Primary Site >> Colorectal Cancer
Gene >> MT-CO2
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Ref: The molecular biology of colorectal cancer development and the associated genetic events. PMID: 10645173 Ref: COX-2 inhibitors--IBC conference. 12-13 April 1999, Coronado, CA, USA. PMID: 16127636 |
Ref: Aberrant methylation of the Cyclooxygenase 2 CpG island in colorectal tumors. PMID: 10945606 |
Ref: Colon cancer chemoprevention with ginseng and other botanicals. PMID: 11748382 |
Ref: [Recent notions on intestinal cancerogenesis, their implications in genetic risk screening and preventive action of non-steroid anti-inflammatory agents]. PMID: 12145848 |
Ref: [Relationship between carcinoembryonic antigen and cyclooxygenase 2 expression and colorectal cancer]. PMID: 12600292 |
Ref: HER2 and COX2 expression in human prostate cancer. PMID: 14687789 Ref: Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. PMID: 15123663 Ref: Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer. PMID: 15173859 Ref: [Cyclooxygenase 2 inhibitors and adenomatous polyposis coli]. PMID: 15239335 Ref: Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk. PMID: 15308583 Ref: Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profiles. PMID: 15326482 Ref: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. PMID: 15526363 Ref: Is there any role for prevention strategies for colorectal cancer other than population-based screening? PMID: 15535113 Ref: Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation. PMID: 15542810 Ref: Role of new agents in the treatment of colorectal cancer. PMID: 15572089 Ref: [Cyclooxygenase 2 inhibitors and adenomatous polyposis coli]. PMID: 15899631 |
Ref: Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trial. PMID: 15894675 Ref: Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival. PMID: 16000571 |
Ref: Cyclooxygenase 2 expression in colorectal cancer with DNA mismatch repair deficiency. PMID: 16551850 Ref: New insights into the molecular pathogenesis of colorectal cancer. PMID: 20151020 |
Ref: Exploring the potential chemopreventative effect of aspirin and rofecoxib on hereditary nonpolyposis colorectal cancer-like endometrial cancer cells in vitro through mechanisms involving apoptosis, the cell cycle, and mismatch repair gene expression. PMID: 17316360 |
Ref: CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria. PMID: 18437011 Ref: The database dbEST correctly predicts gene expression in colon cancer patients. PMID: 19075689 |
Ref: Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin. PMID: 19219602 Ref: Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker. PMID: 19423505 Ref: Effect of COX2 -765G>C and c.3618A>G polymorphisms on the risk and survival of sporadic colorectal cancer. PMID: 19468846 Ref: Multiplexed cell signaling analysis of metastatic and nonmetastatic colorectal cancer reveals COX2-EGFR signaling activation as a potential prognostic pathway biomarker. PMID: 19739273 Ref: Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer. PMID: 19747744 Ref: NF-kappaB signaling pathway, inflammation and colorectal cancer. PMID: 19887045 |
Ref: Chemopreventive effect of fermented brown rice and rice bran (FBRA) on the inflammation-related colorectal carcinogenesis in ApcMin/+ mice. PMID: 19956864 Ref: Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas. PMID: 20077021 Ref: Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor. PMID: 20087348 Ref: Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. PMID: 20176655 Ref: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. PMID: 20509140 Ref: The prognostic value of c-Kit, K-ras codon 12, and p53 codon 72 mutations in Egyptian patients with stage II colorectal cancer. PMID: 20652953 Ref: Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. PMID: 20924967 |
Ref: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity. PMID: 21586136 Ref: An IkappaBalpha phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-kappaB-independent mechanism. PMID: 21620964 |
Ref: PTGS2 (COX2) -765G>C gene polymorphism and risk of sporadic colorectal cancer in Iranian population. PMID: 22173719 Ref: The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the beta-catenin signaling pathway. PMID: 22198215 Ref: Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. PMID: 22307264 Ref: Quantitative analysis of cancer-associated gene methylation connected to risk factors in Korean colorectal cancer patients. PMID: 22880157 |
Ref: Genetics, inheritance and strategies for prevention in populations at high risk of colorectal cancer (CRC). PMID: 22893205 Ref: High cyclooxygenase-2 expression is associated with advanced stages in colorectal cancer. PMID: 23898071 Ref: Anti-inflammatory effects of kudingcha methanol extract (Ilex kudingcha C.J. Tseng) in dextran sulfate sodium-induced ulcerative colitis. PMID: 23969782 Ref: Expression of NF-kB and COX2 in colorectal cancer among native Indonesians: the role of inflammation in colorectal carcinogenesis. PMID: 24045388 |
Ref: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. PMID: 24232001 Ref: Letter to editor in lieu of article published in Mol Biol Rep. 2012 May; 39(5):5219-24. PTGS2 (COX2) -765G>C gene polymorphism and risk of sporadic colorectal cancer in Iranian population. PMID: 24458827 Ref: CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC(Min)/CD24 double knockout transgenic mice. PMID: 24500912 Ref: The prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/ COX2) rs5277 polymorphism does not influence risk of colorectal cancer in an Iranian population. PMID: 24870748 Ref: Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population. PMID: 24998576 Ref: The combination of nuclear factor kappa B, cyclo-oxygenase-2 and vascular endothelial growth factor expression predicts poor prognosis in stage II and III colorectal cancer. PMID: 25368245 Ref: [The differences between three distinct locations of colorectal cancers based on clinicopathological characteristics and molecular features]. PMID: 25619220 |
Ref: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. PMID: 24497447 Ref: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. PMID: 25589620 Ref: Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse. PMID: 25794828 Ref: Cyclooxygenase-2 (COX2) gene polymorphisms and the risk of sporadic colorectal cancer and polyps among Jordanian population. PMID: 25835114 Ref: Microarray analysis of anti-cancer effects of docosahexaenoic acid on human colon cancer model in nude mice. PMID: 26131080 Ref: Mitochondrial variants in MT-CO2 and D-loop instability are involved in MUTYH-associated polyposis. PMID: 26138249 Ref: Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3beta-mediated signal transduction in colon cancer cells. PMID: 26352871 Ref: [Fecal Biomarker for Colorectal Cancer Diagnosis]. PMID: 26524859 Ref: Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth. PMID: 26586936 |
Ref: Paradoxical E-cadherin increase in 5FU-resistant colon cancer is unaffected during mesenchymal-epithelial reversion induced by gamma-secretase inhibition. PMID: 26746659 Ref: Bardoxolone Methyl Prevents High-Fat Diet-Induced Colon Inflammation in Mice. PMID: 26920068 Ref: Stress impairs the efficacy of immune stimulation by CpG-C: Potential neuroendocrine mediating mechanisms and significance to tumor metastasis and the perioperative period. PMID: 26944000 Ref: Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro-in-vivo evaluation. PMID: 27086898 Ref: A Biomarker Panel to Detect Synchronous Neoplasm in Non-neoplastic Surveillance Biopsies from Patients with Ulcerative Colitis. PMID: 27135485 Ref: IL-13 induces the expression of 11betaHSD2 in IL-13Ralpha2 dependent manner and promotes the malignancy of colorectal cancer. PMID: 27158392 Ref: Reducing liver metastases of colon cancer in the context of extensive and minor surgeries through beta-adrenoceptors blockade and COX2 inhibition. PMID: 27235931 Ref: Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model. PMID: 27612418 |
Ref: Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma. PMID: 27888614 Ref: Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis. PMID: 27897268 Ref: Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo. PMID: 28138708 Ref: Immunohistochemical Markers as Predictors of Histopathologic Response and Prognosis in Rectal Cancer Treated with Preoperative Adjuvant Therapy: State of the Art. PMID: 28326100 Ref: Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. PMID: 28385737 Ref: Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells. PMID: 28587064 Ref: MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis. PMID: 28686677 Ref: Bromoethylindole (BEI-9) redirects NF-kappaB signaling induced by camptothecin and TNFalpha to promote cell death in colon cancer cells. PMID: 29116428 Ref: POLYMORPHISM OF THE COX-2 GENE AND SUSCEPTIBILITY TO COLON AND RECTAL CANCER. PMID: 29257846 |
Ref: Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans? PMID: 29316620 Ref: The impact of polyunsaturated fatty acids on DNA methylation and expression of DNMTs in human colorectal cancer cells. PMID: 29477476 Ref: MicroRNA125 inhibits RKO colorectal cancer cell growth by targeting VEGF. PMID: 29693153 Ref: Bidirectional Regulation of COX-2 Expression Between Cancer Cells and Macrophages. PMID: 29715103 Ref: Epigallocatechin-3-Gallate Regulates Anti-Inflammatory Action Through 67-kDa Laminin Receptor-Mediated Tollip Signaling Induction in Lipopolysaccharide-Stimulated Human Intestinal Epithelial Cells. PMID: 29723847 Ref: [Advances in the research of the relationship between miRNA-29c and cancer]. PMID: 29798515 Ref: Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer. PMID: 29853736 Ref: Correlated non-nuclear COX2 and low HER2 expression confers a good prognosis in colorectal cancer. PMID: 29873317 Ref: Cytotoxic effect of 2, 5-dimethyl-celecoxib as a structural analog of celecoxib on human colorectal cancer (HT-29) cell line. PMID: 29974839 Ref: Matricellular protein periostin promotes colitis-associated colon tumorigenesis in mice. PMID: 30204842 |