Primary Site >> Biliary tract Cancer

Gene >> MSH2

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Ref: Analysis of microsatellite instability, TGF-beta type II receptor gene mutations and hMSH2 and hMLH1 allele losses in pancreaticobiliary maljunction-associated biliary tract tumors.
PMID: 10470113
Ref: Infrequent microsatellite instability in biliary tract cancer.
PMID: 11223838
Ref: Deficient expression of O(6)-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma.
PMID: 11986189
Ref: Establishment and characterisation of six human biliary tract cancer cell lines.
PMID: 12107841
Ref: Microsatellite alterations in liver fluke related cholangiocarcinoma are associated with poor prognosis.
PMID: 12175538
Ref: Microsatellite instability in thorotrast-induced human intrahepatic cholangiocarcinoma.
PMID: 12402306
Ref: Microsatellite instability in chronic cholecystitis is indicative of an early stage in gallbladder carcinogenesis.
PMID: 14502806
Ref: Infrequent microsatellite instability in liver fluke infection-associated intrahepatic cholangiocarcinomas from Thailand.
PMID: 14506736
Ref: Lack of microsatellite instability in neoplasms of ampulla of Vater.
PMID: 14516316
Ref: Allelic loss of 14q32 in the pathogenesis of gastrointestinal and ampullary malignancies: mapping of the target region to a 17 cM interval.
PMID: 15503134
Ref: An immunohistochemical study of the expression of cell-cycle-regulated proteins p53, cyclin D1, RB, p27, Ki67 and MSH2 in gallbladder carcinoma and its precursor lesions.
PMID: 15578423
Ref: Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder.
PMID: 15692793
Ref: Immunohistochemical expression of mismatch repair genes: a screening tool for predicting mutator phenotype in liver fluke infection-associated intrahepatic cholangiocarcinoma.
PMID: 16773692
Ref: A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.
PMID: 17051350
Ref: Prognostic factors for ampullary adenocarcinomas: tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability.
PMID: 17653761
Ref: Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time?
PMID: 17962726
Ref: Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions.
PMID: 19252434
Ref: Polymorphisms in ERCC2, MSH2, and OGG1 DNA repair genes and gallbladder cancer risk in a population of Northern India.
PMID: 20564624
Ref: Gallbladder cancer predisposition: a multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes.
PMID: 21283657
Ref: Mutations in the RAS/RAF/MAP kinase pathway commonly occur in gallbladder adenomas but are uncommon in gallbladder adenocarcinomas.
PMID: 21307665
Ref: Mucinous carcinomas of the gallbladder: clinicopathologic analysis of 15 cases identified in 606 carcinomas.
PMID: 23106580
Ref: Microsatellite instability in gallbladder carcinoma.
PMID: 25680569
Ref: Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Biliary Tract Cancers Associated with Lynch Syndrome.
PMID: 29238914
Ref: Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.
PMID: 29360550
Ref: Microsatellite Instability Occurs Rarely in Patients with Cholangiocarcinoma: A Retrospective Study from a German Tertiary Care Hospital.
PMID: 29747443