mucins in human and rhesus macaque gastrointestinal epithelial cells. PMID: 21938678 Ref: [Expression of mucin regulated by recombinant human interleukin-6 in HT-29 cell of colon cancer]. PMID: 22116730 Ref: Enhanced induction of anti-tumor CTLs in vitro by a lentivirus-transduced dendritic cell vaccine expressing secondary lymphoid tissue chemokine and mucin 1. PMID: 22393946 Ref: Natural and Induced Humoral Responses to MUC1. PMID: 24212946 Ref: Primary micropapillary carcinoma of the colon: a case report and literature review. PMID: 26190714 |
Ref: Evaluation of contrast medium enhancement and [(18)F]-FDG uptake of liver metastasis in PET/CT prior to therapy. PMID: 21300504 Ref: Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients. PMID: 21823122 Ref: MUC1 expression in pulmonary metastatic tumors: a comparison of primary lung cancer. PMID: 21964914 Ref: Overexpression of S100B, TM4SF4, and OLFM4 genes is correlated with liver metastasis in Taiwanese colorectal cancer patients. PMID: 22011044 Ref: LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases: a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial. PMID: 22494623 Ref: Prevention of colitis-associated colon cancer using a vaccine to target abnormal expression of the MUC1 tumor antigen. PMID: 22737601 Ref: Early colorectal carcinomas: CD10 expression, mucin phenotype and submucosal invasion. PMID: 22924846 Ref: Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients. PMID: 23146106 Ref: Correlation between auto-antibodies to survivin and MUC1 variable number tandem repeats in colorectal cancer. PMID: 23317217 |
Ref: T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer. PMID: 22729559 Ref: Mathematical model of colitis-associated colon cancer. PMID: 23026764 Ref: MUC1 vaccine for individuals with advanced adenoma of the colon: a cancer immunoprevention feasibility study. PMID: 23248097 Ref: Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo. PMID: 23418447 Ref: Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. PMID: 23474825 Ref: Transmembrane mucin MUC1 overexpression and its association with CD10(+) myeloid cells, transforming growth factor-beta1 expression, and tumor budding grade in colorectal cancer. PMID: 23566254 Ref: Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21). PMID: 23620673 Ref: A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. PMID: 23657083 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 Ref: Downregulation of hematopoietic MUC1 during experimental colitis increases tumor-promoting myeloid-derived suppressor cells. PMID: 23873692 Ref: Rhabdoid colorectal carcinomas: reports of two cases. PMID: 24009633 Ref: Binding of the sialic acid-binding lectin, Siglec-9, to the membrane mucin, MUC1, induces recruitment of beta-catenin and subsequent cell growth. PMID: 24045940 Ref: MUC1 activates JNK1 and inhibits apoptosis under genotoxic stress. PMID: 24055030 Ref: Mucinous differentiation in colorectal cancer: molecular, histological and clinical aspects. PMID: 24494463 |
Ref: Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. PMID: 24122770 Ref: Interference of mucin 1 inhibits progression of colon carcinoma by repression of Wnt/beta-catenin signaling. PMID: 24410135 Ref: High expression of sLex associated with poor survival in Argentinian colorectal cancer patients. PMID: 24425323 Ref: Intestinal type of lung adenocarcinoma in younger adults. PMID: 24782938 Ref: Clinicopathological utility of sialoglycoconjugates in diagnosing and treating colorectal cancer. PMID: 24876734 Ref: MUC1 aptamer conjugated to chitosan nanoparticles, an efficient targeted carrier designed for anticancer SN38 delivery. PMID: 24905777 Ref: A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer. PMID: 24943235 Ref: Micropapillary pattern and poorly differentiated clusters represent the same biological phenomenon in colorectal cancer: a proposal for a change in terminology. PMID: 25125629 Ref: Reversed polarity of the glandular epithelial cells in micropapillary carcinoma of the large intestine and the EMA/MUC1 immunostain. PMID: 25158820 Ref: REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PMID: 25295732 Ref: A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor. PMID: 25551773 |
Ref: Assessment of colloid response by nonlinear optical microscopy after preoperative radiochemotherapy for rectal carcinoma. PMID: 25436512 Ref: MUC1-C activates the TAK1 inflammatory pathway in colon cancer. PMID: 25659581 Ref: Complex of MUC1, CIN85 and Cbl in Colon Cancer Progression and Metastasis. PMID: 25675408 Ref: 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. PMID: 25713055 Ref: Immunohistochemical study of MUC1, MUC2 and MUC5AC in colorectal carcinoma and review of literature. PMID: 25731647 Ref: Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer. PMID: 25826503 Ref: Induction of duodenal mucosal tumors of intestinal epithelial cell origin showing frequent nuclear beta-catenin accumulation similar to the concurrently induced colorectal tumors in rats after treatment with azoxymethane. PMID: 25899166 Ref: Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions. PMID: 25964555 Ref: Nuclear localization of MUC1 extracellular domain in breast, head and neck, and colon cancer. PMID: 25982681 Ref: Overexpression of Vascular Endothelial Growth Factor A in Invasive Micropapillary Colorectal Carcinoma. PMID: 26068766 Ref: Loss-of-function variants in ATM confer risk of gastric cancer. PMID: 26098866 Ref: The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer. PMID: 26251612 Ref: Common Genetic Variants of PSCA, MUC1 and PLCE1 Genes are not Associated with Colorectal Cancer. PMID: 26320491 Ref: Isolation and characterization of circulating micro(nano)vesicles in the plasma of colorectal cancer patients and their interactions with tumor cells. PMID: 26324403 Ref: MUC1 Predicts Colorectal Cancer Metastasis: A Systematic Review and Meta-Analysis of Case Controlled Studies. PMID: 26367866 Ref: Prognostic Significance of Mucin Antigen MUC1 in Various Human Epithelial Cancers: A Meta-Analysis. PMID: 26683959 |
Ref: Acquired resistance to HSP90 inhibitor 17-AAG and increased metastatic potential are associated with MUC1 expression in colon carcinoma cells. PMID: 26872308 Ref: Dietary flaxseed modulates the colonic microenvironment in healthy C57Bl/6 male mice which may alter susceptibility to gut-associated diseases. PMID: 26878783 Ref: Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer. PMID: 26898938 Ref: Double targeting and aptamer-assisted controlled release delivery of epirubicin to cancer cells by aptamers-based dendrimer in vitro and in vivo. PMID: 26987703 Ref: Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon cancer. PMID: 27015647 Ref: Adhesion molecules in peritoneal dissemination: function, prognostic relevance and therapeutic options. PMID: 27074785 Ref: Can supplementation of phytoestrogens/insoluble fibers help the management of duodenal polyps in familial adenomatous polyposis? PMID: 27207660 Ref: MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance. PMID: 27298226 Ref: Differential expression of mucins in Middle Eastern patients with colorectal cancer. PMID: 27347157 Ref: Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential. PMID: 27545199 Ref: DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up. PMID: 27709558 |
Ref: Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance. PMID: 27705923 Ref: Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer. PMID: 28153010 Ref: Chitosan-modified PLGA nanoparticles tagged with 5TR1 aptamer for in vivo tumor-targeted drug delivery. PMID: 28412238 Ref: SN38 conjugated hyaluronic acid gold nanoparticles as a novel system against metastatic colon cancer cells. PMID: 28455135 Ref: Histochemical and immunohistochemical study of mucinous rectal carcinoma. PMID: 28616090 Ref: The aspirin metabolite salicylate inhibits lysine acetyltransferases and MUC1 induced epithelial to mesenchymal transition. PMID: 28717171 Ref: MUC1 O-glycosylation contributes to anoikis resistance in epithelial cancer cells. PMID: 28725490 Ref: Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells. PMID: 28731466 Ref: Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity. PMID: 28745318 Ref: Characterisation of tumour-derived microvesicles in cancer patients' blood and correlation with clinical outcome. PMID: 28804596 Ref: Poorly Differentiated Clusters in Colorectal Adenocarcinomas Share Biological Similarities with Micropapillary Patterns as well as Tumor Buds. PMID: 28875602 Ref: Genomic alterations in mucins across cancers. PMID: 28978023 |
Ref: Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies with MVA-betaGal and MVA-MUC1 (TG4010) in a murine tumor model. PMID: 28925793 Ref: MUC1- and Survivin-based DNA Vaccine Combining Immunoadjuvants CpG and interleukin-2 in a Bicistronic Expression Plasmid Generates Specific Immune Responses and Antitumour Effects in a Murine Colorectal Carcinoma Model. PMID: 29193199 Ref: Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases. PMID: 29438965 Ref: Clinical value of a diagnostic score for colon cancer based on serum CEA, CA19-9, cytokeratin-1 and mucin-1. PMID: 29734875 Ref: Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis. PMID: 29782466 Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: Soluble PD-1-based vaccine targeting MUC1 VNTR and survivin improves anti-tumor effect. PMID: 29894719 Ref: Chemoradiotherapy-induced Changes in Mucinous Components in Rectal Cancer Tissue: Evaluation on High Iron Diamine-alcian Blue and Mucin 1 Staining. PMID: 30061249 Ref: Enhancement of anti-tumor effect of plasmid DNA-carrying MUC1 by the adjuvanticity of FLT3L in mouse model. PMID: 30111221 Ref: Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids. PMID: 30111774 Ref: Role of transmembrane glycoprotein mucin 1 (MUC1) in various types of colorectal cancer and therapies: Current research status and updates. PMID: 30257347 Ref: Modified apple polysaccharide influences MUC-1 expression to prevent ICR mice from colitis-associated carcinogenesis. PMID: 30266641 Ref: MUC1 expression in colorectal carcinoma: Clinicopathological correlation and prognostic significance. PMID: 30269770 Ref: Differential expression of mucin 1 and mucin 2 in colorectal cancer. PMID: 30271081 |