Primary Site >> Pancreatic Cancer
Gene >> MMP9
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Ref: Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. PMID: 7635566 |
Ref: Cholecystokinin receptor antagonist, loxiglumide, inhibits invasiveness of human pancreatic cancer cell lines. PMID: 8925905 Ref: Dexamethasone inhibits invasiveness of a human pancreatic cancer cell line. PMID: 21544363 |
Ref: Detection of matrix metalloproteinase activity in human pancreatic cancer. PMID: 9086544 |
Ref: Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma. PMID: 9477095 |
Ref: Matrix metalloproteinase (MMP) inhibition selectively decreases type II MMP activity in a murine model of pancreatic cancer. PMID: 9889060 Ref: Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma. PMID: 9918199 Ref: Cholecystokinin regulates the invasiveness of human pancreatic cancer cell lines via protein kinase C pathway. PMID: 10339669 Ref: Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine. PMID: 10383907 Ref: Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. PMID: 10547197 Ref: In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. PMID: 10935470 |
Ref: Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer. PMID: 10694645 Ref: Effect of matrix metalloproteinase inhibition on pancreatic cancer invasion and metastasis: an additive strategy for cancer control. PMID: 10767785 Ref: Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer. PMID: 10866312 Ref: Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis. PMID: 10914717 Ref: Matrix metalloproteinase inhibition improves survival in an orthotopic model of human pancreatic cancer. PMID: 11307097 Ref: Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs. PMID: 11448066 Ref: High collagenolytic activity in spontaneously highly metastatic variants derived from a human pancreatic cancer cell line (SUIT-2) in nude mice. PMID: 11688961 Ref: In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs. PMID: 11729853 |
Ref: Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression. PMID: 11181677 Ref: The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer. PMID: 11332689 Ref: The epidermal growth factor receptor as a target for cancer therapy. PMID: 11350723 Ref: Invasiveness and MMP expression in pancreatic carcinoma. PMID: 11368535 Ref: Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo. PMID: 11773977 Ref: Expression of thrombospondin-1 in human pancreatic adenocarcinomas: role in matrix metalloproteinase-9 production. PMID: 11882904 |
Ref: Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer. PMID: 11854622 Ref: Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials. PMID: 12167581 Ref: Identification of rat pancreatic carcinoma genes associated with lymphogenous metastasis. PMID: 12174879 Ref: Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. PMID: 12630765 |
Ref: RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis. PMID: 12738734 Ref: Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. PMID: 12738744 Ref: Regulation of pancreatic stellate cell function in vitro: biological and molecular effects of all-trans retinoic acid. PMID: 12906928 Ref: Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. PMID: 12947321 Ref: Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. PMID: 12947332 Ref: Evaluation of urinary plasminogen activator, its receptor, matrix metalloproteinase-9, and von Willebrand factor in pancreatic cancer. PMID: 14581368 Ref: Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis. PMID: 14598883 Ref: Detection of type IV collagenase activity in malignant ascites. PMID: 14606104 Ref: Role of matrix metalloproteinases 2 and 9 in determination of invasive potential of pancreatic tumors. PMID: 14968170 |
Ref: Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells. PMID: 15239215 Ref: Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells. PMID: 15257104 Ref: Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer. PMID: 15300189 Ref: [Inhibitory effects of high mobility group box 1 antisense nucleotide on invasion of human pancreatic cancer cell line PCNA-1]. PMID: 15363197 |
Ref: Macrophage inflammatory protein-3alpha promotes pancreatic cancer cell invasion. PMID: 15652956 Ref: [Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]. PMID: 15694029 Ref: Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia. PMID: 15867264 Ref: Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2. PMID: 15879623 Ref: Combination therapy with tumor-lysate pulsed dendritic cells and antiangiogenic drug TNP-470 for mouse pancreatic cancer. PMID: 15906361 Ref: Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line. PMID: 16258364 |
Ref: Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions. PMID: 16340751 Ref: Analysis of the invasion-metastasis mechanism in pancreatic cancer: involvement of plasmin(ogen) cascade proteins in the invasion of pancreatic cancer cells. PMID: 16391791 Ref: Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. PMID: 16510599 Ref: Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis. PMID: 16778198 Ref: Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. PMID: 16885366 Ref: Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer. PMID: 17034997 Ref: Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis. PMID: 17120744 |
Ref: Combination therapy of human pancreatic cancer implanted in nude mice by oral fluoropyrimidine anticancer agent (S-1) with interferon-alpha. PMID: 16699793 Ref: In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. PMID: 17131310 Ref: Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. PMID: 17200110 Ref: Expression of matrix metalloproteinase 9 in pancreatic ductal carcinoma is associated with tumor metastasis formation. PMID: 17378244 Ref: Down-regulation of the nuclear factor-kappaB by lidamycin in association with inducing apoptosis in human pancreatic cancer cells and inhibiting xenograft growth. PMID: 17487403 Ref: Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis. PMID: 17545513 Ref: Action of antiproteases on pancreatic cancer cells. PMID: 17625304 Ref: Association of axon guidance factor semaphorin 3A with poor outcome in pancreatic cancer. PMID: 17631638 Ref: Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. PMID: 17804744 Ref: Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice. PMID: 18030366 |
Ref: EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer. PMID: 17981559 Ref: Expression pattern and circulating levels of endostatin in patients with pancreas cancer. PMID: 18360823 Ref: The potential molecular mechanism of overexpression of uPA, IL-8, MMP-7 and MMP-9 induced by TRAIL in pancreatic cancer cell. PMID: 18397859 Ref: Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation. PMID: 18410405 Ref: Forced expression of MMP9 rescues the loss of angiogenesis and abrogates metastasis of pancreatic tumors triggered by the absence of host SPARC. PMID: 18445772 Ref: TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer. PMID: 18528859 Ref: Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients. PMID: 18706098 Ref: The novel hypoxic cell radiosensitizer, TX-1877 has antitumor activity through suppression of angiogenesis and inhibits liver metastasis on xenograft model of pancreatic cancer. PMID: 18762366 Ref: Thrombospondin-2 inhibits tumor cell invasion through the modulation of MMP-9 and uPA in pancreatic cancer cells. PMID: 21479427 |
Ref: Synergistic growth inhibitory effects of the dual endothelin-1 receptor antagonist bosentan on pancreatic stellate and cancer cells. PMID: 18612819 Ref: RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer. PMID: 18794910 Ref: Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases. PMID: 19223533 Ref: The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target. PMID: 19252414 Ref: Clinical significance of the measurements of serum matrix metalloproteinase-9 and its inhibitor (tissue inhibitor of metalloproteinase-1) in patients with pancreatic cancer: metalloproteinase-9 as an independent prognostic factor. PMID: 19629003 Ref: Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. PMID: 19670328 Ref: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. PMID: 19722233 Ref: Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol. PMID: 19724861 |
Ref: Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer. PMID: 19908231 Ref: Hypoxia activates heparanase expression in an NF-kappaB dependent manner. PMID: 19956890 Ref: ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts. PMID: 20023433 Ref: Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells. PMID: 20031158 Ref: A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes. PMID: 20067773 Ref: Comparison of circulating MMP-9, TIMP-1 and CA19-9 in the detection of pancreatic cancer. PMID: 20332475 Ref: FoxM1 is a novel target of a natural agent in pancreatic cancer. PMID: 20354770 Ref: Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway. PMID: 20367887 Ref: beta2-adrenergic antagonists suppress pancreatic cancer cell invasion by inhibiting CREB, NFkappaB and AP-1. PMID: 20424515 Ref: MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity. PMID: 20460539 Ref: CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation. PMID: 20501830 Ref: Novel blood biomarkers of pancreatic cancer-associated diabetes mellitus identified by peripheral blood-based gene expression profiles. PMID: 20571492 Ref: Lentivirus-mediated reversion-inducing cysteine-rich protein with Kazal motifs gene transfer suppresses pancreatic cancer invasion in vitro. PMID: 20635007 Ref: Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer. PMID: 20647339 Ref: Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells. PMID: 20824368 Ref: {Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. PMID: 20864511 Ref: Ukrain affects pancreas cancer cell phenotype in vitro by targeting MMP-9 and intra-/extracellular SPARC expression. PMID: 20975318 |
Ref: Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling. PMID: 21283078 Ref: Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer. PMID: 21338440 Ref: The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. PMID: 21339745 Ref: Activated KrasG(1)(2)D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin. PMID: 21364589 Ref: Neutrophil granulocyte derived MMP-9 is a VEGF independent functional component of the angiogenic switch in pancreatic ductal adenocarcinoma. PMID: 21442180 Ref: Garcinol inhibits cell proliferation and promotes apoptosis in pancreatic adenocarcinoma cells. PMID: 21462088 Ref: Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-kappaB pathway. PMID: 21479633 Ref: Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition. PMID: 21484229 Ref: Antiproliferative and antimetastatic effects of emodin on human pancreatic cancer. PMID: 21491088 Ref: Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. PMID: 21558393 Ref: The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody. PMID: 21621407 Ref: Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer. PMID: 21760774 Ref: Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases. PMID: 21989104 Ref: [Anti-metastasis effect of thymoquinone on human pancreatic cancer]. PMID: 22007514 Ref: Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets. PMID: 22066019 Ref: Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PMID: 22164219 Ref: [Inhibitory effects of thymoquinone on human pancreatic carcinoma orthotopically implanted in nude mice]. PMID: 22340651 Ref: [Experimental study on anti-metastasis effect of emodin on human pancreatic cancer]. PMID: 22375400 |
Ref: Qingyihuaji formula inhibits progress of liver metastases from advanced pancreatic cancer xenograft by targeting to decrease expression of Cyr61 and VEGF. PMID: 21382954 Ref: Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets. PMID: 21935918 Ref: Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer. PMID: 21954965 Ref: Grape-seed procyanidins inhibit the in vitro growth and invasion of pancreatic carcinoma cells. PMID: 22015975 Ref: Keratinocyte growth factor induces matrix metalloproteinase-9 expression and correlates with venous invasion in pancreatic cancer. PMID: 22159401 Ref: Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. PMID: 22234980 Ref: Secreted 70kDa lumican stimulates growth and inhibits invasion of human pancreatic cancer. PMID: 22266188 Ref: Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-kappaB signaling pathways. PMID: 22322442 Ref: Effects and mechanism of integrin-beta1 gene expression inhibited by shRNA in invasion of pancreatic carcinoma PANC-1 cells. PMID: 22353524 Ref: NOP14 promotes proliferation and metastasis of pancreatic cancer cells. PMID: 22425761 Ref: The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. PMID: 22513004 Ref: Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer. PMID: 22532830 Ref: Rap1GAP alters leukemia cell differentiation, apoptosis and invasion in vitro. PMID: 22614916 Ref: Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells. PMID: 22626610 Ref: The antitumor activity of recombinant antitumor antiviral protein and the associated molecular mechanism in pancreatic tumor cells. PMID: 22783925 Ref: MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1. PMID: 22791819 Ref: Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis. PMID: 22876305 Ref: The effects of genistein on transforming growth factor-beta1-induced invasion and metastasis in human pancreatic cancer cell line Panc-1 in vitro. PMID: 22884073 Ref: Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicine. PMID: 22949663 Ref: Exocrine pancreatic carcinogenesis and autotaxin expression. PMID: 22952646 Ref: REG4 contributes to the invasiveness of pancreatic cancer by upregulating MMP-7 and MMP-9. PMID: 22957785 Ref: Metalloproteinase 2 and 9 activity in the development of pancreatic cancer. PMID: 22985699 Ref: miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. PMID: 23070684 Ref: Retraction. Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling. PMID: 23191991 Ref: Naringenin decreases invasiveness and metastasis by inhibiting TGF-beta-induced epithelial to mesenchymal transition in pancreatic cancer cells. PMID: 23300530 Ref: Microenvironment elements involved in the development of pancreatic cancer tumor. PMID: 23304126 Ref: Concentrations and activities of metalloproteinases 2 and 9 and their inhibitors (TIMPS) in chronic pancreatitis and pancreatic adenocarcinoma. PMID: 23388475 |
Ref: Knockdown of angiopoietin-2 suppresses metastasis in human pancreatic carcinoma by reduced matrix metalloproteinase-2. PMID: 22457202 Ref: Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer. PMID: 23111540 Ref: GPC-1 may serve as a predictor of perineural invasion and a prognosticator of survival in pancreatic cancer. PMID: 23270819 Ref: Interaction of the sympathetic nerve with pancreatic cancer cells promotes perineural invasion through the activation of STAT3 signaling. PMID: 23288783 Ref: Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells. PMID: 23538603 Ref: Concentration of gelatinases and their tissue inhibitors in pancreatic inflammatory and neoplastic tumors and their influence on the early postoperative course. PMID: 23585206 Ref: Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice. PMID: 23684930 Ref: SDF-1alpha upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines. PMID: 23712777 Ref: Role of Peroxisome Proliferator-Activated Receptor beta/delta and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells. PMID: 23737761 Ref: eEF1A2 promotes cell migration, invasion and metastasis in pancreatic cancer by upregulating MMP-9 expression through Akt activation. PMID: 23739844 Ref: beta2-AR-HIF-1alpha: a novel regulatory axis for stress-induced pancreatic tumor growth and angiogenesis. PMID: 23745588 Ref: M2-polarized tumor-associated macrophages promoted epithelial-mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway. PMID: 23752129 Ref: The estimation of metaloproteinases and their inhibitors blood levels in patients with pancreatic tumors. PMID: 23768069 Ref: alpha-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells. PMID: 23833675 Ref: Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. PMID: 23920124 Ref: Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-kappaB pathway. PMID: 23992306 Ref: Indometacin ameliorates high glucose-induced proliferation and invasion via modulation of e-cadherin in pancreatic cancer cells. PMID: 23992308 Ref: A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer. PMID: 23993964 Ref: HIF1 contributes to hypoxia-induced pancreatic cancer cells invasion via promoting QSOX1 expression. PMID: 24008827 Ref: Digitoflavone inhibits IkappaBalpha kinase and enhances apoptosis induced by TNFalpha through downregulation of expression of nuclear factor kappaB-regulated gene products in human pancreatic cancer cells. PMID: 24146961 Ref: CXCL12-CXCR4 promotes proliferation and invasion of pancreatic cancer cells. PMID: 24175834 Ref: [6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- kappa B/Snail Signal Transduction Pathway. PMID: 24204396 |
Ref: RNA interference against MDM2 suppresses tumor growth and metastasis in pancreatic carcinoma SW1990HM cells. PMID: 22200978 Ref: Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides. PMID: 23624916 Ref: Decreased TIP30 expression predicts poor prognosis in pancreatic cancer patients. PMID: 24037692 Ref: alpha-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model. PMID: 24295217 Ref: Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases. PMID: 24336522 Ref: Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-kappaB signaling by 6-shogaol. PMID: 24424498 Ref: Antitumor efficacy of alpha-solanine against pancreatic cancer in vitro and in vivo. PMID: 24505326 Ref: Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression. PMID: 24526468 Ref: Pancreatic satellite cells derived galectin-1 increase the progression and less survival of pancreatic ductal adenocarcinoma. PMID: 24595374 Ref: S100P antibody-mediated therapy as a new promising strategy for the treatment of pancreatic cancer. PMID: 24637492 Ref: ZIP4, a novel determinant of tumor invasion in hepatocellular carcinoma, contributes to tumor recurrence after liver transplantation. PMID: 24643086 Ref: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. PMID: 24694877 Ref: alpha-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway. PMID: 24812621 Ref: Mmp-9 responsive PEG cleavable nanovesicles for efficient delivery of chemotherapeutics to pancreatic cancer. PMID: 24827725 Ref: Protein Kinase D family kinases: roads start to segregate. PMID: 24847910 Ref: Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VEcadherin/EphA2/MMP9/MMP2 expression. PMID: 24938458 Ref: Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells. PMID: 24949471 Ref: KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-kappaB and VEGF-C. PMID: 24982355 Ref: Clobenpropit enhances anti-tumor effect of gemcitabine in pancreatic cancer. PMID: 25024609 Ref: Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from Kras(G12D) mice. PMID: 25050737 Ref: Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. PMID: 25111230 Ref: In vitro and in vivo biological evaluation of O-carboxymethyl chitosan encapsulated metformin nanoparticles for pancreatic cancer therapy. PMID: 25115827 Ref: SUMO-specific protease 1 regulates pancreatic cancer cell proliferation and invasion by targeting MMP-9. PMID: 25217324 Ref: Reversion of trichostatin A resistance via inhibition of the Wnt signaling pathway in human pancreatic cancer cells. PMID: 25224651 Ref: Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro. PMID: 25260978 Ref: [The role of Gli1 in the invasion and migration of pancreatic cancer cells]. PMID: 25262609 Ref: Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction. PMID: 25274283 Ref: Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer models. PMID: 25482337 Ref: Huachansu injection inhibits metastasis of pancreatic cancer in mice model of human tumor xenograft. PMID: 25496480 |
Ref: GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK. PMID: 25218495 Ref: Ratiometric activatable cell-penetrating peptides label pancreatic cancer, enabling fluorescence-guided surgery, which reduces metastases and recurrence in orthotopic mouse models. PMID: 25319581 Ref: MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer. PMID: 25471789 Ref: Oil palm phenolics (OPP) inhibit pancreatic cancer cell proliferation via suppression of NF-kappaB pathway. PMID: 25550539 Ref: [CCL21 promotes the metastasis of human pancreatic cancer Panc-1 cells via epithelial- mesenchymal transition]. PMID: 25575049 Ref: miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases. PMID: 25883224 Ref: Gli1 promotes transforming growth factor-beta1- and epidermal growth factor-induced epithelial to mesenchymal transition in pancreatic cancer cells. PMID: 25979438 Ref: Gd-Metallofullerenol Nanomaterial Suppresses Pancreatic Cancer Metastasis by Inhibiting the Interaction of Histone Deacetylase 1 and Metastasis-Associated Protein 1. PMID: 26083726 Ref: Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells. PMID: 26282200 Ref: Peroxisome proliferator-activated receptor-gamma inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN. PMID: 26299428 Ref: Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination. PMID: 26325075 Ref: Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial-mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells. PMID: 26527884 Ref: The co-expression of MMP-9 and Tenascin-C is significantly associated with the progression and prognosis of pancreatic cancer. PMID: 26652622 Ref: Role of sphingosine 1-phosphate in human pancreatic cancer cells proliferation and migration. PMID: 26884951 |
Ref: Paracrine tumor signaling induces transdifferentiation of surrounding fibroblasts. PMID: 26467073 Ref: Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro. PMID: 26516023 Ref: Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer. PMID: 26649143 Ref: Piperlongumine Suppresses Growth and Sensitizes Pancreatic Tumors to Gemcitabine in a Xenograft Mouse Model by Modulating the NF-kappa B Pathway. PMID: 26667450 Ref: Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels. PMID: 26692441 Ref: Activation of Toll-like receptor 7 regulates the expression of IFN-lambda1, p53, PTEN, VEGF, TIMP-1 and MMP-9 in pancreatic cancer cells. PMID: 26718740 Ref: Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade. PMID: 27083074 Ref: HIC1 attenuates invasion and metastasis by inhibiting the IL-6/STAT3 signalling pathway in human pancreatic cancer. PMID: 27085461 Ref: Investigation of juglone effects on metastasis and angiogenesis in pancreatic cancer cells. PMID: 27155528 Ref: Ovatodiolide of Anisomeles indica Exerts the Anticancer Potential on Pancreatic Cancer Cell Lines through STAT3 and NF-kappaB Regulation. PMID: 27242913 Ref: The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer. PMID: 27287498 Ref: Celecoxib suppresses fibroblast growth factor-2 expression in pancreatic ductal adenocarcinoma PANC-1 cells. PMID: 27430377 Ref: Paeoniflorin inhibits human pancreatic cancer cell apoptosis via suppression of MMP-9 and ERK signaling. PMID: 27446455 Ref: TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo. PMID: 27459514 Ref: Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells. PMID: 27471397 Ref: Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow. PMID: 27489361 Ref: Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer. PMID: 27545397 Ref: Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-kappaB pathway. PMID: 27572503 Ref: Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway. PMID: 27698853 Ref: C60(OH)22: a potential histone deacetylase inhibitor with anti-angiogenic activity. PMID: 27714131 Ref: Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth. PMID: 27758098 |
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