Primary Site >> Colorectal Cancer
Gene >> MST1R
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Ref: Presence of RON receptor tyrosine kinase and its splicing variant in malignant and non-malignant human colonic mucosa. PMID: 10493952 Ref: Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. PMID: 10521789 |
Ref: Identification of a novel splicing product of the RON receptor tyrosine kinase in human colorectal carcinoma cells. PMID: 10910951 Ref: Overexpression and activation of the RON receptor tyrosine kinase in a panel of human colorectal carcinoma cell lines. PMID: 11082293 |
Ref: Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. PMID: 16364913 |
Ref: Blocking tumorigenic activities of colorectal cancer cells by a splicing RON receptor variant defective in the tyrosine kinase domain. PMID: 17611409 |
Ref: Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets. PMID: 18940803 |
Ref: The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice. PMID: 19452510 |
Ref: Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells. PMID: 20596675 |
Ref: Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase. PMID: 20658288 Ref: The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells. PMID: 21749705 |
Ref: Evaluation of a multi-kinase inhibitor KRC-108 as an anti-tumor agent in vitro and in vivo. PMID: 21080208 Ref: A novel variant of the RON receptor tyrosine kinase derived from colorectal carcinoma cells which lacks tyrosine phosphorylation but induces cell migration. PMID: 22975341 Ref: Identification of novel splicing variants from RON proto-oncogene pre-mRNA. PMID: 22993024 |
Ref: Efficacy of anti-RON antibody Zt/g4-drug maytansinoid conjugation (Anti-RON ADC) as a novel therapeutics for targeted colorectal cancer therapy. PMID: 25294907 |
Ref: Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer. PMID: 28320945 Ref: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer. PMID: 28672935 |