Primary Site >> Stomach Cancer
Gene >> MSH6
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Ref: Lynch Syndrome PMID: 20301390 |
Ref: Evidence of genetic progression in human gastric carcinomas with microsatellite instability. PMID: 9349506 |
Ref: RER phenotype and its associated mutations in familial gastric cancer. PMID: 9498272 Ref: Mutations at coding mononucleotide repeats in gastric cancer with the microsatellite mutator phenotype. PMID: 9652743 Ref: Mutations of the human MUT S homologue 6 gene in ampullary carcinoma and gastric cancer. PMID: 9808525 Ref: Infrequent frameshift mutations of polynucleotide repeats in multiple primary cancers affecting the esophagus and other organs. PMID: 9824204 Ref: Mutational analyses of multiple target genes in histologically heterogeneous gastric cancer with microsatellite instability. PMID: 10081489 |
Ref: Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features. PMID: 10348818 Ref: Gene-environment interaction in hereditary nonpolyposis colorectal cancer with implications for diagnosis and genetic testing. PMID: 10404064 Ref: Accumulated frameshift mutations at coding nucleotide repeats during the progression of gastric carcinoma with microsatellite instability. PMID: 10496529 |
Ref: The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. PMID: 10601558 Ref: Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium. PMID: 10717241 Ref: Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes. PMID: 10719371 Ref: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation. PMID: 10918391 Ref: Microsatellite instability and alteration of E2F-4 gene in adenosquamous and squamous cell carcinomas of the stomach. PMID: 11012981 |
Ref: Germline and somatic mutations in hMSH6 and hMSH3 in gastrointestinal cancers of the microsatellite mutator phenotype. PMID: 11470537 Ref: Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. PMID: 11691784 Ref: Telomere erosion is independent of microsatellite instability but related to loss of heterozygosity in gastric cancer. PMID: 11819821 Ref: Mutations of the 'minor' mismatch repair gene MSH6 in typical and atypical hereditary nonpolyposis colorectal cancer. PMID: 14574004 |
Ref: Molecular biology of gastric cancer. PMID: 11979414 Ref: Helicobacter pylori impairs DNA mismatch repair in gastric epithelial cells. PMID: 12145807 |
Ref: Lymphocyte-rich gastric cancer: associations with Epstein-Barr virus, microsatellite instability, histology, and survival. PMID: 12861059 Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. PMID: 14518068 |
Ref: Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation. PMID: 14762794 Ref: Alterations of DNA mismatch repair proteins and microsatellite instability levels in gastric cancer cell lines. PMID: 15133479 Ref: Clinical features and mismatch repair gene mutation screening in Chinese patients with hereditary nonpolyposis colorectal carcinoma. PMID: 15309712 Ref: Characterization of mutator phenotype in familial colorectal cancer patients not fulfilling amsterdam criteria. PMID: 15448003 |
Ref: Allelic loss of 14q32 in the pathogenesis of gastrointestinal and ampullary malignancies: mapping of the target region to a 17 cM interval. PMID: 15503134 Ref: Frequent microsatellite instability in primary esophageal carcinoma associated with extraesophageal primary carcinoma. PMID: 15540218 Ref: Microsatellite instability and DNA mismatch repair deficiency testing in hereditary and sporadic gastrointestinal cancers. PMID: 15749237 Ref: HNPCC-associated small bowel cancer: clinical and molecular characteristics. PMID: 15765394 |
Ref: Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer. PMID: 17054581 |
Ref: A novel MSH2 germline mutation in a Druze HNPCC family. PMID: 17661183 Ref: Somatic mutations in mismatch repair genes in sporadic gastric carcinomas are not a cause but a consequence of the mutator phenotype. PMID: 18206535 Ref: Gastric cancer with high-level microsatellite instability: target gene mutations, clinicopathologic features, and long-term survival. PMID: 18440592 Ref: DNA mismatch repair gene methylation in gastric cancer in individuals from northern Brazil. PMID: 19181186 |
Ref: Risk and epidemiological time trends of gastric cancer in Lynch syndrome carriers in the Netherlands. PMID: 19900449 |
Ref: Non-truncating hMLH1 variants identified in Slovenian gastric cancer patients are not associated with Lynch Syndrome: a functional analysis report. PMID: 21136174 Ref: Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis. PMID: 21687951 |
Ref: The founder Ashkenazi Jewish mutations in the MSH2 and MSH6 genes in Israeli patients with gastric and pancreatic cancer. PMID: 22219001 Ref: Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. PMID: 22331944 |
Ref: Synchronous rectal and gastric cancer in a fighter pilot: aeromedical concerns. PMID: 24426647 Ref: BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer. PMID: 24759670 Ref: Gastric cancers with microsatellite instability sharing clinical features, chemoresistance and germline MSH6 variants. PMID: 26181448 |
Ref: ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas. PMID: 23887303 Ref: Pyloric gland adenoma in Lynch syndrome. PMID: 24518125 Ref: Role of endometrial cancer abnormal MMR protein in screening Lynch-syndrome families. PMID: 25400828 Ref: Epigenetic alterations in a gastric leiomyoma. PMID: 25544907 |
Ref: Microsatellite instability: an update. PMID: 25701956 Ref: [Gender-specific aspects of Lynch syndrome--an update]. PMID: 26284327 Ref: Patterns and functional implications of rare germline variants across 12 cancer types. PMID: 26689913 Ref: [A Family Affected by Lynch Syndrome Caused by MSH6 Germline Mutation]. PMID: 26805314 |
Ref: Epstein-Barr virus positivity, not mismatch repair-deficiency, is a favorable risk factor for lymph node metastasis in submucosa-invasive early gastric cancer. PMID: 26573601 Ref: A Detailed Immunohistochemical Analysis of a Large Series of Cervical and Vaginal Gastric-type Adenocarcinomas. PMID: 26685087 Ref: Comprehensive expression profiles of gastric cancer molecular subtypes by immunohistochemistry: implications for individualized therapy. PMID: 27331626 Ref: Expression of Mismatch Repair Proteins in Early and Advanced Gastric Cancer in Poland. PMID: 27527654 Ref: Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm. PMID: 27765925 |
Ref: Clinicopathologic Characteristics of Microsatellite Instable Gastric Carcinomas Revisited: Urgent Need for Standardization. PMID: 26371427 Ref: Distinct expression profile of key molecules in crawling-type early gastric carcinoma. PMID: 27734272 Ref: Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer. PMID: 28418920 Ref: Chromosomal Instability in Gastric Cancer Biology. PMID: 28431273 Ref: ALK-positive gastric inflammatory myofibroblastic tumor in an adult with familial adenomatous polyposis and diffuse fundic polyposis. PMID: 28923119 Ref: Prevalence and characteristics of hereditary non-polyposis colorectal cancer (HNPCC) syndrome in immigrant Asian colorectal cancer patients. PMID: 29237405 |
Ref: Morphologic and Immunohistochemical Appraisal of Primary Gastric Carcinomas. PMID: 29438113 Ref: Four distinct immune microenvironment subtypes in gastric adenocarcinoma with special reference to microsatellite instability. PMID: 29636988 Ref: Tumor development in Japanese patients with Lynch syndrome. PMID: 29672549 Ref: Lynch syndrome-associated endometrial carcinoma with MLH1 germline mutation and MLH1 promoter hypermethylation: a case report and literature review. PMID: 29783979 Ref: A retrospective study of extracolonic, non-endometrial cancer in Swedish Lynch syndrome families. PMID: 30386444 Ref: Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation. PMID: 30387329 |