Primary Site >> Liver Cancer

Gene >> MSH2

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Ref: Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis.
PMID: 9657101
Ref: Point mutations of ornithine decarboxylase gene are an infrequent event in colorectal cancer but a missense mutation was found in a replication error positive patient with hMSH2 germline mutation.
PMID: 9730154
Ref: Close correlation between a p53 or hMSH2 gene mutation in the tumor and survival of hepatocellular carcinoma patients.
PMID: 10024676
Ref: Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis.
PMID: 10856833
Ref: Reduced expression of hMLH1 and hMSH2 gene products in high-grade hepatocellular carcinoma.
PMID: 11332201
Ref: Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions.
PMID: 11376686
Ref: hMLH1 and hMSH2 expression in human hepatocellular carcinoma.
PMID: 11494037
Ref: Microsatellite instability in thorotrast-induced human intrahepatic cholangiocarcinoma.
PMID: 12402306
Ref: [Gene expression profile of human hepatocellular carcinoma cell lines with different metastatic potentials].
PMID: 12667318
Ref: Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray.
PMID: 12618900
Ref: Infrequent microsatellite instability in liver fluke infection-associated intrahepatic cholangiocarcinomas from Thailand.
PMID: 14506736
Ref: Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers.
PMID: 14656944
Ref: [Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma].
PMID: 15498213
Ref: Alterations of p53, Bcl-2, and hMSH2 protein expression in the cirrhotic, macroregenerative, dysplastic nodules and hepatocellular carcinomas in Upper Egypt.
PMID: 15566504
Ref: Clinicopathological and molecular genetic analysis of HNPCC in China.
PMID: 15786548
Ref: Mismatch repair genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in the pathogenesis of hepatocellular carcinoma.
PMID: 15918183
Ref: Involvement of c-myc-regulated genes in hepatocellular carcinoma related to genotype-C hepatitis B virus.
PMID: 16703398
Ref: Prognosis in patients with hepatocellular carcinoma correlates to mutations of p53 and/or hMSH2 genes.
PMID: 17350822
Ref: Sporadic childhood hepatoblastomas show activation of beta-catenin, mismatch repair defects and p53 mutations.
PMID: 17962810
Ref: Microsatellite instability in hepatocellular carcinoma in non-cirrhotic liver in patients older than 60 years.
PMID: 19054153
Ref: Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.
PMID: 19637320
Ref: Immunohistochemical expression of mismatch repair genes (hMSH2 and hMLH1) in hepatocellular carcinoma in Egypt.
PMID: 21091774
Ref: Unique genetic profile of sporadic colorectal cancer liver metastasis versus primary tumors as defined by high-density single-nucleotide polymorphism arrays.
PMID: 22222638
Ref: Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicates SEC63 as potential target gene in hepatocarcinogenesis.
PMID: 23537056
Ref: Methylation profile analysis of DNA repair genes in hepatocellular carcinoma with MS-MLPA.
PMID: 24193005
Ref: Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs.
PMID: 24400091
Ref: [Relationship between hepatocellular carcinoma and the interaction between hMSH2 polymorphisms and environmental factors].
PMID: 25369252
Ref: LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2.
PMID: 26172293
Ref: Expression of the apoptosis repressor with caspase recruitment domain (ARC) in liver metastasis of colorectal cancer and its correlation with DNA mismatch repair proteins and p53.
PMID: 26721253
Ref: MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.
PMID: 27261510
Ref: Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer.
PMID: 28949378
Ref: Rs2303428 of MSH2 Is Associated with Hepatocellular Carcinoma Prognosis in a Chinese Population.
PMID: 29874113
Ref: Decreased expression of chromodomain helicase DNA-binding protein 9 is a novel independent prognostic biomarker for colorectal cancer.
PMID: 30043858