Primary Site >> Liver Cancer

Gene >> MST1

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Ref: Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.
PMID: 18697198
Ref: Mst out and HCC in.
PMID: 19878866
Ref: Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.
PMID: 19878874
Ref: Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver.
PMID: 20080689
Ref: Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development.
PMID: 21102585
Ref: Full-length Mst1 exhibits growth promoting function in human hepatocellular carcinoma cells.
PMID: 23347832
Ref: Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.
PMID: 23419361
Ref: Effect of Mst1 overexpression on the growth of human hepatocellular carcinoma HepG2 cells and the sensitivity to cisplatin in vitro.
PMID: 23419720
Ref: Yes-associated protein expression is a predictive marker for recurrence of hepatocellular carcinoma after liver transplantation.
PMID: 25632982
Ref: Markers of Hippo-Pathway Activity in Tumor Forming Liver Lesions.
PMID: 27276915
Ref: Interacting network of Hippo, Wnt/beta-catenin and Notch signaling represses liver tumor formation.
PMID: 27881216
Ref: Morin impedes Yap nuclear translocation and fosters apoptosis through suppression of Wnt/beta-catenin and NF-kappaB signaling in Mst1 overexpressed HepG2 cells.
PMID: 28366538
Ref: KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling.
PMID: 28465479
Ref: MiR-3910 Promotes the Growth and Migration of Cancer Cells in the Progression of Hepatocellular Carcinoma.
PMID: 28823082
Ref: [Research advances in the role of the Hippo signaling pathway in pathogenesis of liver cancer].
PMID: 29108216
Ref: Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma.
PMID: 28866620
Ref: Pd nanosheets with their surface coordinated by radioactive iodide as a high-performance theranostic nanoagent for orthotopic hepatocellular carcinoma imaging and cancer therapy.
PMID: 29780557
Ref: Matrine has pro-apoptotic effects on liver cancer by triggering mitochondrial fission and activating Mst1-JNK signalling pathways.
PMID: 30155612
Ref: Decursin inhibits the growth of HepG2 hepatocellular carcinoma cells via Hippo/YAP signaling pathway.
PMID: 30251417
Ref: Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation.
PMID: 30315205